15th International Conference on Genomics and Systems Biology of Human Disease and Aging

Program - Sunday, June 23

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 

    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport

    Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~65 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.

    Accommodation Tax

    An accommodation tax of € 10.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

     Accommodations

    Accommodations for the conference are at the Avra Imperial Hotel.  The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Avra Imperial Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour

    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast

    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Sunday, June 23

07:30 AM - 08:25 AM
Breakfast
08:25 AM - 08:30 AM
Welcome and Opening Remarks
Cancer
Chair: Bing Ren
08:30 AM - 08:55 AM
1
Hippo Signaling and Cancer
Kun-Liang Guan
08:55 AM - 09:20 AM
2
Spatial transcriptomic analysis of triple-negative breast cancer occurring during pregnancy and post-involution.
Dasha Veraksa1, Kavitha Mukund1, Jerneja Tomsic2, David Frankhouser2, Augusto Ochoa3, Lucio Miele3, Shankar Subramaniam1, and Victoria Seewaldt2
09:20 AM - 09:45 AM
3
A Spatial and cellular landscape of triple negative breast cancer
Shankar Subramaniam1, Kavitha Mukund1, Zahra Mesrizadeh1, Darya Veraksa1, Jerneja Tomsic2, David Frankhouser2, Augusto Ochoa3, Jovanny Zabaleta3, and Victoria Seewaldt2
09:45 AM - 10:10 AM
4
A genome-wide single-cell 3D genome atlas of lung cancer progression
Miao Liu1, Shengyan Jin1, Sherry S Agabiti1, Tyler B Jensen1, Tianqi Yang1, Jonathan SD Radda1, Christian F Ruiz1, Gabriel Baldissera1, Mandar D Muzumdar1, and Siyuan Wang1
10:10 AM - 10:35 AM
5
GATA6, a novel regulator of 3D genome organization in colorectal cancer
Feng Yue
10:35 AM - 11:00 AM
6
Novel strategies to enhance the efficacy of CAR T cell immunotherapy in brain tumors
Dinorah Friedmann-Morvinski1, Alina Brosque1, Dana Tarab4, Shani Nahmias2, Yarden Engel3, Dan Peer4, Marcelle Machluf2, Michael Berger3, and Dinorah Friedmann-Morvinski1
11:00 AM - 11:40 AM
Coffee Break and Poster Viewing
Senescence and Aging (I)
Chair: Ana Pombo
11:40 AM - 12:05 PM
7
The Epigenomic Landscape of Retrotransposon Expression in Cellular Senescence and Neurodegeneration
John M Sedivy
12:05 PM - 12:30 PM
8
Reactivation of neurogenic niches in aged mammalian brain
Bogdan Bintu
12:30 PM - 12:55 PM
9
Augmented R-loops as the Underlying Mechanism for Cockayne Syndrome-associated Neurological Disorder and Premature Aging
Xiang-Dong Fu
12:55 PM - 01:20 PM
10
Stem Cell-Mediated Mechanisms of Functional Neuromusculoskeletal Restoration in Naturally Aged Mice
Seth Thompson1, Chelsea Rugel1, Kavitha Mukund 4, Tanvi Potluri5, Rajeswari Pichika 6, Richard Lieber1, Scott Budinger3, Shankar Subramaniam4, and Mitra Lavasani1
01:20 PM - 01:45 PM
11
The Ying Yang of retrotransposons activity in the soma: from junk to RNA tools for antiaging and tissue regeneration
Valerio Orlando
01:45 PM - 02:00 PM
12
Single-Cell Analysis of Aging-Associated Gene Regulatory Programs in the Human Hippocampus
Nathan R Zemke1, Sainath Mamde1, Seoyeon Lee1, Nicole Berchtold2, Hannah Indralingam1, Weronika Bartosik1, Pik Ki Lau1, Keyi Dong1, Bing Yang1, Amanda Yang1, Yasmine Tani1, Chumo Chen1, Qiurui Zeng1, Carl W Cotman2, Xiangmin Xu3, and Bing Ren1
02:00 PM - 03:10 PM
Lunch and Informal Discussions
Epigenetics (1st session)
Chair: Hemali Phatnani
03:10 PM - 03:35 PM
13
Extensive folding variability between homologous chromosomes in mammalian cells
Ibai Irastorza-Azcarate1, Alexander Kukalev1, Rieke Kempfer1,4, Christoph Thieme1, Julia Markowski1,4, Roland Schwarz1, Stefan Kempa1, Guido Mastrobuoni1, Bing Ren3,4, and Ana Pombo1,4
03:35 PM - 04:00 PM
14
3D chromatin structure at the intersection of Toxicology and Disease
Yvonne Fondufe-Mittendorf
04:00 PM - 04:25 PM
15
Chromatin Regulation and Cancer
Yang Shi
04:25 PM - 04:50 PM
16
Genome organization in and around the nucleolus
Raffaella Santoro
04:50 PM - 05:15 PM
17
TEM-seq: ultra-sensitive multiomics link chromatin features and DNA methylation
Bryan J Venters1, Vishnu U. Sunitha Kumary1, Allison Hickman1, Anup Vaidya1, James Anderson1, Ryan J Ezell1, Jonathan M Burg1, Louise Williams2, Chaithanya Ponnaluri2, Hang Geong Chin2, Pierre Esteve2, Isaac Meek2, Zu-Wen Sun1, Martis W. Cowles1, Sriharsa Pradhan2, and Michael-Christopher Keogh1
05:15 PM - 05:30 PM
18
Global regulation of Heterochromatin Landscape and Gene expression in pediatric Leukemia
Sinisa Dovat, Yali Ding, Bing He, Daniel Bogush, and Joseph Schramm
05:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions