9th International Conference on Osteoimmunology: Interactions of the Immune and Skeletal Systems

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 

    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport

    You want to arrive at the Athens International Airport (code: ATH). You can take a taxi from the airport to the hotel. You may also rent a car at the airport and drive to the conference center. 

    Accommodation Tax

    An accommodation tax of € 10.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations

    Accommodations for the conference are at the Wyndham Loutraki Hotel.  The hotel is located in Loutraki, 114 km from the Athens International Airport

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Wyndham Loutraki Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    Ancient Corinth Tour

    Buses for the Ancient Corinth tour will depart from the hotel front lobby at 3:00 pm. Badges are required for participation. 

    Breakfast

    Breakfast for registered participants and registered accompanying persons will be served at the Wyndham Loutraki Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Monday, May 27

06:30 PM - 07:30 PM
Conference Registration
07:30 PM - 10:30 PM
Welcome Reception and Dinner

Tuesday, May 28

08:00 AM - 09:00 AM
Breakfast
Session I: Stromal osteoimmunology
Chairs: Hiroshi Takayanagi and Iannis Adamopoulos
09:00 AM - 09:30 AM
1
Vascular Regulation of Immune System Aging
Anjali Kusumbe
09:30 AM - 10:00 AM
2
Regulation of bone turnover and hematopoiesis by bone marrow adipoprogenitors
Ling Qin
10:00 AM - 10:30 AM
3
Protection, Damage and Repair in the Joint - Fibroblasts Decide!
Adam Croft
10:30 AM - 11:00 AM
4
Gas or Brake: Inflammatory bone resorption and a novel osteoclastic niche
Baohong Zhao
11:00 AM - 11:30 AM
Coffee Break and Poster Viewing
Session II :Diversity in the bone marrow and stem cells
Chairs: Hiroshi Takayanagi and Iannis Adamopoulos
11:30 AM - 12:00 PM
5
Skeletal stem cells governing site-specific pathology in the spine and beyond
Matthew B Greenblatt
12:00 PM - 12:20 PM
6
The stromal defense against cancer invasion by the periosteum
Masayuki Tsukasaki
12:20 PM - 12:40 PM
7
Clec3b+ fibroadipogenic progenitors in fracture healing and heterotopic ossification
Ugur Ayturk
12:40 PM - 01:00 PM
8
Bone marrow endosteal stem cells coordinate active osteogenesis and tumorigenesis in young bones
Yuki Matsushita
01:00 PM - 01:20 PM
9
Clearing human bone marrow reveals spatial heterogeneity of the stromal niche
tsz long Chu1, Emil Krukov1, Yu-Wei Chang3, Ostap Dregval2, Dana Trompet2, Misty Shuo Zhang1, Emiliano Gomez Ruiz3, Joana Pereira4, Björn Barenius5, Lars Sävendahl6, Giovanni Volpe3, and Andrei S Chagin2
01:20 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses depart from hotel lobby)

Wednesday, May 29

08:00 AM - 09:00 AM
Breakfast
Session III : Big data-driven deconvolution
Chairs: Natalie Sims and Georg Schett
09:00 AM - 09:30 AM
10
Identification of Age-associated T (ThA) cells that increase with aging and possess both cytotoxic activity and B cell helper function
Keishi Fujio
09:30 AM - 09:50 AM
11
type 2 inflammation and associated diseases
Yihong Wan
09:50 AM - 10:10 AM
12
Quantification of the escape from X chromosome inactivation with the million cell-scale human single-cell omics datasets reveals heterogeneity of escape across cell types and tissues
Yoshihiko Tomofuji1, Yukinori Okada1, Ryuya Edahiro2, Yuya Shirai2, Kyuto Sonehara1, Shinichi Namba1, and Tomohiro Yata2
10:10 AM - 10:30 AM
13
Characterization of the secretory lysosome reveals new regulators of osteoclast function and endolysosomal homeostasis
Nathan J. Pavlos
10:30 AM - 10:50 AM
14
Can AI be used to write credible scientific review articles?
Melissa A. Kacena1,3, Lilian I. Plotkin2,3, and Jill C. Fehrenbacher4
10:50 AM - 11:30 AM
Coffee Break and Poster Viewing
Session IV: New discoveries in disease pathogenesis
Chairs: Natalie Sims and Georg Schett
11:30 AM - 12:00 PM
15
Role of cytosolic DNA sensing pathways in autoimmunity and bone
Ellen M. Gravallese
12:00 PM - 12:20 PM
16
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
Aline Bozec1, Katerina Kachler1, Darja Andreev1, Shreeya Thapa1, Dmytro Royzman3, Andreas Gießl4, Xianyi Meng1, Alexander Steinkasserer3, and Georg Schett1
12:20 PM - 12:40 PM
17
Advances in imaging approaches to study cell biology in bone
Karl J Lewis
12:40 PM - 01:00 PM
18
Differential effects of the PTH-responsive citrate transporter SLC13A5 during growth and aging
Naomi Dirckx
01:00 PM - 02:30 PM
Lunch and Informal Discussions
02:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses depart from hotel lobby)

Thursday, May 30

08:00 AM - 09:00 AM
Breakfast
Session V: Aging and rejuvenating the osteoimmune system-1
Chairs: Lionel Ivashkiv and Deborah Veis
09:00 AM - 09:30 AM
19
Immune cell-mediated age-related osteoporosis
Brendan F. Boyce
09:30 AM - 10:00 AM
20
Preosteoclast-Secreted PDGF-BB in Skeletal Aging and Vascular Aging
Mei Wan
10:00 AM - 10:30 AM
21
Bone marrow-based inflammatory memory as a mechanistic basis for the comorbidity of arthritis and periodontitis
George Hajishengallis
10:30 AM - 11:00 AM
22
Use of medicinal secretory cells to alleviate pain and increase function in OA.
Hicham Drissi
11:00 AM - 11:30 AM
Coffee Break and Poster Viewing
Session VI: Cutting edge
Chairs: Lionel Ivashkiv and Deborah Veis
11:30 AM - 11:45 AM
23
How does OPG limit vascular calcification?
Yutaro Ando1, Masayuki Tsukasaki2, and Hiroshi Takayanagi1
11:45 AM - 12:00 PM
24
A novel macrophage subset promotes bone regeneration through the activation of Wnt signals in mesenchymal stromal cells.
Zhifeng He1, Linan Shi1, Toshihide Mizoguchi2, Ruoxuan Li1, Yuki Matsushita3, Shinichiro Ito2, Yuko Nakamichi1, Kohei Murakami4, Kazuo Okamoto5, Hiroshi Takayanagi6, Nobuyuki Udagawa7, and Yasuhiro Kobayashi1
12:00 PM - 12:15 PM
25
The osteoimmunology of bone metastasis: the roles of osteoblasts in regulation of anti-tumoral immunity
Eun Jung Lee and Serk In Park
12:15 PM - 12:30 PM
26
Novel Role of Megakaryocytes in Bone’s Anabolic Response to Loading
Amy Creecy1, Sonali Karnik1, Ola Awosanya1, Tyler Hesselbrock1, Pratibha Singh2, Angela Bruzzaniti3, and Melissa Kacena1
12:30 PM - 12:45 PM
27
Emerging roles of the long pentraxin PTX3 in Staphylococcus aureus-dependent osteomyelitis
Valentina Possetti1,4, Raffaella Parente2, Dario Strina3, Valentina Granata4, Maria Lucia Schiavone5, Francesca R Liberati4, Danka Grčević6,9, Maša Filipović6,9, Ciro Menale7, Eleonora Palagano8, Barbara Bottazzi4, Alberto Mantovani1,4,10, Cristina Sobacchi3, and Antonio Inforzato1,4
12:45 PM - 01:00 PM
28
Memory T cells impair progenitor and endothelial cell behavior during fracture healing via secretion of interleukin 5
Christian H Bucher1,2, Marie A Mohn1, Hans-Dieter Volk2,3, Georg N Duda1,2, and Katharina Schmidt-Bleek1,2
01:00 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:00 PM
Guided Tour of Ancient Corinth (Buses Depart from Hotel Lobby)
08:00 PM - 11:00 PM
Dinner and Informal Discussions (Buses do not return or pickup from the hotel prior to dinner)

Friday, May 31

08:00 AM - 09:00 AM
Breakfast
Session VII: Aging and rejuvenating the osteoimmune system-2
Chairs: Mary Nakamura and Masayuki Tsukasaki
09:00 AM - 09:30 AM
29
Barriers to immune defense against new infections with aging
Janko Ž. Nikolich
09:30 AM - 10:00 AM
30
Targeting energy metabolic pathways as therapeutic intervention for osteoporosis
Ha-Neui Kim
10:00 AM - 10:30 AM
31
Tissue resident monocytic cells act as guardian for the synovium
Harrs Perlman
10:30 AM - 10:50 AM
32
Inflammation and osteoblastic differentiation govern the commitment of hBMSCs toward bone regeneration
Nathalie Chevallier1, Laura Coquelin1, Gabriel Windels1, Luciano Vidal4, Nora El Jahrani1, Mathieu Manassero4, Cecile Lefevre3, and Hakim Hocini3
10:50 AM - 11:10 AM
33
De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
Luca F Sandor1, Joon B Huh1, Peter Benko1, Toru Hiraga2, Szilard Poliska3, Csaba Dobo-Nagy4, Joanna P Simpson5, Natalie ZM Homer6, Bidesh Mahata7, and David S Gyori1
11:10 AM - 11:30 AM
Coffee Break and Poster Viewing
Session VIII: Upcoming
Chairs: Mary Nakamura and Masayuki Tsukasaki
11:30 AM - 11:45 AM
34
Biomaterial-modulated osteoclastogenesis in bone regeneration
Liline Fermin1, Daniel de Melo Pereira1,2, Huipin Yuan3, Noel Davison1,2, Elizabeth Rosado Balmayor4, Pamela Habibovic1, and Zeinab Tahmasebi Birgani1
11:45 AM - 12:00 PM
35
Osteoimmunology: why peri-implantitis should be regarded as an immune disease
Joseph Choukroun
12:00 PM - 12:15 PM
36
B cells regulate bone remodeling in a Fra-2/AP-1 dependent manner
Bettina Groetsch, Xianyi Meng, Flora Nguemedjio Foko, Sylvia Thiele, Martina Rauner, Georg Schett, and Aline Bozec
12:15 PM - 12:30 PM
37
Estrogen loss postpartum activates low grade chronic inflammation: Implications and consequences
Rajeev Aurora1, Leah A Hong2, Emily W Zantow2, Di Wu1, Samantha Cooke1, and Amit Mathur3
12:30 PM - 12:45 PM
38
The NLRP3 inflammasome is tightly regulated in the osteoclast cell lineage to avoid unnecessary osteolysis
Khushpreet Kaur1, Yael Alippe5, Chun Wang1, Nicholas Semenkovich2, Kunjan Khanna3, Saumya Bhagat1, Timothy Peterson4, Yousef Abu-Amer3, Roberta Faccio3, and Gabriel Mbalaviele1
12:45 PM - 01:00 PM
39
Immunization-induced immune experience leads to altered local peptide patterns in bone and modulates fracture healing
Ann-Kathrin Mess
01:00 PM - 01:15 PM
40
Retrotransposon-derived dsRNAs trigger osteoblast mineralization via a paracrine, PKR-mediated, sterile inflammatory response
Arianna Mangiavacchi1, Gabriele Morelli1, Sjur Reppe2, Benjamin Eggerschwiler5, Peng Liu1, Alfonso Saera6, Elisa Casanova10, Huoming Zhang7, Dalila Bensaddek7, Mirko Celii1, Carolina Gomez8, Vid Prijatelj8, Francesco Della Valle1, Nazerke Atinbayeva1, Juan Carlos Izpisua Belmonte9, Fernando Rivadeneira8, Paolo Cinelli4, Kaare Morten Gautvik3, and Valerio Orlando1
01:15 PM - 01:30 PM
41
Notch signaling modulates human osteoclast progenitor differentiation and activity in patients with rheumatoid arthritis
Alan Sucur1, Sara Anicic1, Zrinka Jajic2, Marina Ikic Matijasevic3, Mariastefania Antica4, Masa Filipovic1, Ivo Kresic5, Tomislav Kelava1, Nataša Kovačić6, and Danka Grcevic1
01:30 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:30 PM
Farewell Dinner

Saturday, June 01

08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure