17th International Conference on Innate Immunity

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  
    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 
    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport
    You want to arrive at the Ioannina Airport (code: IOA) and take a taxi from the airport to the hotel (~20 EUR)

    Accommodation Tax
    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations
    Accommodations for the conference are at the Hotel Du Lac.  The hotel is located in the city of Ioannina, 7 km from the Airport. 

    Arrival and Check-in
    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue
    The Du Lac Conference Center is located at the hotel. 

    Handicapped Accessibility
    The site is fully handicapped accessible.

    Oral Presentations
    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour
    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast
    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions
    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions
    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer
    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation
    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information
    Animals are not permitted on site.
    Badges are required for admission to all events.
    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices
    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 
    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Saturday, July 09

07:00 PM - 08:00 PM
Conference Registration
08:00 PM - 10:30 PM
Welcome Reception and Dinner

Sunday, July 10

07:30 AM - 08:30 AM
Breakfast
08:30 AM - 08:45 AM
Welcome and Opening Remarks (Organizing Committee)
Cancer
Chairs: Roxane Tussiwand and Dimitris Kontoyiannis
08:45 AM - 09:10 AM
New tools to prevent cancer growth and spread: a 'Clever' approach
Sirpa Jalkanen
09:10 AM - 09:35 AM
An innate role of cancer associated fibroblasts in tumor immune evasion
Panayotis Verginis
09:35 AM - 10:00 AM
Myeloid control of anti-tumor immunity in colorectal cancer
Sebastian Zeissig
10:00 AM - 10:25 AM
Stratification of the liver micro-environment: consequences for liver cancer treatment
Mathias Heikenwälder
10:25 AM - 10:50 AM
Clonal expansion and epigenetic inheritance shape long-lasting NK cell memory
Chiara Romagnani
10:50 AM - 11:10 AM
Neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes at the early stage of cancer
Ekaterina Pylaeva, Maksim Domnich, Georg Korschunow, Elena Siakaeva, Stephan Lang, and Jadwiga Jablonska
11:10 AM - 12:00 PM
Coffee Break and Poster Sessions
Immunometabolism
Chairs: Shabaana A. Khader and Liwu Li
12:00 PM - 12:25 PM
Immunometabolic regulation of resolution of inflammation
Triantafyllos Chavakis
12:25 PM - 12:50 PM
Hypoxia and nutrient availability sustain reprogramming of the innate immune response
Sarah Walmsley
12:50 PM - 01:15 PM
Reprogramming myeloid cell metabolism reverses cognitive decline in aging
Katrin Andreasson
01:15 PM - 01:40 PM
Immunological anti-ferroptosis
Peter Murray
01:40 PM - 02:05 PM
Metabolic control of disease tolerance to infection
Miguel Soares
02:05 PM - 03:30 PM
Lunch and Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions

Monday, July 11

08:00 AM - 09:00 AM
Breakfast
Trained Immunity
Chairs: Triantafyllos Chavakis and Miguel Soares
09:00 AM - 09:25 AM
Trained immunity: from basic mechanisms to vaccination
Mihai Netea
09:25 AM - 09:50 AM
Maladaptive innate immune training of bone marrow myelopoiesis links inflammatory comorbidities
Xiaofei Li1, Hui Wang1, Xiang Yu2, Gundappa Saha1, Lydia Kalafati3, Charalampos Ioannidis3, Ioannis Mitroulis3, Mihai Netea4, Triantafyllos Chavakis3, and George Hajishengallis1
09:50 AM - 10:15 AM
Innate immune memory dynamics of monocyte exhaustion and resolution
Liwu Li
10:15 AM - 10:40 AM
Mimicking Trained Immunity Through Molecular Signals of Calorie Restriction: Novel Strategies to Control MTB Infection
Carla Palma1 and Giuseppe Matarese2
10:40 AM - 11:00 AM
Innate immune training of granulopoiesis: A novel tool in cancer immunotherapy
Lydia Kalafati1, Ioannis Kourtzelis3, Aikaterini Hatzioannou1, Mihai Netea4, George Hajishengalis4, Ioannis Mitroulis6, Panayotis Verginis4, and Triantafyllos Chavakis1
11:00 AM - 12:00 PM
Coffee Break and Poster Viewing
Infection and Immunity
Chairs: Niki Moutsopoulos and Giuseppe Matarese
12:00 PM - 12:25 PM
The power of one: What we learned about the innate immune system in COVID-19
Joachim Schultze
12:25 PM - 12:50 PM
Therapeutic complement modulation in severe COVID-19: Novel insights, challenges and opportunities
Dimitrios Mastellos1, Panagiotis Skendros2, Konstantinos Ritis2, and John Lambris3
12:50 PM - 01:15 PM
Type I and type III interferons in antiviral immunity to COVID-19: A balancing act
Evangelos Andreakos
01:15 PM - 01:40 PM
Understanding the lung landscape during tuberculosis
Shabaana Khader
01:40 PM - 02:05 PM
Reproducible research and scientific publishing in 2022
John Ioannides
02:05 PM - 03:30 PM
Lunch and Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions

Tuesday, July 12

08:00 AM - 09:00 AM
Breakfast
Mucosal Immunity
Chairs: Georgios Hajishengallis and Panagiotis Verginis
09:00 AM - 09:25 AM
Mechanisms that govern dissemination of microbial or inflammatory signals from the ileum
Gwen Randolph
09:25 AM - 09:50 AM
Group 3 innate lymphoid cells instruct cryptopatch-associated dendritic cells establishing a checkpoint for metabolic homeostasis
Andreas Diefenbach
09:50 AM - 10:15 AM
Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier.
Niki Moutsopoulos
10:15 AM - 10:40 AM
The new kid on the block: Neutrophils in alveolar macrophage ontogeny
Maziar Divangahi
10:40 AM - 11:05 AM
Ab-AIRE-ant response: Autoimmunity, IFN, STAT1, and mucosal candidiasis
Michail Lionakis, Vasileios Oikonomou, and NIki Moutsopoulos
11:05 AM - 12:00 PM
Coffee Break and Poster Viewing
Host response regulation
Chairs: Irina Udalova and Peter Murray
12:00 PM - 12:25 PM
Mesenchymal cell regulation of inflammatory arthritis
Markus Hoffmann
12:25 PM - 12:50 PM
Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors
Roxane Tussiwand1, Fabian Klein2, Julien Roux2, and Grozdan Cvijetic1
12:50 PM - 01:15 PM
Maintenance of epigenetic macrophage identity through expansion in long term culture
Michael Sieweke
01:15 PM - 01:35 PM
Semaphorin 4A/Plexin D1 signaling in the bone marrow niche suppresses myeloid-driven inflammation by restraining activation of myeloid-biased HSC
Lev Silberstein 1, Dorsa Toghani 1, Edie Crosse1, Amogh Pradeep 1, Elmir Mahammadov3, Antonio Scialdone 3, Negar Seyedhassantehrani 3, Christian Burns3, and Joel Spencer3
01:35 PM - 01:50 PM
IL-1RAcP: A central mediator in mucosal Candida immunity
James Griffiths1, Natalia Kotowicz1, Giorgio Camilli1, Adrian Lau1, Thomas Ap Rees1, Sarah Gaffen2, and Julian Naglik1
01:50 PM - 02:05 PM
Severe COVID-19 is marked by a dysregulated myeloid cell compartment
Jonas Schulte-Schrepping1,2, Elise Gressier3, Nico Reusch1,2, Daniela Paclik4, Kevin Baßler1,2, Stephan Schlickeiser4, Bowen Zhang5, Benjamin Krämer6, Tobias Krammer7, Sophia Brumhard8, Lorenzo Bonaguro1,2, Elena De Domenico1, Daniel Wendisch8, Anna Aschenbrenner2,9, Yang Li5,9, Jacob Nattermann6,10, Birgit Sawitzki4, Antoine-Emmanuel Saliba7, Sammy Bedoui3, Leif Sander8,11, and Joachim Schultze1,2
02:05 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour
07:30 PM - 10:30 PM
Dinner and Informal Discussions

Wednesday, July 13

08:00 AM - 09:00 AM
Breakfast
Myeloid cells and inflammation
Chairs: Mihai Netea and Katrin Andreasson
09:00 AM - 09:25 AM
Neutrophils activation as the bottleneck of intestinal inflammation
Irina Udalova
09:25 AM - 09:50 AM
Macrophages as gate keepers of inflammation
Gerhard Krönke
09:50 AM - 10:15 AM
Investigating the relevance of hepatic macrophage plasticity across distinct inflammatory conditions.
Christian Zwicker, Anna Bujko, Anneleen Remmerie, Federico De Ponti, Kathryn Waller, Paul Collins, Pieter Louwe, Bavo Vanneste, Fleur Parmentier, Tinne Thoné, Liesbet Martens, Mushida Binte Abdul Latib, and Charlotte Scott
10:15 AM - 10:40 AM
hnRNPD as a regulator of proinflammatory to proangiogenic macrophage transitions
Sofia Gargani1,2, Fotis Ioakeimidis1, Niki Lourou1,2, Christina Arapatzi1, Dimitris Tzanos1, Marania Saridaki1, Esmeralda Dushku2, Margarita Chatzimike1, Nikolaos Sidiropoulos2, Margarita Andreadou1, Vassileios Ntafis1, Pantelis Hatzis1, Vassiliki Kostourou1, and Dimitris Kontoyiannis1,2
10:40 AM - 11:00 AM
Selective reprogramming of macrophages by IFN-gamma during acute Toxoplasma gondii Infection
Felix Yarovinsky, Andrew Martin, Shilpi Giri, Alexandra Safronova, and Samantha Kwok
11:00 AM - 12:00 PM
Coffee Break and Poster Viewing
Innate immunity topics
Chairs: Sirpa Jalkanen and Michail Lionakis
12:00 PM - 12:25 PM
Neutrophil heterogeneity in tumor
Ng Guan
12:25 PM - 12:40 PM
Macrophage diversity in cancer revisited in the era of single cell omics
Bin-Zhi Qian1,2,3, Ruo-Yu Ma1, and Annabel Black3
12:40 PM - 12:55 PM
Human serum amyloid A enhances the immune response of phagocytic cells in tuberculosis.
Malwina Kawka1, Bożena Dziadek1, Renata Płocińska2, Przemysław Płociński2, Anna Brzostek2, and Jarosław Dziadek2
12:55 PM - 01:10 PM
CTLA-4 Polymorphisms: Influence on Relapse and Survival in Children undergoing allogeneic hematopoietic Stem Cell Transplantation
Bernd Gruhn, Susan Wittig, and Judith Hammrich
01:10 PM - 01:25 PM
Activation of type 2 innate immune system in old age
Tommy Terooatea2, Yasutaka Motomura2, Natsuko Otaki2, Natsuki Takeno2, Haruka Yabukami2, Kazuyo Moro2, and Aki Minoda2
01:25 PM - 01:40 PM
Kupffer cell survival is critical to prevent exacerbated anti-microbial immune responses
Christian Zwicker1,2, Anneleen Remmerie1,2, Tinne Thoné1,2, Liesbet Martens1,2, Bavo Vanneste1,2, Fleur Parmentier1,2, and Charlotte Scott1,2
01:40 PM - 01:55 PM
MS4A genes, patterns of pathological deregulation in innate immunity
Sarah Mapelli1, Ana Gomes1, Barbara Bottazzi1, and Alberto Mantovani1,2
01:55 PM - 02:00 PM
Closing Remarks
02:00 PM - 03:30 PM
Lunch and Informal Discussions
08:00 PM - 11:30 PM
Farewell Dinner

Thursday, July 14

08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure