10th International Conference on Autoimmunity: Mechanisms and Novel Treatments

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 

    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport

    Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.

    Accommodation Tax

    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations

    Accommodations for the conference are at the Avra Imperial Hotel.  The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Avra Imperial Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour

    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast

    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Thursday, October 20

06:00 PM - 07:00 PM
Conference Registration
07:00 PM - 10:00 PM
Welcome Reception and Dinner

Friday, October 21

08:00 AM - 09:00 AM
Breakfast
09:00 AM - 09:05 AM
Welcome and Opening Remarks
T cell differentiation (and gd T cells)
Chairs: Ludger Klein and Dario Vignali
09:05 AM - 09:30 AM
1
Roads to memory: Studying the regulation of lymphocyte stemness by mapping the fate of single T cells
Lorenz Kretschmer1, Carlson Tsui2, Simon Grassmann1, Marten Plambeck1, Atefeh Kazeroonian1, Lorenz Mihatsch1, Svenja Rapelius1, Michael Flossdorf1, Dirk H Busch1, Axel Kallies2, and Veit R Buchholz1
09:30 AM - 09:55 AM
2
Determinants of central T cell tolerance
Ludger Klein, Iliana Siamishi, Joao Freitas, Dario Zebcevic, and Amina Sayed
09:55 AM - 10:20 AM
3
Innate and adaptive γδ T cells
Immo Prinz
10:20 AM - 10:45 AM
4
Targeting mitochondrial metabolism to influence T cell differentiation and function
Tim Sparwasser
10:45 AM - 11:10 AM
5
Autoreactive CD8+ T cells: impact of exhaustion and LAG3
Dario AA Vignali
11:10 AM - 12:00 PM
Coffee Break and Poster Viewing
T cell - B cell interactions
Chairs: Lucy Walker and Jessica Hamerman
12:00 PM - 12:25 PM
6
COMPLEXity of antibody-induced IFN in lupus, it’s not all IgG
Jessica Hamerman
12:25 PM - 12:50 PM
7
A role for IL-4 in germinal center selection
Marion Pepper
12:50 PM - 01:15 PM
8
Lessons from inborn errors of immunity that increase susceptibility to human lupus
Carola G Vinuesa
01:15 PM - 01:40 PM
9
Targeting the Achilles heel of costimulation blockade in autoimmunity
Lucy S.K. Walker
01:40 PM - 01:55 PM
10
T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity
Anna Kolz1, Anneli Peters1,2, Isabel Bauer1, Eduardo Beltran1, and Naoto Kawakami1
01:55 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions (Buses depart from Hotel Lobby)

Saturday, October 22

08:00 AM - 09:00 AM
Breakfast
Neuroinflammation
Chairs: Roland Liblau and Alexander Flügel
09:00 AM - 09:25 AM
11
Regulatory plasma cells: A novel cure for established for ongoing CNS autoimmunity
Simon Fillatreau
09:25 AM - 09:50 AM
12
The lung–brain axis in CNS autoimmunity
Alexander Flügel1, Leon Hosang1, Roger Cugota Canals1, Felicia Joy van der Flier1, Jacqueline Hollensteiner3, Rolf Daniel3, and Francesca Odoardi1,
09:50 AM - 10:15 AM
13
Tissue-resident T cells in CNS inflammatory diseases: present at the crime scene and …guilty
Roland S LIBLAU
10:15 AM - 10:30 AM
14
Identification of essential modules regulating T cell migration to the central nervous system in multiple sclerosis
Arek Kendirli1, Clara de la Rosa1, Katrin Franziska Lämmle1, Klara Magdalena Eglseer 1, Isabel Julia Bauer 1, Vladyslav Kavaka1, Stephan Winklmeier 1, Christian Wichmann 2, Lisa-Ann Gerdes1, Tania Kümpfel1, Klaus Dornmair 1, Eduardo Beltrán 1, Martin Kerschensteiner1, and Naoto Kawakami1
10:30 AM - 11:30 AM
Coffee Break and Poster Viewing
Microbiome
Chairs: Jen Gommerman and Francisco Quintana
11:30 AM - 11:55 AM
15
The maternal microbiota shapes susceptibility to Type 1 Diabetes
Markus B Geuking1, Carolyn A Thomson2, and Kathy D McCoy2
11:55 AM - 12:20 PM
16
The gut microbiome in multiple sclerosis: from observations to mechanisms
Sergio Baranzini
12:20 PM - 12:45 PM
17
The role of the microbiome and microbial-derived metabolites in immune regulation
Kathy D. McCoy
12:45 PM - 01:10 PM
18
Integration of Retinoic Acid and Lymphotoxin signals for maintenance of mucosal versus splenic dendritic cells
Jennifer Gommerman
01:10 PM - 01:25 PM
19
Metabolite-triggered release of TNF by liver-resident CXCR6 CD8 T cell mediates immune pathology in fatty liver disease
Michael Dudek1, Dominik Pfister2, Sainitin Donakonda1, Pamela Filpe3, Annika Schneider1, Melanie Laschinger1, Daniel Hartmann1, Norbert Hüser1, Philippa Meiser1, Felix Bayerl1, Donato Inverso2, Jennifer Wigger3, Marcial Sebode3, Rupert Öllinger1, Silke Hegenbarth1, Danijela Heide2, Florian Müller2, Pierluigi Ramadori2, Simon Reider4, Herbert Tilg4, Maria Effenberger4, Susanne Roth5, Adrian Billeter5, Beat Müller-Stich5, Percy Knolle1,6, Jan-Philipp Malm2, and Roland Rad1
01:25 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions (Buses depart from Hotel Lobby)

Sunday, October 23

08:00 AM - 09:00 AM
Breakfast
Helper T cells
Chairs: Thomas Korn and Nicole Joller
09:00 AM - 09:25 AM
20
Skin and gut imprinted T helper cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity
Thomas Korn
09:25 AM - 09:50 AM
21
Viral infections license T helper cells for antigen-independent recruitment and activation
Nikolas Rakebrandt1, Seyed Nima Yassini1, Anna Kolz2, Anneli Peters2, and Nicole Joller1
09:50 AM - 10:15 AM
22
MicroRNA-mediated regulation of the pathogenicity of effector CD4+ T helper subsets in autoimmune pathology
Bruno Silva-Santos
10:15 AM - 10:40 AM
23
Role of the transcription factor Eomes in Neuroinflammation
Anne Dejean
10:40 AM - 10:55 AM
24
New implications for IRF5 in T cell-mediated autoimmunity
Betsy J Barnes
10:55 AM - 11:30 AM
Coffee Break and Poster Viewing
Mononuclear phagocytes
Chairs: Melanie Greter and Burkhard Becher
11:30 AM - 11:55 AM
25
IFN-γ and GM-CSF control complementary differentiation programs in the monocyte to phagocyte transition during tissue inflammation
Burkhard Becher
11:55 AM - 12:20 PM
26
CNS macrophages and the blood-brain barrier
Melanie Greter
12:20 PM - 12:45 PM
27
Heterogeneity of Resident Tissue Macrophages (RTMs)
Florent Ginhoux
12:45 PM - 01:10 PM
28
Astrocyte cell-cell communication in health and disease
Francisco J Quintana
01:10 PM - 01:25 PM
29
Deciphering the ontogeny and role of fetal macrophages at the blood-placental barrier
Elsa Marie Dolores ROUSSEL
01:25 PM - 01:40 PM
30
GM-CSF maintains a CD226+ subset of salivary gland tissue resident macrophages during postnatal development
Frederike Ridder, Selma Tuzlak, Myrto Andreadou , Rachel Lindemann, Donatella DeFeo, Melanie Greter, and Burkhard Becher
01:40 PM - 03:00 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour (Buses depart hotel lobby)
07:30 PM - 10:30 PM
Dinner and Informal Discussions (Buses do not return to hotel prior to dinner)

Monday, October 24

08:00 AM - 09:00 AM
Breakfast
Regulatory and exhausted T cells
Chairs: Adrian Liston and Immo Prinz
09:00 AM - 09:25 AM
31
Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism
Axel Kallies
09:25 AM - 09:50 AM
32
Notch signals in recent thymic emigrant regulatory T cell maturation and functionality
JC Zuniga-Pflucker
09:50 AM - 10:15 AM
33
Synthetic delivery of IL2 expands the brain regulatory T cell population and effectively prevents pathological neuroinflammation
Adrian Liston
10:15 AM - 10:40 AM
34
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation
Pascale Zwicky1, Florian Ingelfinger1, Bruno M Silva de Melo1, Fiorella Ruchti2, Stefanie Schärli1, Nicole Puertas1, Mirjam Lutz1, San P Truong3, Thomas M. Kündig4, Mitchell P Levesque4, Julia-Tatjana Maul4, Christoph Schlapbach5, Salomé LeibundGut-Landmann2, Sarah Mundt1, and Burkhard Becher1
10:40 AM - 11:30 AM
Coffee Break and Poster Viewing
Lymphatics and barrier-associated cells in immunity
Chairs: Francesca Odoardi and Ari Waisman
11:30 AM - 11:55 AM
35
Inflammatory mediators of the blood barrier permeability
Ari Waisman
11:55 AM - 12:20 PM
36
Immunomodulatory functions of lymphatic vessels
Stephanie Hugues
12:20 PM - 12:45 PM
37
Role of the meninges in CNS autoimmunity
Francesca Odoardi
12:45 PM - 01:10 PM
38
Investigating commensal-specific immunity in barrier tissues
Oliver Harrison
01:10 PM - 01:35 PM
39
Maladaptive inflammatory memory in hematopoietic progenitors underlies the comorbidity of rheumatoid arthritis and periodontal disease
Xiaofei Li1, Hui Wang1, Xiang Yu2, Gundappa Saha1, Lydia Kalafati3, Charalampos Ioannidis3, Ioannis Mitroulis3, Mihai Netea4, Traintafyllos Chavakis3, and George Hajishengallis1
01:35 PM - 01:45 PM
Closing Remarks
01:45 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discusssions
07:30 PM - 11:00 PM
Farewell Dinner

Tuesday, October 25

08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure