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Aegean Conferences Communication
Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences
Registration
In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.
Airport
Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.
Accommodation Tax
An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts.
Accommodations
Accommodations for the conference are at the Avra Imperial Hotel. The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center. Please take a taxi from the airport to the conference venue.
Arrival and Check-in
It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.
Conference Venue
The Avra Imperial Conference Center is located at the hotel.
Handicapped Accessibility
The site is fully handicapped accessible.
Oral Presentations
Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session. The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.
City Tour
Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation.
Breakfast
Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program.
Lunches/Informal Discussions
Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.
Dinners/Informal Discussions
Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting. Please contact info@aegeanconferences.org.
Internet, Phone, & Computer
Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.
Certificate of Participation
A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session.
Passports and Visa
Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.
Letters of Invitation
Letters of invitation to attend an Aegean Conference meeting will be issued only to:
- Authors of accepted abstracts
- Fully paid registrants
Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.
Liability and Insurance
Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.
Other Information
Animals are not permitted on site.
Badges are required for admission to all events.
All Aegean Conferences events are non-smoking.
No Photographs and Recording Devices
Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations.
Code of Conduct Policy
Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here.
Thursday, May 19
07:00 PM - 08:00 PM
Conference Registration
08:00 PM - 10:30 PM
Welcome Reception and Dinner
Friday, May 20
07:30 AM - 08:30 AM
Breakfast
08:20 AM - 08:30 AM
Introductory Remarks - Leonidas Platanias
Chairs: Lopa Mishra and Diana Saleiro
08:30 AM - 08:55 AM
1
Novel tumor promoting activities of CD95/Fas in breast cancerAbdul S. E Qadir11, Jean Philippe Guégan3, Christophe Ginestier4, Assia Chaibi3, Alban Bessede3, Emmanuelle Charafe-Jauffret4, Manon Macario4, Vincent Lavoué5, Thibault de la Motte Rouge6, Hongbin Wang7, Emily Stroup7, Andrea E. Murmann1, Zhe Ji7, Patrick Legembre, and Marcus E. Peter1
08:55 AM - 09:20 AM
2
A TGFβ-ALDH2 Axis controls Obesity-Associated Liver Disease and CancerShuyun Rao1, Xiaochun Yang9, Xiyan Xiang9, Kazufumi Ohshiro1, Sobia Zaidi9, Krishanu Bhowmick9, Richard Amdur3, Ben L Da1, James M Crawford4, Bibhuti Mishra5, Herbert Yu6, Patricia S Latham7, Xin Wei Wang8, Adrian R Krainer2, Nancy R Gough1, and Lopa Mishra9
09:20 AM - 09:45 AM
3
The role of long noncoding lincRNA Platr18 in TGFbeta-mediated breast cancer progression. Philip H Howe
09:45 AM - 10:10 AM
4
PTPs and STATs in Cancer ImmunotherapyTony Tiganis
10:10 AM - 10:30 AM
5
How Transforming Growth Factor beta (TGF-β) is Activated in the Tumors ?Alexandra Lainé1, Ossama labiad1, Hector Hernandez-Vargas1, Helena Paidassi3, Mark Travis4, Dean Sheppard2, and Julien C. Marie1
10:30 AM - 11:00 AM
Coffee Break and Posters Viewing
Fundamentals and unexpected angles
Chairs: Jadwiga Jablonska and Elena Voronov
11:00 AM - 11:25 AM
6
Cytokine receptor Stoichiometry regulates cell signalling and functionAngel F Lopez
11:25 AM - 11:50 AM
7
Structural Rearrangements of Chromatin during Transcriptional Activation of Interferon-Induced GenesThomas Decker
11:50 AM - 12:15 PM
8
Exploring shared immune mechanisms in cancer and COVID-19Ludmila Prokunina-Olsson
12:15 PM - 12:40 PM
9
SARS-CoV-2: variant predictions and antiviral drug design are enabled by in vitro evolutionGideon Schreiber
12:40 PM - 01:05 PM
10
IFNs-α, COVID-19 and cancerEleanor Fish
01:05 PM - 01:25 PM
11
IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.Tommaso Virgilio1, Alberto Arribas2, Robert E Hunger3, Antonino Bruno6, Lorenzo Mortara5, Elena Voronov4, Silvia Monticelli1, Ron N Apte4, Francesco Bertoni2, and Santiago F. Gonzalez1
01:25 PM - 01:45 PM
12
Effects of clonal hematopoiesis on anti-tumor immunity: PPM1D-driven clonal hematopoiesisOleg N Demidov
01:45 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:30 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions
Saturday, May 21
07:30 AM - 08:20 AM
Breakfast
08:20 AM - 08:30 AM
Housekeeping Notes
Chairs: Elenore Fish and Ana Gamero
08:30 AM - 08:55 AM
13
Cytokines and microbiota in inflammation, cancer progression and metastasisSergei Grivennikov
08:55 AM - 09:20 AM
14
Activation of cyclin D1-NF-kB and inactivation of PTEN drives development of endometrial carcinomaJ. Alan Diehl
09:20 AM - 09:45 AM
15
Growth Hormone Receptor (GHR) signalling in melanoma progression and immune evasionAndrew Brooks
09:45 AM - 10:10 AM
16
Pro-inflammatory activity of STAT2 in the gastrointestinal tractAna Gamero
10:10 AM - 10:30 AM
17
A STAT5B–CD9 axis determines self-renewal in hematopoietic and leukemic stem cellsSebastian Kollmann
10:30 AM - 11:00 AM
Coffee Break and Poster Viewing
Chairs: Katherine Borden and Iris Behrman
11:00 AM - 11:25 AM
18
Interferon-gamma promotes melanoma progression and metastasisBo Zhou, Jayati Basu, Hasan R Kazmi, Sarah Preston-Alp, Xuan Mo, and M. Raza Zaidi
11:25 AM - 11:50 AM
19
STAT1 signalling in myeloid cells regulates hematopoietic progenitors in the spleen during infection and inflammationTanja Bulat1, Svetlana Pahernik1, Caroline Lassnig1,3, Jelena Josipović1, Lena Amenitsch1, Dagmar Gotthardt2, Veronika Sexl2, Mathias Müller1,3, and Birgit Strobl1
11:50 AM - 12:15 PM
20
The role of tumor-related and microenvironment IL-1α in TNBC progressionMathumathi Krishnamohan, Sapir Maudi Boker, Irena Kaplanov, Esther Noy Machluf, Marina Bersudsky, Ron N Apte, Alex Braiman, and Elena Voronov
12:15 PM - 12:40 PM
21
Signal transduction of IL-6-type cytokines: involvement of (short and long) non-coding RNAs Nadège W.E. Minoungou1, Mélanie Kirchmeyer1, Florence A. Servais1, Petr V. Nazarov2, Aurélien Ginolhac1, Stephanie Kreis1, Claude Haan1, and Iris Behrmann1
12:40 PM - 01:05 PM
22
Role of SOCS3 and SHP2 for the Robustness and Information Transfer
within IL-6-induced JAK/STAT Signalling
Anna Dittrich1, Jessica Fiebelkow1, Beate Gündel1, André Gündel2, Nora Mehwald1, Ulrike Billing1, Tomasz Jetka3, Lukas Nordmann1, Nicole Wundrack1, Michal Komorowski3, Steffen Waldherr4, and Fred Schaper1
01:05 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
City Tour and Discussions
07:00 PM - 10:00 PM
Dinner and Informal Discussions
Sunday, May 22
07:30 AM - 08:20 AM
Breakfast
08:20 AM - 08:30 AM
Housekeeping Notes
Tumor microenvironment and immune responses-1
Chairs: Stephanie Watowich and Anna Bielawska
08:30 AM - 08:55 AM
23
Co-opting the innate and adaptive immune system for potent antitumor and antiviral activityBryan R.G. Williams1, Himanshu Brahmbhatt, and Jennifer MacDiarmid
08:55 AM - 09:20 AM
24
Interferons generate a distinct subset of activated dendritic cells in the tumor microenvironment.Malay Haldar and Tsun Ki Jerrick To
09:20 AM - 09:45 AM
25
IFN-deficiency modulates neutrophil development and tumorigenic properties Jadwiga Jablonska
09:45 AM - 10:10 AM
26
BTN2A1 is essential for the activation of Vγ9Vδ2+ T cellsAndreas Behren1,2, Marc Rigau3,4,5, Simone Ostrouska1,2, Darryl N. Johnson3,5, Hamish E.G. McWilliam3,6, Jose A. Villadangos3,6, Andrew Hammet7, Anne M. Verhagen7, Eugene Maraskovsky7, Con Panousis7, Jonathan Cebon1,2, Dale I. Godfrey3,5, Adam P. Uldrich3,5, and Thomas S. Fulford3
10:10 AM - 10:30 AM
27
Interleukin-11 as a therapeutic target to control oncogenic Stat3 signalingMatthias Ernst
10:30 AM - 11:00 AM
Coffee Break and Poster Viewing
Tumor microenvironment and immune responses-2
Chairs: Veronika Sexl and Tanja Bulat
11:00 AM - 11:25 AM
28
Inactivation of the Type I IFN pathway in the intratumoral cytotoxic T lymphocytesSerge Y Fuchs
11:25 AM - 11:50 AM
29
The role of cytokines bound to extracellular vesicles in cancer and metastasisAndreas Moeller
11:50 AM - 12:15 PM
30
Towards an understanding of the STAT5BN642H driver mutation in blood cancers and how to eliminate itRichard Moriggl
12:15 PM - 12:40 PM
31
The diverse oncogenic impact of STAT3 in cancer Jesse Balic, Mohamed Saad, Louise McLeod, Beena Kumar, Sultan Alhayyani, Prithi Bhathal, Richard Ferrero, Dan Gough, and Brendna Jenkins
12:40 PM - 01:05 PM
32
STAT3 deletion increases metastatic dissemination of Small Cell Lung CancerDaniel J Gough
01:05 PM - 01:25 PM
33
Continuous sensing of IFNα by liver sinusoidal endothelial cells shapes a vascular antimetastatic barrierGiovanni Sitia1, Ngoc Lan Tran1, Lorena Maria Ferreira1, Blanca Alvarez-Moya1, Valentina Buttiglione1, Barbara Ferrini1, Paola Zordan1, Eugenia Bezzecchi2, Giulia Maria Scotti2, Antonio Esposito3, Riccardo Leone3, Andrea Monestiroli1, Claudio Fagioli1, Andrea Brendolan4, and Luca G. Guodotti1
01:25 PM - 01:50 PM
34
Boosting metastatic cell immunogenicity via therapeutic restoration of intratumoral IFNs Belinda Parker
01:50 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions
Monday, May 23
07:30 AM - 08:20 AM
Breakfast
08:20 AM - 08:30 AM
Housekeeping Notes
Pathogenesis and therapies-1
Chairs: Hua Yu and Natalia Bednarz-Knoll
08:30 AM - 08:55 AM
35
Prolactin-humanized NSG mice for improved in vivo modeling of human cancer and tissuesHallgeir Rui
08:55 AM - 09:20 AM
36
Melanoma Addiction to GCDH ZEEV RONAI and Sachin Verma
09:20 AM - 09:45 AM
37
STAT3 and STAT5 gain-of-function mutations in hematopoietic malignanciesVeronika Sexl
09:45 AM - 10:10 AM
38
STAT3: from fundamental discoveries to clinical translationHua Yu
10:10 AM - 10:30 AM
39
ULK1 as a novel therapeutic target in melanomaDiana Saleiro, Sarah E Fenton, Liliana Ilut, Mariafausta Fischietti, Markella Zannikou, Chidera V Oku, and Leonidas C Platanias
10:30 AM - 11:00 AM
Coffee Break and Poster Viewing
Pathogenesis and therapies-2
Chairs: Bryan Williams and Ludmila Prokunina-Olsson
11:00 AM - 11:25 AM
40
Mechanisms of immune toxicity in checkpoint blockade therapyStephanie S Watowich
11:25 AM - 11:50 AM
41
Cancer cells hijack RNA processing to transform cell architecture inside and outMehdi Ghram, Jean-Clement Mars, Gavin Morris, Biljana Culjkovic, and Katherine LB Borden
11:50 AM - 12:15 PM
42
Interferon signaling circuits as targets in the treatment of malignanciesLeonidas Platanias
12:15 PM - 12:35 PM
43
STAT3 signaling as a checkpoint for epigenetic reprogramming of acute myeloid leukemia into antigen-presenting cells Marcin Kortylewski
12:35 PM - 12:55 PM
44
Loss of tumour-intrinsic type I IFN signalling predicts and facilitates bone-metastatic outgrowth in advanced prostate cancerKatie L Owen1,7, Linden J Gea2, Aaron Meyers1, Niall Corcoran4,5, Paul Hertzog2,3, Chris Hovens4, Shahneen Sandhu6,7, and Belinda S Parker1,7
12:55 PM - 01:15 PM
45
Clinical Development of heterodimeric IL-15 for Cancer ImmunotherapyGeorge N Pavlakis
01:15 PM - 01:20 PM
Concluding Remarks - Serge Fuchs
01:15 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 08:00 PM
Informal Discussions
08:00 PM - 11:30 PM
Farewell Dinner - Leonidas Platanias - Travel awards presentation
Tuesday, May 24
08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure