20th International Conference on Innate Immunity

Posters

Important: The program online is copyrighted to each author and should not be copied and pasted!
46 Mediators of the inflammatory response at the maternal- fetal interface: In vitro experimental study of bacterial infection, isolated or in combination with Mycoplasma hominis, in immortalized epithelial amniotic cells.
Geovanna Cristofani Cursino, Vitória Carvalho Troitiño, Marcel Rodrigues Ferreira, Giovana Fernanda Cosi Bento, Mariana de Castro Silva, and Márcia Guimarães da Silva
47 The role of innate immunity in neuro-immune dysfunction
Isaac R Melamed and Caley Buckley
48 Platelet-derived serotonin drives age-dependent severe COVID-19
Davide Marotta, Chiara Perrucchini, Marta Grillo, Micol Rava, Valeria Fumagalli, Leonardo Giustini, Violette Mouro, Donato Inverso, Luca Guidotti, Matteo Iannacone, and Marco De Giovanni
49 Investigating how Mycobacterium tuberculosis promotes its survival in neutrophils.
Ananda N Rankin, Asya Smirnov, and Christina L Stallings
50 molecular mechanisms of long-term memory in conventional dendritic cells (cDC) progenitors
Sahar S.H Tehrani, Miguel Patrício, Vasco Correia, and Carlos M. Minutti
51 Systems Approaches in Co-Infections
Philipp DK Walch
52 Characterization of myeloid cells in circulation and synovial fluid of patients with psoriatic arthritis
Katerina Oikonomopoulou1, Noah Fine1, Michael Glogauer2,3, and Vinod Chandran1,4,5,6,7
53 Spinal cord injury causes immune dysfunction during systemic infection
Julie R Zielonka1, Colleen E Tordoff1, Gracie F Anker1, Lauren A Coulson1, Emily A Swarts1, Elahe Alizadeh2, and Faith H Brennan1
54 HMGB1 mediates G-Quadruplex-induced Innate Immunity activation
Alessio De Magis and Marco Bianchi
55 Drosophila: A Rising Model for the Study of Adipose Tissue Macrophages
Adam Bajgar and Gabriela Krejčová
56 Harnessing Drosophila as a model for immunometabolic regulation
Gabriela Krejčová
57 Intolerant Response (Trained Immunity) of Macrophages in Patients with Non-Infectious Diseases
Alexander N. Orekhov1, Natalia V. Elizova 1, Anastasia V. Poznyak 2, and Vasily N. Sukhorukov 1
58 The Role of Macrophage Intolerant Response (trained immunity) in Chronic Obstructive Pulmonary Disease: Cytokine Dynamics and Inflammatory Mechanisms
Alexey V. Churov1,, Sukhorukov N. Vasiliy3, Natalia V. Elizova1, and Alexander N. Orekhov1
59 Role of Defective Interfering Genomes in Complement-mediated Lysis of Parainfluenza Virus Infected Cells
Jenna R. Aquino, Griffith D. Parks, and Candace R. Fox
60 Epigenetic Regulation of Non-tolerant Immune Response: Focus on IL1β
Vasily N Sukhorukov1, Daria Dmitrievna Borodko1, Andrey Vladimirovich Omelchenko1, Anastasia Vladimirovna Poznyak2, and Alexander Nikolaevich Orekhov1
61 Neutrophil-derived Semaphorin 4A promotes inflammation resilence of myeloid-biased hematopoietic stem cells
Lev Silberstein1, Sanika Gupte1, Dorsa Toghani1, Thomas Worzfeld3, Isabel Beerman, Bongsoo Park, and Atsushi Kumanogoh 4
62 Modeling adipose tissue dysfunction in polycystic ovary syndrome in vitro using 2D and 3D cell culture systems
Anja Dekanski1, Congru Li1, Lena Emilia Schobloch1, Eva Lindgren1, Shane Wright1, Angelica Linden Hirschberg2, Duarte Ferreira1, Volker Lauschke1, Nayere Taebnia1, and Elisabet Stener-Victorin1
63 Gadd45β Regulates Type I Interferon Signaling by Promoting G3BP-Mediated Stress Granule Formation
Jong-Soo Lee
64 The E3 ubiquitin ligase MARCH2 controls inflammation by autoubiquitination
Jong-Soo Lee
65 MARCH5 promotes NLRP3-NEK7 Complex Formation via ubiquitination of NLRP3
Jong-Soo Lee
66 Negative Feedback Between TBK1 and NQO1 Fine-Tunes Antiviral Defense Mechanisms
Jong-Soo Lee
67 The novel immunobiotic Clostridium butyricum S-45-5 displays broad-spectrum antiviral activity in vitro and in vivo
Jong-Soo Lee
68 SIAH1-Mediated Degradation of USP19 Enhances Antiviral Type I IFN Signaling
Jong-Soo Lee
69 Chemokines in the initiation of autoinflammation in the mouse model of chronic multifocal osteomyelitis
Pranav Gulati, Nataliia Pavliuchenko, and Tomas Brdicka
70 Unravelling the ultrastructure of neutrophil extracellular traps (NETs)
Kateřina Paldusová1, José Alfredo González Navarro1, Marek Cebecauer1, and Jan Tkadlec2
71 CXCL12 enhances CXCR4-mediated antitumor immune responses in a syngeneic mouse model of malignant mesothelioma
Francesca Caprioglio1, Andrea Lamarca1, Liam S. Colley2, Annamaria Molinario2, Angela A. Rilievo1, Massimo P. Crippa2, Rosanna Mezzapelle1,2, and Marco E. Bianchi1,2
72 Expression analysis and functional characterization of CD25 on conventional dendritic cell in liver cancer
Aurora Gazzillo2,, Camilla Volponi2,, Christian Simini2,, Adriana Romanzi2,, and Eduardo Bonavita2,
73 The alarmin HMGB1 induces cytokine release in myeloid cells via both TLR4 and RAGE, by separate functional domains and kinetics
Xingzhao Wen2, Bram van Gaans1, Rebecka Heinbäck2, Richard Davies1, and Helena Erlandsson Harris1
74 LPS-Induced Immune Exhaustion Alters Myeloid Function and Exacerbates Aging-Related Diseases
Guillaume Blot, Frédérick Fournier, Vera Guber, Jeffrey Sullyvan, Masayuki Hata, Ariel Wilson, and Przemyslaw (Mike) Sapieha
75 Genetic Variations in Inflammatory Pathway Genes and Their Implications for Longevity
Alexey Churov, Mikhail Arbatskiy, and Dmitriy Balandin
76 Unraveling Macrophage Senescence: A Novel In Vitro Model Reveals New Insights into Transcriptomic and Epigenetic Signatures and Cytokine Responsiveness
Djurdja Pasajlic1, Maud Plaschka3, Frank Assen1, Anna Kusienicka1, Peter Traxler1, Lisa Ellen Shaw1, Ulrike Mann1, Mathias Mueller4, Thomas Decker2, Wolfgang Weninger1, Florian Halbritter3, and Matthias Farlik1
77 Mitochondrial DNA efflux via mitochondrial herniation induces the inflammatory senescence associated secretory phenotype in senescent vascular endothelial cells
Yusuke Ichiyama1, Agnieszka Dejda, Vera Guber, Roberto Diaz-Marin1, Jeffrey Sullivan1, Guillaume Blot1, Frédérik Fournier1, Gabrielle Girouard1, Ariel Molly Wilson, and Przemyslaw Sapieha1,
78 TLR4 activation impacts the HMGB1 interactome in monocytes
Rebecka Heinbäck1, Marit van der Zijde1, Choi Har Tsang1, Alexander Espinosa1, Cecilia Aulin1, and Helena Erlandsson Harris1,2
79 Nasal Protollin promotes increased clearance of brain amyloid beta by modulation of peripheral monocytes in APP/PS1 mice
Panayota Kolypetri1, Patrick Da Silva1, Somen K Mistri1, Rachael R Cecere1, Estefania Solana Leon1, Nikolaos Kalavros2, Athanasios Ploumakis2, Ioannis S Vlachos2, Ting Yang1, Lei Liu1, Silke Nuber1, Andrew M Stern1, Nikoleta Delivanoglou1, Rajesh K Krishnan1, Murugaiyan Gopal 1, Dennis J Selkoe1, and Howard L Weiner1
80 Bergeyella cardium variant induces a unique cytoplasmic vacuolization cell death via SLC9A9-mediated vacuole fusion
Rudi Mao and Xiaopeng Qi
81 Use of the RNA Technology for the therapy of infectious diseases based on humoral innate immunity molecules
Virginia Cianchi1,2, Matteo Stravalaci 1,3, Isabel Pagani4, Elisa Vicenzi4, Alberto Mantovani1,2,5, Elena Magrini1,2, and Cecilia Garlanda1,2
82 Exploit Neutrophil Heterogeneity to Induce Synthetic Lethality in Breast Cancer
Matteo Massara, Cindy Garda, Letizia Boffa, and Arianna Calcinotto
83 ARCO is an IFN-restricted immunometabolic decoy LPS receptor
Fiachra Humphries
84 Secretory Leukocyte Protease Inhibitor (SLPI) as a regulator of macrophage-mediated immune responses
Mariia Tyshchenko1,3, Natalia Pocałuń1,3, Kamila Kwiecień1, Patrycja Kwiecińska1, Anna Grochot-Przęczek2, Joanna Cichy1, Mieszko Wilk1, and Ewa Oleszycka1
85 SLPI Protein as a Potential Regulator of Neutrophil Maturation and Migration
Ivan Sinkevich1, Joanna Cichy1, Patrycja Kwiecinska2, Joanna Skrzeczynska-Moncznik1, Pawel Majewski1, Monika Majchrzak-Gorecka1, Michal Santocki3, and Elzbieta Kolaczkowska3
86 Application of blood derived mast cells stimulation for detection allergic conditions
Alicja Dziadowiec1,2, Mateusz Kwitniewski2, Patrycja Kwiecinska3, Ana Koren4, Peter Kopac4,5, Oskar Solarski6, Marta Kolacinska-Flont7, and Grzegorz Porebski1
87 Deciphering the contribution of IL-1 in lung homeostasis and disease: focus on the crosstalk between alveolar macrophages and epithelial cells
Rute Daniela Matos Gonçalves, Diogo Silvério, Clara Bento, Marcos Cardoso, and Margarida Saraiva
88 Conventional Dendritic Cells in Cancer: Functions and Therapeutic Potential
Eduardo Bonavita
89 Cortisol-resistant Chimeric Antigen Receptor (CAR)-NK cells overcome steroid-induced immunosuppression in lung cancer
Soura Chakraborty, Christopher Ward, Jhuma Pramanik, Sanu K. Shaji, Yumi Yamashita-Kanemaru, Rahul Roychoudhuri, Hosni Hussein, and Bidesh Mahata
90 β-Glucan Prophylactic Treatment Enhances Antiviral Immunity and Reduces Immune Suppression During Chronic Infection
Wei Liu1,2, Zhe Lu3, Olivia Stencel3, Eleni Vasileiou3, Ann-Sophie Mai1, Stefan Janssen4, Arndt Borkhardt3, and Aleksandra Pandyra1,2,3
91 The CREB Binding Protein (CBP) as Regulator of the Immune Response in Myeloid Cells
Ann-Sophie Mai1,2,3, Diana Novak1,2, Olivia Stencel4, Pawel Stachura4, Julian Schliehe-Diecks4, Ammarah Anwar4, Sanil Bhatia4, Arndt Borkhardt4, and Aleksandra A. Pandyra1,2,3,4
92 Manipulating functional pleiotropy of macrophage through dynamic control of SRC family kinases (SFKs)
Cristina Torres-Torres1, Paul Rivier1, Lucia Campos-Perello1, Christiane Oddou1, Fabrice Senger1, Ingrid Bourrin1, Alexei Grichine1, Mylène Pezet1, Satish Moparthi3, Stéphane Vassilopoulos3, Benjamin Graedel2, Lucien Hinderling2, Olivier Pertz2, Jordan Allard1, Chantal Thibert1, Eva Faurobert1, Emmanuelle Planus1, and Olivier Destaing1
93 Serum levels of TGF-β and calprotectin decrease during successful therapy with IL-17 inhibitors
Stepan Coufal1, Zuzana Reiss1, Michaela Novakova2, Jan Hugo3, Tomas Thon1, Miloslav Kverka1, Helena Tlaskalova-Hogenova1, Petr Bohac2, Zuzana Jiraskova Zakostelska1, and Filip Rob2
94 Podosomes in T lymphocytes: revisiting their structure and function
Lucía Campos Perelló, Cristina Torres Torres, Christiane Oddou, Ingrid Bourrin-Reynard, Alexei Grichine, Mylène Pezet, Emmanuelle Planus, Eva Faurobert, and Olivier Destaing
95 Rewiring of lipid metabolism upon sensing of fungal melanin is an essential host defense mechanism in alveolar macrophages
Vassilis Nidris1,2, Ioannis Morianos1,2, Evangelia Inze1, Eva Papadogiorgaki3, and Georgios Chamilos1,2
96 Albumin orchestrates a natural host defense mechanism against mucormycosis
Ioannis Morianos1,2, Antonis Pikoulas2, Vassilis Nidris1,2, Rania Hamdy3, Ángeles López-López4, Maria Moran-Garrido4, Valliappan Muthu5, Maria Halabalaki6, Maria Papadovasilaki1, Irene Kyrmizi1, Yiyou Gu7, Robina Aerts8, Toine Mercier8, Yuri Vanbiervliet8, Sung-Yeon Cho9, Amy Spallone9, Dimitrios Samonakis2, Efstathios Kastritis10, Elias Drakos2, Maria Tzardi2, Aristides Eliopoulos10, Konstantina Georgila10, Agostinho Carvalho11, Oliver Kurzai12, Shivaprakash M Rudramurthy13, Fanny Lanternier14, Kyriakos Petratos1, Johan Maertens8, Vincent M Bruno15, Dimitrios P Kontoyiannis9, Coral Barbas4, Sameh S.M. Soliman3, Ashraf S Ibrahim7, and Georgios Chamilos1,2
97 Macrophages as regulators of thymic size via TLR4-TRIF-p65 driven priming of efferocytosis
Andri L Lemarquis, Daniel Ghazarian, and Marcel van den BRink
98 The Role of ER Stress-Related Genes IRE1a and PERK in Regulating Inflammatory Cytokine Expression in Macrophages
Mariam Bageri Ekta1 and Vasily Sukhorukov
99 Delineating the therapeutic potential of trained neutrophils in the context of cancer therapy
Despoina, Xanthopoulou, Lydia Kalafati, and Triantafyllos Chavakis
100 Analysis of megakaryopoiesis in metabolic dysfunction-associated steatotic liver disease (MASLD)
Shu Yan1, Lydia Kalafati1, Kyoung-Jin Chung1, Gundappa Saha2, George Hajishengallis2, and Triantafyllos Chavakis1