11th International Conference on Autoimmunity: Mechanisms and Novel Treatments

Posters

Important: The program online is copyrighted to each author and should not be copied and pasted!
43 Selective ROCK2 inhibitor ameliorates established dermal and pulmonary fibrosis in murine systemic sclerosis by shifting the balance between Th17 and Treg cells
Wei Chen1, Melanie Nyuydzefe1, Julien Moretti1, Elizabeth Stillman2, Linh Nguyen2, Christophe Pichavant2, Malavika Ghosh2, Samuel D Waksal1, and Alexandra Zanin-Zhorov1
44 Inhibition of Bruton´s tyrosine kinase in Th17-adoptive transfer EAE
Rosa Schmitz, Clara de la Rosa, and Anneli Peters
45 The interplay between CD4 T cells and fibroblasts in salivary glands drives autoimmune pathology in Sjogren's syndrome
Kunihiro Otsuka, Hiroyuki Kondo, Shin-Ichi Tsukumo, and Koji Yasutomo
46 Novel tissue targeted immunomodulating molecule to treat Type 1 Diabetes
Luis F Godinho1, Adam P Curnock1, Matthew W Becker2, Todd M Brusko3, Edward A Phelps2, David X Overton1, Veronica Gonzalez1, Tara M Mahon1, Giovanna Bossi1, Hussein Al-Mossawi1, Mollie K Huber3, and Andrece Powell2
47 Role of A20 Deficiency in Autoimmunity and B Cell Lymphomagenesis
Seren Baygün and Marc Schmidt-Supprian
48 Enhanced Osteoclast Activity through NRF2 Pathway Activation
Sandra Y Fukada1, Cesar A Speck1, Thiago M Cunha2, and Fernando Q Cunha2
49 AN EX-VIVO MODEL FOR PRECLINICAL RESEARCH IN OSTEOARTHRITIS: PATIENT-DERIVED EXPLANTS OF HUMAN SYNOVIUM
Claudia D’Oria1,2, Gilberto Cincinelli2,3, Ramona Bason1, Federica Pisati5, Francesca Simoncello1, Isabella Scotti2, Laura Giudice2,3, Ilaria Suardi2,3, Paolo Ferrua6,7, Chiara Fossati6, Pietro Simone Randelli6,7, Roberto Caporali2,3, Massimiliano Pagani1, and Francesca Ingegnoli2,3
50 Development of a safe, cost-effective, IL15 armored CD19-BCMA- Bi-Chimeric Antigen Receptor (Bi-CAR) modified Allogeneic iNK Platform for the Treatment of Lupus Patients
Sourindra Maiti1, Andrea Chambers4, Vishal Khairnar2, Liang Lin1, Solgalim Diaz2, David Zou3, Wei Li5, and Hao-Ming Chang1
51 TRPM7-kinase promotes pathogenic Th17 responses during CNS autoimmunity
Katharina Jacob2,3, Anna S Thomann1, Neysa Rodriguez Murillo1, Franz Bauernschmitt1, Lisa Ann Gerdes1, Christian Weber3, Thomas Gudermann2, Anneli Peters1, and Susanna Zierler2,4
52 Chromatin organizers SATB1 and BACH1 regulate (auto)immunity
Dionysios A Papamatheakis1,2, Eleftherios Morres1,2, Petros Tzerpos3, Tomas Zelenka4, Despina Tsoukatou2, Manuela Kapsetaki2, and Charalampos G Spilianakis1,2
53 Novel, Selective BRD4(BD2) Inhibitor DC-9476 demonstrates a potent anti-inflammatory mechanism
Michal Segal Salto, Steven Ferrara, Kelvin Chan, Elvira Haimov, Georg Duenstl, and Luca Rastelli
54 Deciphering the role of DNA damage in T-helper lymphocytes in autoimmunity and T-cell responses
Ermioni S Arvanitaki1,2, George Niotis1,2, Alexia Akalestou-Chlocher1,2, Robert Lorenz Chua3, Christian Conrad3, and George A Garinis1,2
55 DNA damage-dependent autophagy in macrophages promotes the MHC-II presentation of immunogenic peptides
George Niotis1,2, Ermioni S. Arvanitaki1,2, Emmanouil Theodorakis1,2, Adrian Schmalen3, and George A. Garinis1,2
56 Heme oxygenase-1 signaling in the blood-brain barrier in chronic stress
Ilaria Palagi , Eva Schramm , and Ari Waisman
57 The role of interferon-gamma signaling in NG2-glia cells during CNS inflammation
Dana Toktarkhanova
58 Aging-associated microbiota compromises Regulatory T cell function by triggering DNA damage and cellular senescence
Jefferson A Leite, Natalia Notarberardino Bos, Emmanouil Stylianakis, Rebecca Jasser, Zeynep Ergun, Katlynn Carter, Aysan Pousardegh Zonouzi, Xinyuan Liu, Nadine Hoevelmeyer, Christoph Reinhardt, and Ari Waisman
59 Oral Microbiome Disrupts Epithelial Integrity and Promotes Inflammation in Sjögren's Syndrome Organoids
Ye Jin Jeong
60 Dynamics of circulating MOG-reactive B cells in children
Stephan Winklmeier1, Kathrin Schanda2, Georgia Koukou3, Aikaterini Karydi3, Heike Rübsamen1, Jan Bartosch1, Eva-Maria Wendel4, Markus Reindl2, Kevin Rostásy3, Edgar Meinl1, and Simone Mader1
61 Treg cells as modulators of gluten-induced inflammation in celiac disease
Janet Godoy1, Aline Pesi2, Detlef Schuppan2,3, and Luciana Berod1