2nd International Conference on Mesenchymal Cells in Health & Disease

Posters

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51 HAPLN1: a bone marrow homing and drug resistance factor linked to poor outcomes in patients with multiple myeloma
Hae Yeun Chang and Shigeki Miyamoto
52 Fibroblasts response to oligo(ethylene glycol) methyl ether methacrylate (OEGMA)-based hydrogel dressing material for the treatment of infected chronic wounds
Agata Przekora1, Marta Trzaskowska1, Ann-Kathrin Kissmann2, Ahmet Cetinkaya3, Frank Rosenau2, and Joanna Pietrasik3
53 Chitosan/curdlan hydrogel film as a potential carrier of fibroblasts in a cell-based therapy of chronic wounds
Aleksandra Maciejczyk, Paulina Kazimierczak, Michal Wojcik, Vladyslav Vivcharenko, and Agata Przekora
54 In vitro modeling of the colonic mucosa for identification of novel therapeutic targets for the treatment of inflammatory bowel disease
Sage E Foley1, Sarah S Wilson2, Yunhao Tan1, Sudiksha Chaulagain1, Nicole A Chionchio2, Jamie E Erickson2, Christina L Gomez2, Lori Patnaude2, Abhinav Sharma3, Emily Sylvain2, Monica Viladomiu1, Xiaoming Wu2, Timothy Radstake4, Robert M Townsend1, Elisabeth E Fiebiger1, Matthew M Staron2, and Amlan Biswas1
55 Effectiveness of the production of bioengineered stem cell-based bone graft for osteoporotic fracture treatment – a comparative study using perfusion and rotating bioreactor systems
Paulina Kazimierczak1, Grzegorz Kalisz2, Michał Wójcik1, Anna Sroka-Bartnicka2, and Agata Przekora1
56 the use of autologous adipose tissue-derived mesenchymal stem cells in the treatment of chronic posttraumatic spinal cord injury in a domestic ferret patient – a case report
Alicja Wójcik2, Agata Przekora2, and Łukasz Juszkiewicz1
57 Mesenchymal stem cells as a potential source of cells for the generation of tissue-engineered cartilage
Vladyslav Vivcharenko1, Krzysztof Palka2, and Agata Przekora1
58 Fibroblast response to silver nanoparticles-loaded wound dressing with antimicrobial properties
Michał dr Wójcik and Agata prof Przekora
59 Investigating GAS6-AXL signalling, a potential novel pathway regulating homeostatic and tumorigenic intestinal fibroblasts
Emma W Viitala
60 HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling
Michela Terri 1,3, Pilar Sandoval2, Giulio Bontempi1,3, Claudia Montaldo1, Henar Tomero-Sanz2, Flavia Trionfetti1,3, Lucía Pascual-Antón2, Irene Clares-Pedrero2,4, Cecilia Battistelli3, Sergio Valente5, Clemens Zwergel5, Antonello Mai5, Laura Rosanò6, Miguel Ángel Del Pozo7, Miguel Sánchez-Álvarez7, Carlos Cabañas2,4, Marco Tripodi3, Manuel López-Cabrera2, and Raffaele Strippoli3
61 HDAC1/3 inhibition blocks Poly(I:C)-induced Type I Interferon response and modulates the mesenchymal/inflammatory phenotype in mesothelial cells
Flavia Trionfetti1, Claudia Montaldo1, Ivan Caiello3, Giulio Bontempi1,2, Michela Terri1,2, Marta Tiberi1, Vanessa Marchant4,5, Alessandro Domenici6, Paolo Menè6, Marco Cordani7, Clemens Zwergel8, Giusi Prencipe3, Marta Ruiz-Ortega4,5, Sergio Valente8, Antonello Mai8, Marco Tripodi2, and Raffaele Strippoli1,2
62 Lymph node homeostasis is driven by lymphocytes number and maintained robust tissue topology
Spyridon Makris1, Hugh Ford1, Charlotte M. de Winde2, Daniel Schewing1, Agnesska C. Benjamin1, Simone Dertschig3, Victor G. Martinez4, and Sophie E. Acton1
63 Mechanism of fibroblast differentiation within lymph node T cell zones.
Nagham Alouche1, Hélène Cannelle1, Stéphanie Favre1, Maeva Delacretaz1, Chloé Chapuis1, Tom Cupedo2, Christian W Siebel4, Burkhard Ludewig3, Freddy Radtke5, and Sanjiv Luther1
64 Characterization of a new fibroblast subset in lymph node medullas and its role in innate and adaptive immunity
Marija Jokic, François Renevey, Hélène Cannelle, Nagham Alouche, and Sanjiv Luther
65 Delineation of fibroblast-like synoviocyte-mediated immune responses in the pathogenesis of rheumatoid arthritis
Elpida Neofotistou-Themeli1,2, Panagiota Goutakoli1,2, Theodoros Chanis3,4, Maria Semitekolou5,6, Eirini Sevdali1,2, George Bertsias1,2,7, Panos Verginis2,8, and Prodromos Sidiropoulos1,2,7
66 Osteoblasts and macrophages response to nanocomposite biomaterials for bone regeneration applications
Marta Trzaskowska1, Vladyslav Vivcharenko1, Wojciech Franus2, and Agata Przekora1
67 Common progenitor of fibroblastic reticular cells and vascular smooth muscle cells in murine lymph nodes
Lisa Kurz, Mechthild Lütge, Hung-Wei Cheng, Lucas Onder, and Burkhard Ludewig
68 Circulating cells with mesenchymal phenotype are increased in patients with rheumatoid and psoriatic arthritis
Maria Kyriakidi1,2, Eleni-Kyriaki Vetsika1,2, George E Fragoulis2, Maria Sakkou1, Nikolaos I Vlachogiannis2, Maria Tektonidou2, George Kollias1, and Petros P Sfikakis1,2
69 PI16+ reticular cells form reactive macrophage niches in human lymph nodes
Lisa Kurz1, Mechthild Lütge1, Yves Stanossek1,2, Samuel Meili1,2, Hung-Wei Cheng1, Angelina De Martin1, Joshua Brandstadter3, Ivan Maillard3, Sandro Stoeckli2, Natalia Pikor1, Lucas Onder1, and Burkhard Ludewig1
70 The role of splenic stromal cells in the innate immune defense against infection
Andrzej Gruza1, Hrönn Kjartansdottir1, Claus Vogl1, Thomas Filip1, Caroline Lassnig1,2, Katarzyna M. Sitnik1, Mathias Müller1, and Birgit Strobl1
71 Tissue resident mesenchymal cells: friend or foe in chronic graft-versus-host disease after hematopoietic stem cell transplantation
Pedro Vallecillo García, Katarina Riesner, Lydia Verlaat, and Olaf Penack
72 Protective role of an extracellular matrix-hydrogel on healing tissues reduces post-operative adhesion formation
Pilar Sandoval1, Henar Tomero-Sanz1, Lucía Pascual-Antón1, Michela Terri2,3, Raffaele Strippoli2,3, Miguel Ángel del Pozo3, Timothy J Keane4,5, Molly M Stevens4, and Manuel López-Cabrera1
73 Mesothelial-to-mesenchymal transition as a therapeutic target by using antibody-drug conjugates
Henar Tomero-Sanz1, Pilar Sandoval1, Lucía Pascual-Antón1, Myriam Fabre2, and Manuel López-Cabrera1
74 Diverse fibroblast reprogramming in intestinal regeneration and cancer
Athanasia Stavropoulou1,2, Christina Paraskeva1, Niki Chalkidi1, Christoforos Nikolaou2, and Vasiliki Koliaraki1
75 The role of Notch3 in intestinal carcinogenesis
Niki Chalkidi1, Athanasia Stavropoulou1,2, Maria Sakkou2, Christoforos Nikolaou2, and Vasiliki Koliaraki1
76 Fibroblast activation and functions in intestinal regeneration
Christina Paraskeva1, Athanasia Stavropoulou1,2, Martina Samiotaki2, Christoforos Nikolaou2, and Vasiliki Koliaraki1
77 Lymph node stromal cells prime tissue environment and lead to reduced organ filtering function after vaccination
Ruth Fair-Mäkelä, Pinja Thorén, Joni Laakkonen, Pia Sundqvist, Laura Kähäri, Jonna Alanko, and Marko Salmi
78 age-associated changes in the mouse intestinal stroma
Vasiliki Zoi Arvaniti1, Maria Jose Rodriguez Sanchez3,, Athanasia Stavropoulou1,2, Martina Samiotaki2, Christoforos Nikolaou2, and Vasiliki Koliaraki1
79 Unraveling Harmony: disrupted Bone Marrow Stromal Niche in Clonal Hematopoiesis and Myelodysplasia
Karin D Prummel1, Kevin Woods2, Max Kholmatov1, Gereon Poschmann3, Kai Stühler3, Rebekka Wehner4, Marc Schmitz4, Uwe Platzbecker5, Judith B Zaugg1, and Borhane Guezguez2
80 A macrophage-myofibroblast cell circuit reveals cold fibrosis following myocardial infarction
Shoval Miyara
81 Inflammatory mediators exacerbate intestinal fibrosis enhancing epithelial-mesenchymal transition through the activation of S1PR3 signaling
Giulia Rizzo1, Giada Mori1, Samuel Elias Pineda Chavez2, Marek Wozny2, Alejandra Carriles Linares2, Laura Loy3, Cristina Bezzio3, Paola Spaggiari4, Arianna Dal Buono3, Roberto Gabbiadini3, Michele Carvello5, Antonino Spinelli2,5, Alessandro Repici2,6, Alessandro Armuzzi2,3, Stefania Vetrano1,2, and Cristina Mascaraque7
82 Influence of caveolin-1-dependent stromal remodeling on tumor immune infiltration
Alba Martín-Martín1, Mauro Català-Montoro1, Miguel Sánchez-Álvarez1,2, Alice Perucca3, Stefanie Wculek4,6, Inmaculada Navarro-Lérida5, Mónica Toledano-Donado1, David Sancho6, Xavier Trepat3, and Miguel A Del Pozo1
83 Lipids drive myofibroblast activation and the epithelial-mesenchymal transition process in Crohn's Disease.
Giulia Rizzo1, Marek Wozny2, Giada Mori1, Faris Hrvat2, Samuel Elias Pineda Chavez2, Alejandra Carriles Linares2, Lavinia Morosi10,11, Giuseppe Martano11,12, Serena Maria Luisa Ghisletti3, Francesco Gandolfi3, Veronica Vallelonga3, Marianna Paulis4, Laura Loy6, Cristina Bezzio6, Paola Spaggiari7, Arianna Dal Buono6, Roberto Gabbiadini6, Michele Carvello8, Antonino Spinelli2,8, Alessandro Repici2,9, Alessandro Armuzzi2,6, and Stefania Vetrano1,2
84 Cellular complexity in murine ileitis: Different fibroblasts propel spatially defined inflammation in the ileum through TNFR1 signalling
Lida Iliopoulou1, Christos Tzaferis1, Alejandro Prados, Fani Roumelioti1, Maria Aslani1, Konstantinos Ntatsoulis1, Konstantinos Apostolou-Karampelis1, Vasiliki Koliaraki3, and George Kollias1
85 Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic development
JiHyun Sim
86 Mesenchymal stromal cell role in muscle regeneration and disease
Valentina Taglietti, Andreea Cojocaru, Laurent Tiret, and Frederic Relaix
87 Unraveling Stromal-Endothelial Crosstalk: Inflammation-modulated shaping and Extracellular Vesicle dynamics
Cristina Liboni2, Alessandra M Testa1, Diana Corallo2, Ricardo Sanchez-Rodriguez1, Antonella Viola1, and Roberta Angioni1,2
88 complementary deletion and overexpression screens identified novel regulators of primary synovial fibroblasts’ activation programs
Suppawat Kongthong1,2, Angela Zou1,2, Gerald Watts1, Cassandra Murphy1, Alisa Mueller 1, Michael Brenner1,2, Matthew Chamberlain1, and Jacqueline Perrigoue1
89 Tumors induce chimeric myeloid-fibroblast states with functional roles in adaptive immunity.
Evangelia Chavdoula1, Dimitrios Koumadorakis1, Maria-Michaela Alvanou1, Konstantinos Ioannidis1, Eirini Deligianni1, Grigorios Barnasas1, Emmanouil Aerakis1,2, Alexia-Christina Vakouftsi3, Kostantinos Vachlas3, Charalambos Zisis3, Ioannis Vamvakaris4, and Maria Tsoumakidou1,2
90 A novel activated cancer-associated pericyte (actCAP) state is linked to lung tumor innervation.
Eleni Liapi1, Raphaela S Milona1, Alexia-Christina Vakouftsi3, Kostantinos Vachlas3, Charalambos Zisis3, Ioannis Vamvakaris4, and Maria Tsoumakidou1
91 De-activating the inflammatory and fibrotic potential of fibroblasts by newly synthesized small molecule inhibitors
Filippos Charalampous1, Dimitris Brisimis1,2, Dimitra Papadopoulou1, Vasiliki Mavrikaki1,3, Alexios Matralis1, and George Kollias1,2,4
92 Dissection of Beta-Herpesvirus Interactions with Mesenchymal Cells Identifies STAT1 as a Driver of Herpesvirus Latent Persistence
Katarzyna Sitnik3, Fran Krstanovic2, Natascha Goedecke1, Ulfert Rand1, Tobias Kubsch1, Henrike Maass1, Yeonsu Kim1, Ilija Brizic2, and Luka Cicin-Sain1
93 Cellular interactions underlying the plasticity of intestinal stem cell niche
Bahar Degirmenci Uzun, İlke Sari, and Beliz Uzun