6th International Conference on Cytokines in Cancer

Posters

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63 Activation of interferon-signaling in chronic lymphocytic leukemia cells by the NFkB inhibitor anakinra
Tina YuXuan Luo1, BoYang Su3, Vincent Hung2, YuHan Luo1, Yonghong Shi2, Guizhi Wang2, and David E Spaner5
64 eEF2 Kinase signaling drives pancreatic tumor growth and induces protumorigenic tumor microenvironment: A Novel Molecular Target
Didem Karakas
65 Ring Finger Protein 169 binds to the SOCS2-SH2 exosite to allosterically enhance SH2 binding to phosphorylated ligands
Kunlun Li, Yuntong Wu, Ruth Cuzzupe, Laura Dagley, Colin Hockings, Grace Bidgood, Andrew Wei, Rhiannon Morris, Cyrus Tan, Farhad Dehkhoda, Narelle Keating, Edmond M Linossi, Brad Sleebs, Jeffery J Babon, Nadia J Kershaw, and Sandra E Nicholson
66 Proapoptotic activity of ursolic derivatives in MDA-MB-231 breast cancer cells.
Krzysztof Bielawski1, Agnieszka Gornowicz2, Wojciech Szymanowski2, Olga Michalak3, Piotr Krzeczynski3, and Anna Bielawska2
67 Anti-proliferative effect of novel compounds based on thiopyrano[2,3-d]thiazoles in colorectal DLD-1 carcinoma cells
Roman Lesyk1, Yuliia Kozak2, Nataliya Finiuk2, Olha Klyuchivska2, Krzysztof Bielawski3, and Anna Bielawska4
68 The influence of novel ursolic acid derivatives on IL-6 and TNF-α concentrations in MDA-MB-231 breast cancer cells.
Anna Bielawska1, Agnieszka Gornowicz1, Olga Michalak2, Marcin Cybulski2, and Krzysztof Bielawski3
69 K29-linked ubiquitination of IRF9 regulates the strength of type-I interferon signaling
Tengfei Ren2, Wei He2, Qian Zhao2, Zhijing Zheng2, Yibo Zuo1, Yukang Yuan1, and Hui Zheng1
70 Medullary sinus macrophages limit cancer therapy efficacy by an efferocytosis-induced IL-33/ST2 axis in the tumor-draining lymph node.
Sara Lamorte, Robbie Jin, Kitty Liu, Rene Quevedo, Luke Neufeld, Tracy McGaha, and Teresa Ciudad
71 Modulating the immunosuppressive pancreas tumor microenvironment through intratumoral delivery of cytokine-encoding mRNAs
Chaitanya Naimesh Parikh1, Kelly De Marco1, Youwei Qiao1,2, Griffin Kane3, Loretah Chibaya1, Lin Zhou1, Katherine Murphy1, Li Li2, Prabhani Atukorale3, Wen Xue2, and Marcus Ruscetti1
72 Use of long-acting c-type natriuretic peptide for solid tumor therapies
Zhen Lu1, Ioannis Verginadis2, Motofumi Kumazoe3, Gerardo M Castillo4, Yao Yao4, Sandra Bicher2, Menghao You1, Takashi Nojiri5, Yasutake Tanaka3, Yoshinori Fujimura3, Hiroaki Onda3, Yui Hatakeyama3, Akiko Nishimoto-Ashfield4, Katrina Bykova4, Nikolay Buynov4, Hirofumi Tachibana1, Constantinos Koumenis2, Elijah Bolotin4, Serge Fuchs1, and Rebecca E Guerra4
73 TGF-β1 induces metastatic colonization to skeletal muscle in mouse models of metastatic breast cancer
Alastair A.E Saunders1, Rachel E Thomson1, Kellie E Mouchemore2, Chris Karagiannis1, Lauren S James1, David Freestone4, Thomas B Chadwick1, Wayne Du1, Craig A Goodman1, Adam Hagg1, Hongwei Qian1, Allan D Burrows2, Thomas Gebhardt4, Robin L Anderson2, and Paul Gregorevic1
74 Selective ASO-based JAK2 inhibitor for the treatment of myeloproliferative disorders
Sandra Paulina Smieszek and Bartlomiej Przychodzen
75 PP2C family phosphatases regulate multiple cell death pathways induced by TNF signaling.
Bogdanova Daria A1,3, Lagorgette Lisa -2, Demidov Oleg N1,2,3, and Appella Ettore -4
76 Immune-derived inflammation in a microbiota-dependent model of immune checkpoint inhibitor colitis
Sarah M Schneider1,4, Yifan Zhou1, Elizabeth M Park1,2, Laura M Kahn1,4, Morgan N Riba1,3,4, Bhakti Patel1, Josue E Pineda1,4, Meredith Klay1, Wanying Na1, and Stephanie S Watowich1,4
77 Limiting Macrophage Pro-Tumor Response in cancer by Targeting CTSB and non-Apoptotic Caspase-8
Emeline Kerreneur, Paul Chaintreuil, sonia Boulakirba, Guillaume Robert, Patrick Auberger, and Arnaud Jacquel
78 Effect of acute myeloid leukemia (AML) and cytarabine on the presence/intensity of inflammatory and anti-inflammatory cytokines in mouse testicular cells; possible regulation by granulocyte colony-stimulating factor.
Mahmoud Huleihel1, Bara'ah Khaleel1, Tamar Eliahu1, Eden Arazi1, and Eitan Lunenfeld2
79 Potentiating CAR T cell therapy through synthetic IL-9R signaling
Sofia Castelli, Ugur Uslu, Amanda Finck, Mikko Siurala, Regina M Young, and Carl H June
80 Targeting CAIX in pancreatic cancer leads to changes in cytokine production, enhancing anti-tumor immune response
Lucia Škvarková1, Sabína Strapcová1, Mária Bartošová1, Ingeborg Režuchová1, Lucia Csáderová1,3, Olga Sedláková1, Ľubomíra Lukáčiková1, Magdaléna Barátová1, Miriam Zaťovičová1,2, Jaromír Pastorek2, and Eliška Švastová1,3