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A chromatin-regulated biphasic circuit coordinates inflammation and trained immunity
Musa M Mhlanga
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46 |
A cytokine/PTX3 prognostic index as a predictor of mortality in sepsisSadaf Davoudian1, Daniele Piovani2, Antonio Desai2,3, Sarah N Mapelli1, Roberto Leone1, Marina Sironi1, Sonia Valentino1, Rita Silva-Gomesana1, Matteo Stravalaci1, Carlo Fedeli3, Denise Comina3, Stefanos Bonovas2, Antonio Voza2,3, Alberto Mantovani1,2,4, and Barbara Bottazzi1
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Dysregulated Immunometabolism in Chronic Granulomatous Disease is amenable to Interferon Gamma TreatmentMariolina Bruno1, Charlotte Kröger2,3, Bowen Zhang4,5, Anaísa V Ferreira1,6,7,8, Ruiqi Liu1, Rutger J Röring1, Athanasios Ziogas1, Laszlo Groh1, Viola Klück1, Simone JCFM Moorlag1, Priya A Debisarun1, Nico AF Janssen1, Diletta Rosati1, Jorge Sáiz9, Orsi Gaal1,10, Humberto J Ferreira11,12,13, Martina van Uelft2,3,11, Stefanie Warnat-Herresthal2,3, Matthias Becker3, Lisa Holsten2,3, Sophie Müller3, Michael Kraut3,11, Jonas Schulte-Schrepping2,3,11, Lorenzo Bonaguro2,3,11, Kristian Händler3,11,14, Joachim L Schultze2,3,11, Cristina Cunha6,7, Coral Barbas9, Leo AB Joosten1,10, Mihai G Netea1,2,10, Yang Li4,5, Anna C Aschenbrenner1,2,3,11, Agostinho Carvalho6,7, and Frank L van de Veerdonk1
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Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19Rainer Knoll2,3, Benjamin Krämer1, Lorenzo Bonaguro2,3, Michael ToVinh1, Jan Raabe1, Jacob Nattermann1,8, Anna Christine Aschenbrenner2,3,10, and Joachim Ludwig Schultze2,3,10
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Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19Rainer Knoll2,3, Benjamin Krämer1, Lorenzo Bonaguro2,3, Michael ToVinh1, Jan Raabe1, Jacob Nattermann1,8, Anna Christine Aschenbrenner2,3,10, and Joachim Ludwig Schultze2,3,10
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HIF-1α is required for ILC3-derived IL-22 induced by IL-18 as well as protection against C. rodentium infection. Ana Valle-Noguera1, María José Gomez-Sánchez1, Anne Ochoa-Ramos2, Patricia Yagüe Fernández2, Blanca Soler Palacios3, Virginia Zorita4, Berta Raposo Ponce5, José María González-Granado7, Julián Aragonés, and Aranzazu Cruz-Adalia1
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Genetic Factors in Early Innate Immunity to SARS-CoV-2 in the Upper Respiratory TractRanjan Ramasamy
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Interaction of Mycobacterium tuberculosis with serum amyloid A modulates the colonization of human macrophages and affects the transcriptional response of the pathogen. Malwina Kawka1, Anna Brzostek2, Katarzyna Dzitko1, Jakub Kryczka2, Radosław Bednarek3, Renata Płocińska2, Przemysław Płociński2, Dominik Strapagiel4, Justyna Gatkowska1, Jarosław Dziadek2, and Bożena Dziadek1
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Enhanced resistance to acute hepatopancreatic necrosis disease in heat-stressed Penaeus vannamei by peroxiredoxin 4 is mediated by Toll pathway activationSupitcha Wanvimonsuk1, Phattarunda Jaree2, Taro Kawai3, and Kunlaya Somboonwiwat1
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At the crossroads of IL-17 signaling in health & diseaseSarah Gaffen
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55 |
TLR2-PARP9 interaction controls type 1 interferon induction and P. gingivalis immune evasionKarthikeyan Pandi, Sarah Angabo, Luba Eli-Berchoer, and Gabriel Nussbaum
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TLR2-CD47 cross-talk: an immune evasion strategy of P. gingivalis Sarah T. Angabo, Kathikeyan Pandi, Karen Gavish, and Gabriel Nussbaum
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Role and the regulation of Kunitz-type serine protease inhibitor by its regulator, pmo-miR-bantam from the black tiger shrimp Penaeus monodon Chantaka Wongdontri
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Role of miR-750 in regulating sarcoplasmic calcium-binding protein expression in shrimp innate immune response against viral infectionKunlaya Somboonwiwat1, Nichaphat Kanoksinwuttipong1, and Phattarunda Jaree2
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Distinct mechanisms of myeloid-specific expression of the anti-ferroptotic enzyme IL4i1Leonie Zeitler, Alessandra Fiore, and Peter J Murray
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Sars-Cov-2 infection of human macrophagesStefano Gianoli1,2, Lucia Signorini 3, Luana Binaschi1,2, Serena Del Bue3, and Massimo Locati1,2
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Lipid Associated Macrophages (LAMs), a conserved features of hepatic inflammation?Federico F De Ponti, Anna Bujko, Tinne Thoné, Liesbet Martens, Anneleen Remmerie, Fleur Parmentier, and Charlotte L Scott
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RUNX1 attenuates toll-like receptor and type I interferon signaling in neutrophilsNancy A Speck1, Alexandra Zezulin1, Wenbao Yu3, Darwin Ye2, Elizabeth Howell1, Dana Bellissimo3, Ivo Touw4, Andy Minn2, and Kai Tan3
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63 |
Complement activation induces excessive TCR-independent T cell cytotoxicity in severe COVID-19Lorenzo Bonaguro1,2, Philip Georg4, Rosario Astaburuaga-Garcia5,6, Joachim L. Schultze1,2, Anna C. Aschenbrenner1,2, Charlotte Thibeault4, Florian Kurth4, Leif-Erik Sander4, Nils Blüthgen5,6, and Birgit Sawitzki6
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Inhibition of Syk kinase pathway limits pro-inflammatory cell death and immune response of HoxB8 macrophages in the in vitro model of periodontitisAlicja Płonczyńska1, Maja Sochalska1, and Jan Potempa1,2
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Importance and precaution of supplements and herbal products usage for immunity boosting during COVID-19 pandemicMerita Rumano2, Elvisa Rumano3, and Jotilda Joti2
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Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-GlucanRayoun Ramendra1,2, Mathieu Mancini3, Jose Mauricio Ayala Esparza4, Lin Tze Tung1, Stephane Isnard3, John Lin1, Jean-Pierre Routy6, Anastasia Nijnik1, and David Langlais4
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Novel method to measure activity of peptidylarginine deiminases in patient samples: application in inflammatory joint diseasesKaren Yu1, Luna Dillemans1, Mieke Metzemaekers1, Patrick Verschueren2, Lien De Somer1, and Paul Proost1
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Fibrin hydrogel modulates inflammatory responses and accelerates mouse skin wound healing Rafaela Vaz Sousa Pereira1, Mostafa EzEldeen2, Estefania Ugarte-Berzal1, Erik Martens1, Bert Malengier-Devlies1, Jennifer Vandooren1, Patrick Matthys1, and Ghislain Opdenakker1
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Viral Restriction in the Upper Airways protects Pregnant Mice against Influenza A VirusJulia Chronopoulos1,2, Erwan Pernet1, Toby K. McGovern1,2, James G. Martin1,2, and Maziar Divangahi1,2
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Hypoxia preconditioning limits neutrophil deleterious responses in a mouse model of acute lung injuryManuel A. Sanchez-Garcia1, Emily R. Watts1, Patricia Coelho1, Tyler Morrison1, Ailiang Zhang1, Andy J. M. Howden2, Pranvera Sadiku1, Sarah R. Walmsley1, and Moira K. Whyte1
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Effect of dietary protein content on innate immunity: a mechanistic and evolutionary perspectiveVaibhvi Vaibhvi and Thomas Roeder
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Azin2 promotes macrophage efferocytosis and resolution of inflammationKosuke Nagai1, Kyoung-Jin Chung1, Lydia Kalafati1, Hui Wang2, Peter J Murray3, George Hajishengallis2, Vasileia-Ismini Alexaki1, and Triantafyllos Chavakis1
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73 |
Development and Preclinical Characterization of Bispecific Monoclonal Antibody (BiMAb) for Colorectal Cancer Immunotherapy
Norah Alrishedan1, Prof. Sir Walter Bodmer1, Dr.viorica liebe1, Dr. Vita Golubovskaya2, Dr. Ali Bransi3, Dr.pablo umana3, Dr. rita mateus seidl3, and Dr. christian Klein3
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Lung commensal bacteria possess anti-inflammatory abilities and can be applied in prevention and treatment of chronic lung diseasesKatarina Veljovic2, Nikola Popovic2, Snezana Kojic1, Sofija Dunjic Manevski1, Dragica Radojkovic1, Natasa Golic2, and Marija Stankovic1
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