8th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets

Posters

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38 Ectopic expression of cancer/testis antigen NANOS3 promotes cancer invasiveness
Erkut Ilaslan, Kamila Kusz-Zamelczyk, and Jadwiga Jaruzelska
39 A CRISPR/Cas9 tool for genome-wide interrogation of essential MYC binding sites
Marta Kazimierska1, Marta Podralska3, Magdalena Żurawek1, Tomasz Woźniak4, Marta Elżbieta Kasprzyk1, Weronika Sura1, Iwona Ziółkowska-Suchanek1, Joost Kluiver2, Anke van den Berg2, Natalia Rozwadowska1, and Agnieszka Dzikiewicz-Krawczyk1
40 Exploring the role of epithelial cancer cell-derived collagen in PDAC tumorigenicity
Donatella Delle Cave, Annalisa Di Domenico, Ilaria Di Biase, Marianna Ciotola, and Enza Lonardo
41 Development and Preclinical Characterization of Bispecific Monoclonal Antibody (BiMAb) for Colorectal Cancer Immunotherapy
Norah Alrishedan
42 Juvenil, the natural immune booster affects the proliferation of tumor cells
Vanda N/A Bostikova and Klara N/A Kubelkova
43 ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer
Tom Keulers1, Alexander Koch2, Marike Van Gisbergen3, Lydie Barbeau1, Marijke Zonneveld1, Kim Savelkouls1, Roel-Germ Wanders1, Jan Bussink5, Veerle Melotte2, Monique de Jong4, and Kasper Rouschop1
44 A novel antibody targeting the tumor microenvironment antigen Fibroblast Activation Protein Alpha highlights a potential broad cancer theranostic approach.
Joseph P Gallant1,5, Hallie Hintz2, Zack Rosenkrans3, Austin Robertson1,5, Natalie Luo1, Abigail Jackson1, Jayden West1, Reinier Hernandez3,4, and Aaron LeBeau1,4
45 Liposomal nanocarriers for tumor imaging
Mohamad Ahrari
46 Effect of melanoma cell exosomes on normal and tumor-associated fibroblasts
Lucie Pfeiferová1,4, Karolína Strnadová2,3, Petr Přikryl5, Barbora Dvořánková2,3, Erik Vlčák6, Jana Frýdlová5, Martin Vokurka5, Jiří Novotný1,4, Jana Šáchová1, Miluše Hradilová1, Jan Brábek3, Jana Šmigová3, Daniel Rösel3, Karel Smetana, Jr.2,3, Michal Kolář1, and Lukáš Lacina2,3
47 Shrinkage of CD14+ monocyte/macrophage lineage cells in tumor microenvironment contributes to the expansion of CD90+ cells
Alexandros G Tzingounis1, Agapi Kataki2, Loukas Stoupis1, Ioanna Angelioudaki1, Alexandros Mitrousias1, Loukas Rentifis2, Anastasia Derventzi2, Georgios Zografos2, and Manousos M Konstadoulakis1
48 Inflammatory role of CD44v6+ cells in the interaction of pancreatic cancer with its microenvironment
Alexandros G Tzingounis1, Agapi Kataki2, Ioanna Angelioudaki1, Efthymios Koniaris3, Loukas Rentifis2, Georgios Giokas1, Georgios Zografos2, and Manousos M Konstadoulakis1
49 Tristetraprolin promotes mammary progenitor cell survival by inhibiting the TNFα-p38 signaling pathway
Micaela N Stedile1, Ángela Lara Montero1, Martín E García Solá1, Inés Beckerman1, Emilia Bogni2, Marina Ayre1, Zaira Naguila3, Omar Coso1, and Edith C Kordon2
50 A muscadine grape extract inhibits trastuzumab-resistant HER2 positive breast cancer and prevents trastuzumab-induced cardiotoxicity
Jessica D Mackert, Patricia E Gallagher, and E Ann Tallant
51 A muscadine Grape Extract Enriched in Dietary Polyphenols Reduces Breast Tumor-Associated Fibrosis in an MMTV-Transgenic Mouse Model
Ana Clara J Melo, E. Ann Tallant, and Patricia E Gallagher
52 Spatially Resolved mRNA Profiling of Vestibular Swannoma
Jana Šáchová1, Zdeněk Fík3, Miluše Hradilová1, Michaela Tesařová3, Peterková Lenka3, Monika Šťastná2, Michal Kolář1, and Jan Plzák3
53 Effects of MCL-1 inhibitor in trametinib-resistant melanoma cells on drug holiday
Paulina Tecza, Katarzyna Kluszczynska, Malgorzata Sztiller-Sikorska, Mariusz Hartman, and Malgorzata Czyz
54 Anti-CD47 immunotherapy modulates T cell bioenergetics to potentiate anti-tumor responses
Elizabeth R Stirling, Adam S Wilson, Mitra Kooshki, Liliya Yamaleyeva, Pierre L Triozzi, and David R. Soto-Pantoja
55 Enhancing tumor perfusion to improve drug delivery and tumor immune-microenvironment
Jeong Uk Choi
56 Investigation of effects of acetylsalicylic acid on pancreatic stellate cells-mediated pancreatic cancer aggressiveness.
Sıla Sığırlı3, Didem Karakaş1, and Engin Ulukaya2
57 Innate Immune Recognition, Autonomous Defence Mechanisms, and Tumorigenesis
Klara Kubelkova and Ales Macela
58 Telomere to mitochondria signaling prevents cancer initiation
Joe Nassour, Lucia G. Aguiar, Adriana Correia, Tobias Schmidt, Laura Mainz, Sara Przetocka, Gerald Shadel, and Jan Karlseder
59 FLASH radiation research at Oxford Institute for Radiation Oncology
Kristoffer Petersson
60 De novo steroidogenesis in tumor cells drives bone metastasis formation and osteoclastogenesis
Peter Benko1, Huh Joon1, Toru Hiraga2, Bidesh Mahata3, and David Gyori1
61 Tamoxifen-induced activation of Type I IFN signaling and its putative role in hormone and immunotherapy resistance of ER-positive breast cancer
Marvin A.E. Aberin1,2, Chen-Yang Shen1, Yao-Ming Chang1, and Shu-Ping Wang1,2
62 Histone H3K4 methyltransferase KMT2D/MLL4 controls leukemia cell survival through regulation of mitochondria and cellular redox homeostasis
Ta-Yu Liu1,2, Hsiao-Chin Hong2, Yu-Wen Chen2, Lan-Hsin Wang3, Yao-Ming Chang2, Chun-Wei David Chen4, Robert G. Roeder5, and Shu-Ping Wang1,2
63 Effects of Muscadine Grape Extract on prostate cancer bone metastasis
Bethany Kerr
64 Relationship between structural-mechanical properties of extracellular matrix and its ability to repopulation by cancer cells studied on decellularized organs
Anton D Pospelov1, Olga M Kutova1, Yuri M Efremov4, Albina A Nekrasova4, Daria B Trushina3, Sofia D Gefter1, Elena I Cherkasova1, Lidia B Timofeeva2, Andrey V Zvyagin4, Peter S Timashev4, and Irina V Balalaeva1