4th International Conference on the Long and the Short of Non-Coding RNAs

Posters

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39 Systematic analysis of astrocyte lineage cells after spinal cord injury unveils important regulatory long non-coding RNA Zeb2os in astrogliosis
JIA QIAN WU
40 TransCRISPR - sgRNA design tool for CRISPR/Cas9 experiments targeting transcription factor motifs
Tomasz Woźniak, Weronika Sura1, Marta Kazimierska1, Marta Elżbieta Kasprzyk1, Marta Podralska1, and Agnieszka Dzikiewicz-Krawczyk1
41 Computational methods for circRNA quantification and functional characterization
Enrico Gaffo1, Anna Dal Molin1, Alessia Buratin1, Tretti Caterina2, Cristina Borin2, Silvia Bresolin2, and Stefania Bortoluzzi1
42 Complex multiomics analysis of spinal cord injury in rat
Ruslan Klassen1,2, Daniel Zucha1,3, Sarka Benesova1,3, Eva Rohlova1,4, Peter Androvic1,5, Lucia Urdzikova-Machova6, Lukas Valihrach1, and Nataliya Romanyuk6
43 Identification and functional characterization of lncRNAs associated with response to treatment in ovarian cancer
Mohammad Ahmad1,2, Bernard LAMBERT1,2,3, Nicolas VIGNERON1,2, Emilie BROTIN1,2,4, Edwige ABEILARD1,2, Martin FIGEAC5, Cecile BLANC-FOURNIER2,6, Laurent POULAIN1,2,4, Christophe DENOYELLE1,2, and Matthieu MERYET-FIGUIERE1,2
44 Identification of ATM-dependent lncRNAs involved in DNA damage response
Marta Podralska1, Marcin Sajek2, Antonina Bielicka1, Magdalena Żurawek3, Iwona Ziółkowska-Suchanek3, Tomasz Kolenda4, Marta Kazimierska1, Marta Kasprzyk1, Weronika Sura1, Barbara Pietrucha5, Bożena Cukrowska5, Natalia Rozwadowska3, and Agnieszka Dzikiewicz- Krawczyk1
45 A functional screen to identify microRNAs relevant for immune escape in Hodgkin lymphoma
Yujia Pan, Joost Kluiver, Arjan Diepstra, and Anke van den Berg
46 Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16
Anais M Quéméner2, Laura Bachelot2, Marc Aubry 1, Marie-Dominique Galibert2, and David Gilot1
47 A high throughput screen to identify miRNAs regulating the expression of estrogen receptor and sensitivity to Tamoxifen in breast cancer
Zainab S Al Hashami1, Bert van der Vegt1, Marian Mourits2, Debora de Jong1, Annika Seitz1, Jasper Koerts1, Joost Kluiver1, and Anke van den Berg1
48 Circular ZDHHC11 is critically involved in growth of Burkitt lymphoma
Yichen Liu1, Xing Zhao1, Annika Seitz1, Debora de Jong1, Reyhaneh Ravanbakhsh2, Agnieszka Dzikiewicz-Krawczyk3, Joost Kluiver1, and Anke van den Berg1
49 IL6 signaling and long non-coding RNAs in liver cancer
Nadège W. E. Minoungou1, Aurélien Ginolhac1, Mélanie Kirchmeyer1, Rashi Halder2, and Iris BEHRMANN1
50 A functional screen to identify microRNAs acting on the NF-KB signaling pathway in Hodgkin lymphoma
Roza Cengiz, Arjan Diepstra, Jasper Koerts, Annika Seitz, Debora de Jong, Anke van den Berg, and Joost Kluiver
51 RNA Polymerase II kinetic and chromatin structure regulates defective Elp1 exon 20 splicing in an age-dependent manner
Federico Riccardi1, Giulia Romano1, Erica Bussani1, and Franco Pagani1,2
52 TAPAS (TERT antisense promoter-associated) lnc RNA regulation of TERT expression
Karen Beemon
53 Rescue of a familial dysautonomia mouse model by AAV9-Exon-specific U1 snRNA
Giulia Romano, Federico Riccardi, Erica Bussani, and Franco Pagani
54 Long non-coding RNA alteration as effect of doxorubicin drug resistance in triple negative breast cancer cell lines
Cristina A. Ciocan, Ancuta Jurj, Oana Zanoaga, Roxana Cojocneanu, Lajos Raduly, and Ioana Berindan-Neagoe
55 ZDHHC11 promotes Burkitt lymphoma cell growth by stimulation of the MEF2B-BCL6 axis
Lotteke J.Y.M Ziel-Swier1, Yichen Liu1, Marta Kazimierska2, Annika Seitz1, Debora de Jong1, Jasper A Koerts1, Agnieszka Dzikiewicz-Krawczyk2, Anke van den Berg1, and Joost Kluiver1
56 Dlx4os: a lncRNA regulating the phenotype switch in melanoma?
Ana Luisa Pedroso Ayub1, Miriam Galvonas Jasiulionis1, Eduardo Moraes Rego Reis2, Diogo Pessoa2, Frank Slack3, Ionnis Vlachos3, and Leinal Sejour3
57 Dysregulate miRNAs in Sabutoclax treated triple negative breast cancer cell lines
Laura A Pop1, Ancuta Jurj1, Lajos J Raduly1, Chiara Mattioli3, Lenart Demsar2, Ecaterina Isacescu1, Natalia Shnyanina4, and Ioana Berindan-Neagoe1
58 Dysregulated profile of microRNAs as possible biomarkers for non-small cell lung cancer, both in plasma and plasma exosomes
Lajos Zsolt Raduly1, Antonia Harangus2, Oana Zanoaga1, Ancuta Jurj1, Marioara Simon 2, Cornelia Braicu1, and Ioana Neagoe1
59 Non-canonical RNA caps affect the RNA turnover under stress conditions in E. coli
Valentina Serianni and Hana Cahová
60 Corticosterone-mediated regulation and functions of miR-218-5p in rat brain
Yogesh Dwivedi
61 The nuclear microRNA miR-29b binds to MDM2 pre-mRNA to facilitate its exon inclusion and regulation of the p53 tumor suppressor pathway
Dawn S Chandler and Matias Montes
62 m7Gp4Gm-RNA: Development of Selective CaptureSeq Method
Ondřej Nešuta1, Lenka Gahurová1, and Hana Cahová1
63 The structural diversity of mature miRNAs and its functional importance
Marta Fik-Jaskółka2, Dorota Gudanis1, and Agnieszka Belter1
64 Downregulation of miR-29b reduce triple breast cancer cells proliferation
Oana Zanoaga1, Lajos Raduly1, Vlad Morhan1, Zsofi Papi2, Ancuta Jurj1, Cristina Ciocan1, Ioana Berindan-Neagoe1, and Cornelia Braicu1
65 Roundabout of TP53-MALAT1-TAZ and their regulatory miRNAs: miR-15a-5p, miR-25-3p miR-34a-5p, and miR-141-3p in prostate cancer: Too hot to be beaten?
Liviuta Budisan1, Vlad Horia Schitcu1,2,3, Lajos Raduly1, Oana Zanoaga1, Vlad Cristian Munteanu2,3, Ancuta Jurj1, Ioan Coman3,4, Bogdan Petrut2,3, Cornelia Braicu1, and Ioana Berindan-Neagoe1
66 The biological significance of dysregulated microRNAs in prostate cancer: a common signature in tumor tissue and liquid biopsy
Andreea-Mihaela A Nutu1, Vlad Horia VH Schitcu1,2,3, Lajos L Raduly1, Oana O Zanoaga1, Cristina C Ciocan1, Vlad Cristian VC Munteanu2,3, Roxana R Cojocneanu1, Bogdan B Petrut2,3, Ioan I Coman2, Cornelia C Braicu1, and Ioana I Berindan-Neagoe1
67 Mitochondrial transport of catalytic RNAs and targeting of the organellar transcriptome in plant and human cells
Pawel Glodowicz1, Romain Val2, Joanna Rorbach, Robert N. Lightowlers3, André Dietrich2, and Katarzyna Rolle1
68 Altering the primary structure of miR-21, miR-155 and miR-181a,b,c can increase mRNA target specificity in lung cancer cells
Sergiu Chira, Liviuta Budisan, Oana Zanoaga, Lajos Raduly, Andreea Nutu, and Ioana Berindan-Neagoe
69 MODULATING 5’ UNTRANSLATED REGION SPLICING TO ENHANCE CD20 EXPRESSION AND RITUXIMAB SENSITIVITY
Zhiwei Ang1, Carolin Schmidt1, Katharina Hayer1, Joseph P Loftus2, Sarah K Tasian2, and Andrei Thomas-Tikhonenko1
70 Comprehensive analysis of cirRNA expression pattern and interaction network in glioblastoma
Julia Latowska-Łysiak1, Żaneta Zarębska1, Marcin Sajek2,3, Konrad Kuczyński1, Julia O. Misiorek1, Marek Żywicki4, Agnieszka Rybak-Wolf5, Rafał Piestrzeniewicz7, Anna M. Barciszewska6, and Katarzyna Rolle1
71 MEG3 may affect podocalyxin expression and extracellular matrix accumulation in diabetic kidney disease by modulating gene expression of key epithelial components
Ryan Castaneira, Daniel Morris, and Nikolaos Tsotakos
72 Glyceraldehyde-3-phosphate dehydrogenase, a non-canonical RNA-binding protein as a potential therapeutic target in acute myeloid leukemia
Sama Shamloo1, Eric Wang2, Alejandro Ulloa-Morales1, Yohana Ghebrechristos2, Ioannis Aifantis2, and Jochen Imig1
73 The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition
Lingyun Li and Kyrylo Krasnykov
74 qRT-PCR Analysis of the Interaction of the three RNA Types on a Set of 70 Clinical Samples of Ovarian Carcinoma
Irina Pronina, Aleksey Burdennyy, and Vitaliy Loginov
75 Distinct circular RNA and long non-coding RNA expression profiles in pediatric posterior fossa ependymomas
Ulvi Ahmadov1, Karoline Ebbesen3,4, Charlotte Udengaard1, Astrid Marie Sehested5, Jørgen Kjems3,4, Helle Broholm5, and Lasse Kristensen1
76 Interactome of HIV proteins and their host RNA interaction partners
Tinus Schynkel1, Willem van Snippenberg1,2, Kimberly Verniers2, Eric James de Bony2, Gwendolyn M. Jang3, Nevan J. Krogan3, Pieter Mestdagh2, Linos Vandekerckhove1, and Wim Trypsteen1,2
77 Targeting the biogenesis of miR-124, a potent natural anti-inflammatory miRNA, by drug candidate ABX464: a novel mechanism of action for treatment of patients with chronic inflammatory diseases
Jamal Tazi
78 Obesity and cancer: a microRNA story
Ari Meerson1,2, Hila Yehuda1,2, Yaniv Eliraz1,2, and Rahaf Salalha1,2
79 The mammalian cap-specific m6Am RNA methyltransferase PCIF1 regulates transcript levels in mouse tissues
Radha Raman Pandey1, Elena Delfino1, David Homolka1, Adriana Roithova1, Kuan-Ming Chen1, Lingyun Li1, Giulia Franco4, Cathrine Broberg Vagbø3, Emmanuel Taillebourg4, Marie-Odile Fauvarque4, and Ramesh Pillai1
80 Analysis of Circulating MicroRNA Expression in Athletes Comparing to Non-athletes Using a Hypoxia Signaling Pathway Panel
Irina Pronina1 and Pavel Postnikov2
81 Spatial profiling of circular RNAs in cancer reveals high expression in muscle and stromal cells: implications for bulk tissue analyses
Lasse S Kristensen1, Juan Luis G Rodriguez1, Ulrik Korsgaard2, Ulvi Ahmadov1, Stine M Vissing1, Morten J Olesen1, Jørgen Kjems3, and Henrik Hager2
82 Molecular role of the METTL17 RNA methyltransferase in mitochondrial ribosome biogenesis
Nancy Allahib
83 4-miRNAs panel in early-stage lung cancer diagnosis and prognosis
Paul Chiroi1, Radu Pirlog1, Ioana Rusu2, Ancuta Jurj1, Liviuta Budisan1, Cecilia Bica1, Cornelia Braicu1, Doinita Crisan, and Ioana Berindan-Neagoe1
84 Role of microRNAs in opioid addiction
Maria Mavrikaki1, Christos Miliotis1, Dimitra Karagkouni1, Tanvi Saxena1, Sabrina Zhu1, Ioannis Vlachos1, Elena Chartoff2, and Frank Slack1
85 Recent advances in small molecule inhibitors of miR-21
Qi Liang
86 Linc01268 restrains expression of the transcription factor GATA2 in immune activated human macrophages
Nils Schmerer, Harshavardhan Janga, Marina Aznaourova, and Leon N Schulte
87 The role of microRNAs in the biology of human neural stem cells
Veronika Fedorová1, Kateřina Amruz Černá1, Veronika Pospíšilová1, Jan Oppelt5, Jan Raška1, Tomáš Bárta1, Marek Mráz2,3, and Dáša Bohačiaková1,4
88 Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment
Sabine Seeler1, Liviu Ionut Moldovan1, Lars Iversen2, Henrik Hager3, Jørgen Kjems4,5, Claus Johansen2, and Lasse Sommer Kristensen1
89 Nuclear lncRNA complexes rewire systemic immune gene expression during severe COVID-19
Nils Schmerer1 and Leon N Schulte1,2
90 DIANA-miRPath v4.0 extends exploration of combined miRNA effects in cell, tissue and phenotypic contexts
Spyros Tastsoglou1,2, Giorgos Skoufos1,2,3, Marios Miliotis1,2, Dimitra Karagkouni1,2,4, Ioannis Koutsoukos1, Anna Karavangeli1,2, Filippos Kardaras1,2, and Artemis G Hatzigeorgiou1,2
91 Characterization of the ZFP36L2 RNA-binding protein in acute myeloid leukemia and normal hematopoiesis
Anna K Lee, Eric Wang, and Iannis Aifantis
92 Whole transcriptome analysis identifies coding and non-coding RNA markers of liver injury in whole body irradiated mice
Moly J Aryankalayil, Michelle Bylicky, Sunita Chopra, and C.Norman Coleman
93 From morphology to molecular pathology in early-stage lung cancer tumor microenvironment
Radu Pirlog1, Ioana Rusu2, Paul Chiroi1, Ancuta Jurj1, Liviuta Budisan1, Cecilia Bica1, Cornelia Braicu1, Doinita Crisan3, and Ioana Berindan-Neagoe1
94 Expression of lncRNAs and pluripotency genes after human chorionic gonadotropin treatment corresponds with increased proliferation and differentiation potential in-vitro and with improved hematopoiesis in-vivo. Are we far enough for therapy?
Andrei Cismaru1, Ciprian Tomuleasa2, Olga Soritau3, Cornelia Braicu1, Ancuta Jurj1, Lajos-Zsolt Raduly1, Liviuta Budisan1, Sergiu Chira1, Roxana Cojocneanu1, Raluca Muntean2, Diana Gulei2, Madalina Gherman5, Gabriel Cismaru4, and Ioana Berindan-Neagoe1
95 plasmiR database caters circulating microRNA biomarkers with experimental support
Marios Miliotis1,2, Spyros Tastsoglou1,2, Ioannis Kavakiotis1, Athanasios Alexiou1,2, Elena Gkotsi3, Anastasia Lambropoulou2, Vasileios Lygnos2, Vasiliki Kotsira1, Vasileios Maroulis3, Dimitrios Zisis2, Giorgos Skoufos1,4, and Artemis G Hatzigeorgiou1,2
96 A functional map of LncRNAs involved in Adaptation pathways of Breast Cancer Cells
Bianca Giuliani1, Chiara Tordonato2, Carmela Rubolino1, Patricio PA Fuentes1, Virginia Brancato1, Matteo J Marzi1, and Francesco Nicassio1
97 The potential of modulating the activity of exoribonucleases
Rute G. Matos1, Kenneth J. McDowall2, and Cecília M. Arraiano1
98 The effect of obatoclax mesylate on lung adenocarcinoma cells
Ancuta Jurj, Cornelia Braicu, Oana Zanoaga, Lajos Raduly, and Ioana Berindan-Neagoe
99 Intronic microRNA processing is facilitated by the P-rich domain of DROSHA
Soomin Son1,2, Baekgyu Kim1,2,3, Jihye Yang1,2, and Narry V Kim1,2
100 Unravelling the function of a short non-coding sequence in gene expression
Alexandra Moreira1,2,4, Ana Moutinho1,4, Ana Eufrásio1,2,4, Joana Azevedo1, Joana Teixeira1,2,4, Joana Machado1,3,4, Alexandre Ferreira1,3,4, Isabel Pereira-Castro1,4, and José Bessa1,4
101 microT-CNN: an avant-garde Deep Convolutional Neural Network unravels functional miRΝΑ targets beyond canonical sites
Dimitra Karagkouni1,2,3, Elissavet Zacharopoulou1,2, Anna Karavangeli1,2, Athanasios Alexiou1,2, and Artemis G Hatzigeorgiou1,2
102 Dissecting the residues responsible for the substrate specificity of Dis3L2 enzyme
Susana M. Costa, Cecília M. Arraiano, Rute G. Matos, and Sandra C. Viegas
103 Composite targeting of nuclear receptors and microRNA-21 ameliorates non-alcoholic fatty liver disease progression towards carcinogenesis in mice
Tawhidul Islam1, Pedro M Rodrigues2, Diogo Fernandes1, Mariana M Henrique1, Helena Ignačáková1, Pedro Picado1, Manuela Gaspar1, Marta B Afonso1, André L Simão1, Cecilia MP Rodrigues1, and Rui E Castro1
104 Neuronal microRNAs safeguard ER Ca2+ homeostasis and attenuate the unfolded protein response upon stress
Maria Paschou3, Panagiota Papazafiri, Chrysanthi Charalampous3, Michael Zachariadis, Skarlatos G Dedos, and Epaminondas Doxakis3
105 Comprehensive and integrative genomic characterization of malignant melanoma patients
Ioana Berindan-Neagoe 1, Simona Gurzu 3, Cornelia Braicu1, Cristina Ciocan1, Laura Pop1, Cecilia Bica 1, Rares Buiga2, Radu Pirlog 1, and Lajos Raduly1
106 microRNAs in nasopharynx and serum linked to COVID-19 severity and mortality
Marios Miliotis1,2, Spyros Tastsoglou1,2, Filippos S Kardaras1,2, Dimitra Karagkouni1,2,3,4, Anna Karavageli1,2, Gia Vatsellas5, Georgia Papadamou6, Dimitris Thanos5, Efthimia Petinaki7, and Artemis G Hatzigeorgiou1,2
107 A nanoformulated 11-microRNA pool boosting overall survival in the treatment of glioblastoma via synergistic modulation of the tumor microenvironment
Silvia Rancati1, Rui C Pereira1, Paolo Decuzzi2, and Davide De Pietri Tonelli1
108 Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus
Caterina Gasperini, Kiril Tuntevski, and Davide De Pietri Tonelli
109 A putative deoxyribonuclease activity of human ribonuclease Dicer
Marta Wojnicka, Agnieszka Szczepańska, and Anna Kurzyńska-Kokorniak
110 RNA and DNA G-quadruplexes bind to human dicer and inhibit its cleavage activity
Agnieszka Szczepanska1, Natalia Koralewska2, Kinga Ciechanowska1, Marta Wojnicka1, Maria Pokornowska1, Marek Cezary Milewski2, Dorota Gudanis3, Daniel Baranowski3, Chandran Nithin4, Janusz Marek Bujnicki4,5, Zofia Gdaniec3, Marek Figlerowicz2, and Anna Kurzynska-Kokorniak1
111 Characterization of the biochemical activities of the human Dicer helicase domain
Kinga Ciechanowska and Anna M. Kurzyńska-Kokorniak
112 Rewiring of RNA-chromatin interactions during adipocyte differentiation
Alessandro Bonetti1 and Federico Agostini2
113 MicroRNA loss drives tumor development in murine models of angiosarcoma
Annaleigh Powell-Benton1, Anthony Murphy1, Emma Terwilliger1, Nadia Lanman2, and Jason A Hanna1
114 Revealing evidence of DNA:DNA:RNA triplex and DNA:RNA heteroduplex formation of lncRNAs by NMR spectroscopy
Jasleen Kaur Bains1,2, Nina M. Krause1,2, Christian Richter1,2, Hendrik R.A. Jonker1,2, Matthias S. Leisegang3, Ralf P. Brandes3, and Harald Schwalbe1,2
115 Inter-organellar nucleic acid communication by a mitochondrial tRNA regulates nuclear transcription
Christopher Rouya, King Yambire, and Sohail F Tavazoie
116 NON-CANONICAL EXON USAGE IN PEDIATRIC LEUKEMIA: IMPLICATIONS FOR CHEMORESISTANCE
Manuel Torres-Diz1, Clara Reglero-Gomez6, Catherine Falkenstein2, Zhiwei Ang1, Priyanka Sehgal1, Caleb Radens5, Yoseph Barash5, Sarah Tasian22,4, Adolfo Ferrando6, and Andrei Thomas-Tikhonenko1,2,3,4
117 TP53 mutation-associated and copy-dependent KDM7A-DT expression affects DNA repair and promotes invasive breast cancer progression
Vasileios Gouzouasis1, Antonis Giannakakis1,2,3, Margaritis Tsifintaris1, Charisios Triantafyllou1, Ghim Siong Ow2, Csaba Papp4, Anna Ivshina2, and Vladimir Kuznetsov2,4