17th International Conference on Complement Therapeutics

Program - Sunday, May 11

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 
    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport
    Please note that Crete has two airports. You want to arrive at the Heraklion International Airport (code: HER) and take a taxi from the airport to the hotel (~80 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively Chania International Airport (CHQ) is a two-hour drive to the Conference Center.

    Accommodation Tax
    An accommodation tax of € 10.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations
    Accommodations for the conference are at the Kalimera Kriti Hotel.  The hotel is located in Sissi, 40 km from Heraklion International Airport.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in 
    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:00 pm on the first day should make alternative dinner arrangements.

    Conference Venue
    The Kalimera Kriti Conference Center is located at the hotel. 

    Handicapped Accessibility
    The site is fully handicapped accessible.

    Oral Presentations
    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    Archaeological Site of Knossos and City Tour
    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast
    Breakfast for registered participants and registered accompanying persons will be served at the Kalimera Kriti main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions
    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions
    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer 
    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation
    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa/ETIAS
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date. Starting 2025 you may need to apply for an ETIAS.
    https://www.etiaseu.com/us-citizens/etias-greece

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information
    Animals are not permitted on site.
    Badges are required for admission to all events.
    All Aegean Conferences events are no smoking, no e-cigarretes, no vaping, etc. 

    No Photographs and Recording Devices 
    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 
    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

     

Sunday, May 11

08:00 AM - 08:50 AM
Breakfast
08:50 AM - 09:00 AM
Welcome and Opening Remarks - John Lambris (on behalf of the Organizing Committee)
SESSION I Structural insights - mechanisms of activation and regulation
Chairs: Christine Gaboriaud and Brian Geisbrecht
09:00 AM - 09:20 AM
1
Unveiling the unique interaction mechanism of herpes simplex virus 2 glycoprotein C with C3b
Moises H Rojas Rechy1, Doina Atanasiu2, Lauren M Hook3, Tina M Cairns2, Wan Ting Saw2, Neil A Ranson1, Friedman M Harvey3, Gary H Cohen2, and Juan Fontana4
09:20 AM - 09:40 AM
2
Viral teachings on complement regulation
Arvind K Sahu
09:40 AM - 10:00 AM
3
Activation of native C3 without proteolytic cleavage induced by phosphatidyl serine containing membranes.
David Eikrem1, Kristina Nilsson Ekdahl,, Karin Fromell1, and Bo Nilsson1
10:00 AM - 10:20 AM
4
Complement C1 proteases as possible new therapeutic targets in diseases
Véronique Rossi1, Nolwenn Haut3, Nicole M Thielens1, and Christine Gaboriaud2
10:20 AM - 10:35 AM
5
Sex Chromosome Regulation of Complement System Activity: Evidence for Post-Transcriptional Control of C3 and C4 Levels
William A Barr
10:35 AM - 11:15 AM
Coffee Break and Poster Viewing (Odd Numbers)
SESSION II Therapeutic complement inhibitors: from bench to bedside
Chairs: Anna Schubart Wellensiek and Daniel Ricklin
11:15 AM - 11:35 AM
6
Therapeutic complement modulation at the forefront of novel immunotherapies: Misconceptions, myths, and novel insights
John D Lambris
11:35 AM - 11:55 AM
7
Inhibiting the Complement Classical Pathway by Blocking Activation of the C1r Zymogen
Huiquan Duan1, Wei Wu2, Ping Li2, Samuel Bouyain3, Brandon L Garcia1, and Brian V Geisbrecht1
11:55 AM - 12:15 PM
8
Keeping host defense on a leech: Gigastasin as a versatile template for designing complement and coagulation system modulators
Aleksandra Blagojevic1, Peter Rüthemann1, Kevin Widmer1, Florian Meyer1, Sofia Pinheiro1, Said Rabbani1, Rolf Spirig2, Kirsten Guse2, Martin Smiesko1, Markus Lill1, and Daniel Ricklin1
12:15 PM - 12:35 PM
9
Complement Alternative Pathway Inhibitors for Hemocompatibility of Nanoparticles in Multiple Animal Species.
Dmitri Simberg
12:35 PM - 12:50 PM
10
The story of empasiprubart (ARGX-117), a long acting inhibitory C2 antibody, from bench to MMN patients
Inge Van de Walle and ARDA Developement team
12:50 PM - 01:10 PM
11
Iptacopan (Fabhalta) for the treatment of complement-mediated diseases
Anna Schubart
01:10 PM - 01:25 PM
12
Augmenting cytotoxicity of pathogen-specific antibodies that initiate complement activation independent of the classical pathway
Wilhelm J Schwaeble
01:25 PM - 01:40 PM
13
TBA - Mastellos
Dimitris Mastellos
01:40 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions (Buses Depart from Hotel Lobby)