Aegean Conferences

5th International Conference on the Long and the Short of Non-Coding RNAs

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!

General Information

No details.

Monday, June 17

06:30 PM - 07:30 PM

Conference Registration

07:30 PM - 10:30 PM

Welcome Reception and Dinner

Tuesday, June 18

08:00 AM - 08:50 AM

Breakfast

08:50 AM - 09:00 AM

Welcome and Opening Remarks

Session I: ncRNAs throughout evolution

Chair: Simon Conn

09:00 AM - 09:20 AM

PROGRAM PRESENTATION: FEBS activities and programs
Beata G. Vertessy

09:20 AM - 09:45 AM

RNA quality control pathways in prokaryotes
Cecília Maria Arraiano

09:45 AM - 10:10 AM

RNA-based regulation in stress response and virulence control of pathogenic Epsilonproteobacteria
Cynthia M. Sharma

10:10 AM - 10:35 AM

Noncoding RNA-mediated complex genome editing in the ciliate Oxytricha
Laura Landweber

10:35 AM - 11:00 AM

RNA-directed transposon silencing
Dónal O'Carroll

11:00 AM - 12:00 PM

Coffee Break and Poster Viewing (Poster #49-#78)

Session II: short RNA biogenesis and regulation

Chair: Joana Vidigal

12:00 PM - 12:25 PM

Regulation of mRNA translation and decay
David Bartel

12:25 PM - 12:50 PM

Oncogenic roles of RNA-modifying enzymes
Richard I Gregory

12:50 PM - 01:15 PM

Mechanisms involved in miRNA export and import
Andrea Kasinski

01:15 PM - 01:35 PM

BREAKING NEWS: Dynamic shuttling of AGO2 to the nucleus relieves microRNA repression
Krystal C Johnson², Audrius Kilikevicius², Cristina Hofman², Jiaxin Hu², Yang Liu², Selina Aguilar², Jon Graswich², Yi Han³, Tao Wang³, Jill M Westcott⁴, Rolf A Brekken⁴, Lan Peng⁴, Georgios Karagkounis⁴, and David R Corey²

01:35 PM - 02:00 PM

AGO unchained: beyond the miRNA pathway
Joana Vidigal

02:00 PM - 03:00 PM

Lunch and Informal Discussions

03:00 PM - 07:00 PM

Informal Discussions

07:30 PM - 11:00 PM

Dinner and Informal Discussions (Buses depart from hotel lobby)

Wednesday, June 19

08:00 AM - 09:00 AM

Breakfast

Session III: short RNAs in development & disease

Chair: Francesco Nicassio

09:00 AM - 09:25 AM

Divergent Roles of Dicer’s Helicase Domain in Antiviral Defense
Brenda Bass

09:25 AM - 09:50 AM

Circular RNAs in Endogenous RNA-directed DNA damage
Vanessa M Conn and Simon J Conn

09:50 AM - 10:15 AM

Harmony of Non-Coding RNAs: Unveiling Their Role in Aging, Neurodegeneration, and Epigenetic Regulation
Jun-An Chen

10:15 AM - 10:40 AM

Computational analyses of microRNA functions
Artemis Hatzigeorgiou

10:40 AM - 11:00 AM

BREAKING NEWS: Non-coding RNAs and genome organization control the dynamics of gene expression during development
Philippe J Batut¹ and Michael S Levine²

11:00 AM - 12:00 PM

Coffee Break and Poster Viewing (Poster #49-#78)

Session 4: mRNA metabolism

Chair: Eric Wang

12:00 PM - 12:25 PM

Nonsense-mediated mRNA decay in human health and disease
Lynne E. Maquat

12:25 PM - 12:50 PM

RNA-quality control of gene expression
Javier F Caceres

12:50 PM - 01:15 PM

Aberrantly spliced surface proteoforms in cancer
Andrei Thomas-Tikhonenko

01:15 PM - 01:40 PM

RNA Isoform regulation across mammalian brain regions, post-natal development and species
Hagen Tilgner

01:40 PM - 02:00 PM

BREAKING NEWS: Single-cell nanopore sequencing uncovers coding and non-coding isoform dynamics in the aging brain
Emmanouil Maragkakis

02:00 PM - 03:00 PM

Lunch and Informal Discussions

03:00 PM - 07:00 PM

Informal Discussions

07:30 PM - 11:00 PM

Dinner and Informal Discussions (Buses depart from hotel lobby)

Thursday, June 20

08:00 AM - 09:00 AM

Breakfast

Session V: lncRNA in development & disease

Chair: Daniel Cifuentes

09:00 AM - 09:25 AM

Aging-associated non-coding RNAs
Myriam Gorospe

09:25 AM - 09:50 AM

New functions for noncoding RNAs in mammals
Josh Mendell

09:50 AM - 10:15 AM

Cis-acting gene regulation by long noncoding RNAs
Igor Ulitsky

10:15 AM - 10:40 AM

Malat1 lncRNA and lung cancer microenvironment
Nadya Dimitrova

10:40 AM - 11:00 AM

BREAKING NEWS: Long non coding RNAs modulate alternative splicing regulations in the plant transcriptome
Martin Crespi, Michel Heidecker, AUrelie Christ, Celine Charon, and Jeremie Bazin

11:00 AM - 12:00 PM

Coffee Break and Poster Viewing (Poster #78-#103)

Session VI: Novel technologies for RNA studies

Chair: Ophir Shalem

12:00 PM - 12:25 PM

RNA in Space
Nikolaus Rajewsky

12:25 PM - 12:50 PM

mRNA Decay
Zissimos Mourelatos

12:50 PM - 01:15 PM

glycoRNA biology on the cell surface
Ryan A Flynn

01:15 PM - 01:35 PM

BREAKING NEWS: RBPscan: Quantitative and sequence-specific measurement of RNA-protein interactions in vivo
Dmitry Kretov, Thora McIsaac, Imrat Imrat, Owen Sanborn, Elaine Park, and Daniel Cifuentes

01:35 PM - 02:00 PM

Pooled gene tagging and in-situ sequencing for unbiased exploration of protein-RNA subcellular landscape
Ophir Shalem

02:00 PM - 03:00 PM

Lunch and Informal Discussions

03:30 PM - 08:00 PM

Guided Tour of Old Town Chania (Buses Depart from Hotel Lobby)

08:00 PM - 11:00 PM

Dinner and Informal Discussions (Buses do not return or pickup from the hotel prior to dinner)

Friday, June 21

08:00 AM - 09:00 AM

Breakfast

Session VII: Short presentations by FEBS and Aegean Conferences Awardees

Chair: Krystal Johnson

09:00 AM - 09:20 AM

BREAKING NEWS: Dinucleoside polyphosphate RNA capping in bacteria and mammalian cells.
Hana Cahova

09:20 AM - 09:40 AM

BREAKING NEWS: Unraveling the impact of chromatin dissociation dynamics of lncRNAs in gene expression regulation
Evgenia Ntini

09:40 AM - 09:50 AM

FEBS TRANS-YTF AWARD: MicroRNAs orchestrate the tempo of aging
Xin Le Yap^1,², Chung-Jung Li¹, Shih-Hsin Chang¹, Ho-Chiang Hsu¹, and Jun-An Chen¹

09:50 AM - 10:00 AM

FEBS YTF AWARD: Roles and therapeutic impact of miR-92a-1-5p in chronic myeloid leukemia
Joanne Péters¹, Emeline Bollaert¹, Melissa Claus¹, Anne-Sophie Cloos¹, Jean-Baptiste Demoulin¹, and Violaine Havelange^1,²

10:00 AM - 10:10 AM

AEGEAN AWARD: miRNA-503 inhibition shows anticancer effects in mesothelioma
Miriam Piccioni¹, Virginia Campani², Giuseppe De Rosa², Mirella Tanori³, Mariateresa Mancuso³, Stefania Filosa¹, Alfonso Baldi⁴, and Stefania Crispi¹

10:10 AM - 10:20 AM

AEGEAN AWARD: Circular ZDHHC11 supports Burkitt Lymphoma growth independent of its miR-150 binding capacity
Shiyun Hu¹, Yichen Liu¹, Xing Zhao¹, Leonie Piek¹, Annika Seitz¹, Annie Hooijsma¹, Reyhaneh Ravanbakhsh¹, Sofia Sheveleva¹, Debora de Jong¹, Jasper Koerts¹, Agnieszka Dzikiewicz-Krawczyk², Anke van den Berg¹, Lotteke Ziel-Swier¹, and Joost Kluiver¹

10:20 AM - 10:30 AM

AEGEAN AWARD: A microRNA-focused CRISPR-Cas9 screen identifies mir-483 as an essential gene in prostate cancer.
Jonathan Tak-Sum Chow¹, Ayeisha Desjardins¹, Daniel KC Lee¹, Norman J Fu¹, Stephanie Chau¹, Iulia A Grigore¹, Martino M Gabra¹, and Leonardo Salmena^1,²

10:30 AM - 10:40 AM

AEGEAN AWARD: Canonical and non-canonical Target-Directed MicroRNA Degradation controls cell fitness and transcriptional plasticity in breast cancer
Matteo J Marzi¹, Carmela Rubolino¹, Manfredi D'Onghia¹, Chiara Tordonato², Bianca Giuliani¹, and Francesco Nicassio¹

10:40 AM - 10:50 AM

AEGEAN AWARD: Capture me if you can: Full-length annotation of lncRNAs in the zebrafish genome
Monika Kwiatkowska¹, Sasti Gopal Das¹, Silvia Carbonell-Sala², Gazaldeep Kaur², Roderic Guigó Serra², and Barbara Uszczyńska-Ratajczak¹

10:50 AM - 11:00 AM

FEBS YTF AWARD: Modulation of DMD mRNA stability via kinetic coupling leads to changes in UTRN abundance
Lara Falucci, Christopher M. Dooley, Justin Martinez, Cansu Cirzi, and Didier Y. R. Stainier

11:00 AM - 11:10 AM

FEBS YTF AWARD: Long noncoding RNA OIP5-AS1 in breast cancer cells
Elzbieta Wanowska, Izabela Makalowska, and Michal Szczesniak

11:10 AM - 11:20 AM

FEBS YTF AWARD: Unveiling the mechanism of action of MEG3 as a tumor suppressor
Karina B Sabalette¹, Liubov Makarova¹, Isabel Chillon², and Marco Marcia¹

11:20 AM - 11:30 AM

FEBS YTF AWARD: Genome-wide profiling of lncRNAs revealed their important role in transitioning among neoplastic subpopulations in childhood ependymoma
Stine M Vissing, Ulvi Ahmadov, Charlotte W Udengaard , Kim-Gwendolyn Dietrich , Stine E Asmussen , and Lasse S Kristensen

11:30 AM - 12:00 PM

Coffee Break and Poster Viewing (Poster #78-#103)

Session VIII: RNA biomarkers & therapeutics

Chair: Nadya Dimitrova

12:00 PM - 12:20 PM

BREAKING NEWS: LncRNA GRASLND affects Melanoma Cell Growth, Phenotypic Switch and Immunogenicity by Modulation of dsRNA Innate Immunity Sensor PKR
Kim Denise Fischer¹, Lin Christina Qiu¹, Shashank Tiwari¹, Stavroula Petroulia¹, Beatrice Thier², Annette Paschen², and Jochen Imig¹

12:20 PM - 12:45 PM

Enhancing in vivo DNA and RNA Editing
Prashant Mali

12:45 PM - 01:10 PM

Development of Short Oligonucleotides to Inhibit the Functions of RNA-Binding Proteins
Jonathan Hall

01:10 PM - 01:35 PM

Chemical engineering of therapeutic RNAs
Anastasia Khvorova

01:35 PM - 02:00 PM

Preclinical Screening of Splice-Switching ASO
Adrian R. Krainer

02:00 PM - 02:05 PM

Closing Remarks

02:05 PM - 03:00 PM

Lunch and Informal Discussions

02:05 PM - 03:00 PM

Informal Discussions

07:30 PM - 11:00 PM

Farewell Dinner and Travel Awards

Saturday, June 22

08:00 AM - 10:00 AM

Breakfast

10:00 AM - 12:00 PM

Departure