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GENERAL INFORMATION |
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Accommodations The conference participants will be staying at the Double Tree Hotel, which is located in Kardamena, 11 km from the airport.
Arrival and Check-in Attendees are expected to arrive/check-in on Sunday after 3:00 pm local time. Registered participants arriving after 10:30 pm Sunday night should make alternative dinner arrangements. Conference Venue The Double Tree Conference Center is located at the hotel.
Handicapped Accessibility The site is fully handicapped accessible.
Posters Posters should be mounted Sunday, June 15 between 7:00 – 8:00 PM, on the designated boards and dismounted at the closing of the conference. The dimensions of the boards are 90 cm wide X 120 cm high. Adhesive tape for mounting the posters on the boards will be available at the poster area.
Oral Presentations Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session. The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.
City Tour Buses for the city tour will depart from the hotel front lobby on Wednesday, June 18 at 1:45 pm. Badges are required for participation. BreakfastBreakfast for registered participants and registered accompanying persons will be served at the Double Tree Hotel main restaurant during the hours scheduled in this program.
Lunches/Informal Discussions Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant. Badges are required for admission.
Dinners/Informal Discussions Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting. Please contact info@aegeanconferences.org.
Internet, Phone, & Computer Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.
Certificate of Participation A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session.
Other Information Animals are not permitted on site. Badges are required for admission to all events. All Aegean Conferences events are non-smoking.
No Photographs and Recording Devices Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations.
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Sunday, June 15 |
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6:00-8:00 PM |
Conference Registration at Hotel Lobby |
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8:00 PM |
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Welcome Reception/Dinner |
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Monday, June 16 |
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7:30 AM |
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Breakfast |
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8:30 AM |
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Welcome & Opening Remarks |
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Session I |
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Myelopoiesis |
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Chair: Joe Lorenzo |
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8:45 AM |
1 |
TBA |
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Frederic Geissmann |
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9:15 AM |
2 |
Transcription factors with a backbone: the role of NFATs in vertebrate skeletal biology |
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Antonios O Aliprantis |
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9:45 AM |
3 |
Studies of the ability of injected osteoclast precursor cells to differentiate into mature osteoclasts in the bones of mice during normal growth, inflammatory arthritis and fracture repair |
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CE Jacome-Galarza, SK Lee, G Schett, HL Aguila, and Joseph A Lorenzo |
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10:15 AM |
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Coffee Break |
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Session II |
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Osteoblasts and Arthritis |
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Chair: Georg Schett |
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10:45 AM |
4 |
Antibodies linking immune activation to bone loss |
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Georg Schett |
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11:15 AM |
5 |
Oxysterols and EBI2 guide osteoclast precursors to the endosteum and regulate bone mass homeostasis |
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Erin P Nevius, Flavia Pinho, Huiyan Jin, Kristina Nadrah, Mark Horowitz, Ze Wang, Junichi Kikuta, Masaru Ishii, and João P Pereira |
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11:45 AM |
6 |
miR-146a deficiency in Ly6Chigh monocytes contributes to pathogenic bone loss during inflammatory arthritis |
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Meryem Ammari, Isabelle Duroux-Richard, Jessy Presumey, Clara Ponsolles, Christine Roubert, Gautier Rossignol, Virginie Escriou, Christian Jorgensen, and Florence Apparailly |
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12:00 PM |
7 |
Constitutive activation of ß-catenin in osteocytes controls bone homeostasis, bone growth and bone strength |
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Zong Zhaowen, Sixu Chen, Bo Zhang, and Jianquan Feng |
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12:15 PM |
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Coffee Break & Poster Session |
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1:30 PM |
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Lunch / Informal Discussions Lunch will be served only after the poster session |
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7:30 PM |
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Dinner / Informal Discussions at a local Greek Taverna Buses depart from the hotel lobby at 7:30 PM |
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Tuesday, June 17 |
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7:30 AM |
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Breakfast |
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Session III |
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Transcriptional Regulation |
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Chair: Hiroshi Takayanagi |
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8:30 AM |
8 |
Transcriptional regulation of osteoclastogenesis |
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Takeshi Miyamoto |
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9:00 AM |
9 |
Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclasts |
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Jung Ha Kim, Dennis DM O’Leary, and Nacksung Kim |
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9:30 AM |
10 |
Cell communication in osteoimmunology |
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Hiroshi Takayanagi |
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10:00 AM |
11 |
Continuous PTH treatment induces bone loss through T cells produced IL17 |
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Roberto Pacifici |
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10:30 AM |
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Coffee Break |
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10:45 AM |
12 |
NIK’ing the Bone: Controlling Pathological Osteoclast Activation |
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Deborah Novack |
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11:15 AM |
13 |
IL-23 induces spondyloarthropathy by acting on RORγt+ CD3+ CD4- CD8- entheseal resident T cells |
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Daniel J Cua |
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11:45 AM |
14 |
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis |
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Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh-hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A Bluestone, and Hiroshi Takayanagi |
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12:00 AM |
15 |
RANKL licenses T lymphocytes to enter into the central nervous system in experimental autoimmune encephalomyelitis |
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Matteo M Guerrini, Kazuo Okamoto, Tomoki Nakashima, and Hiroshi Takayanagi |
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12:15 PM |
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Coffee Break & Poster Session |
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1:30 PM |
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Lunch / Informal Discussions Lunch will be served only after the poster session |
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7:30 PM |
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Dinner / Informal Discussions at a local Greek Taverna Buses depart from the hotel lobby at 7:30 PM |
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Wednesday, June 18 |
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7:30 AM |
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Breakfast |
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Session IV |
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Innate Immunity and Epigenetics |
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Chair: Lionel Ivashkiv |
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8:30 AM |
16 |
Regnase-1, a ribonuclease involved in the control of immune responses |
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Shizuo Akira |
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9:00 AM |
17 |
The macrophage epigenome and the control of basal and inducible gene expression |
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Gioacchino Natoli |
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9:30 AM |
18 |
Epigenetic regulation of osteoclastogenesis |
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Lionel B Ivashkiv |
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10:00 AM |
19 |
Genome-wide comprehensive analysis reveals the critical cooperation of TGF-β-Smad pathway with c-Fos in RANKL-induced osteoclastogenesis |
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Sakae Tanaka and Omata Yasunori |
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10:30 AM |
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Coffee Break |
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10:45 AM |
20 |
Role of DNA sensors in a novel model of autoimmunity and bone erosion |
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Ellen M Gravallese, R Baum, S Sharma, A Rothstein, and K A Fitzgerald |
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11:45 AM |
21 |
Permissive signals from the commensal microbiota poise expression of proinflammtory cytokine genes in mononuclear phagocytes |
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Leif Rogell, Stephanie C Ganal , and Andreas Diefenbach |
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12:00 PM |
22 |
TLR signaling through TIRAP/Mal Mediates Inflammatory Osteolysis |
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C Bechtel, SJ MacInnes, J Gebhart, J Tatro, E Kiss-Toth, JM Wilkinson, and Ed M Greenfield |
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12:15 PM |
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Lunch / Informal Discussions |
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1:45 PM |
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Sightseeing and a guided walking tour in old city of Kos |
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7:30 PM |
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Dinner / Informal Discussions at a local Greek Taverna Dinner to follow the tour. Buses do not return prior to dinner |
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Thursday, June 19 |
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7:30 AM |
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Breakfast |
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Session V |
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Up and Coming |
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Chair: Yongwon Choi |
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8:30 AM |
23 |
Osteocyte Control of Bone Remodeling |
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Charles A OBrien |
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9:00 AM |
24 |
New insights on bone biology from exome sequencing of osteopetrotic patients with atypical presentations |
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Eleonora Palagano, Alessandra Pangrazio, Dario Strina, Alessandro Puddu, Manuela Oppo, Maria Valentini, Gianmauro Cuccuru, Paolo Uva, Andrea Angius, Paolo Vezzoni, Anna Villa, and Cristina Sobacchi |
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9:30 AM |
25 |
ERα in osteoblasts is required for cancellous mass accrual and attenuates bone’s anabolic response to mechanical loading |
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Marjolein CH Van der Meulen, and Katherine M Melville |
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10:00 AM |
26 |
TBA |
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Mary Nakamura |
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10:30 AM |
27 |
Bone Marrow Adipogenesis |
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Ryan Berry, Rose Webb, Tracy Nelson, Yougen Xi, Aimee E Belak, Jackie A Fretz, Casey R Doucette, Joshua N VanHoutan, Nancy Troiano, Chris D Church, Clifford J Rosen, Matthew S Rodeheffer, and Mark C Horowitz |
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11:00 AM |
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Coffee Break |
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Session VI |
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ShortTalks |
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Chair: Yongwon Choi |
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11:30 AM |
28 |
Targeting Epigenetic Regulation by BET bromodomain Protein Inhibits Osteoclastogenesis and Inflammatory Bone Resorption |
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Kyung-Hyun Park-Min, Elisha Lim, Min Joon Lee, Marjolein van der Meulen, Nicholas Smithers, Rab K Prinjha, and Lionel B Ivashkiv |
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11:45 AM |
29 |
Regulation of erythropoiesis by an EF-hand protein identified as a regulator of osteoclastogenesis |
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Kazuo Okamoto, Mikihito Hayashi, Tomoki Nakashima, and Hiroshi Takayanagi |
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12:00 PM |
30 |
MFG-E8 homeostatically regulates inflammatory bone loss in vivo |
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Toshiharu Abe, Shin Jieun, Hosur Kavita, Udey C Mark, Chavakis Triantafyllos, and Hajishengallis George |
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12:15 PM |
31 |
HIF prolyl hydroxylase 2 (PHD2) controls bone homeostasis through HIF2alpha - a novel player in osteohematology and osteoimmunology |
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Martina Rauner, Kristin Franke, Lorenz C Hofbauer, and Ben Wielockx |
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12:30 PM |
32 |
Glucocorticoids regulate sclerostin levels in vitro and in vivo |
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Elena Tsourdi, Sylvia Thiele, Alexander Rauch, Jan P. Tuckermann, Karolien De Bosscher, Anke Hannemann, Henri Wallaschofski, Lorenz C. Hofbauer, and Rauner Martina |
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12:45 PM |
33 |
Wnt5a up-regulates the expression of Lrp5/6 during osteoblastogenesis |
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Masanori Okamoto, Nobuyuki Udagawa, Teruhito Yamashita, Shunsuke Uehara, Hiroyuki Kato, Naoto Saito, Naoyuki Takahashi, and Yasuhiro Kobayashi |
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1:00 PM |
34 |
Do immune cells impair regeneration of bone? |
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Katharina Schmidt-Bleek, Alessandro Serra, Daniel Toben, Hanna Schell, Hans-Dieter Volk, and Georg N Duda |
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1:15 PM |
35 |
Genome-wide comprehensive analysis demonstrates that PU.1 cooperates with NFATc1 in osteoclastogenesis |
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Naohiro Izawa, Hiroyuki Aburatani, and Sakae Tanaka |
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1:30 PM |
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Closing Remarks |
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1:45 PM |
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Lunch / Informal Discussions |
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7:30 PM |
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Farewell Dinner |
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Friday, June 20 |
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7:30 AM |
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Breakfast |
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Departure |
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POSTERS |
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36 |
Potent Anti-Osteoporosis of Teriparatide in Ovariectomized(OVX) rats: the role of IL-17 |
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Shunping Wang |
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37 |
Analysis of hematopoietic stem cell fate maintenance and differentiation due to dysregulation of the Wnt signaling antagonist, sclerostin |
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Jennifer O Manilay |
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38 |
Ankylosing spondylitis in women, particular features |
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Leysan I Miasoutova and Svetlana A Lapshina |
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39 |
Arthritogenic interactions between lymphocytes and synovial fibroblasts. |
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Martin Böttcher, Adelheid Korb-Pap, Federica Madarena, Georg Schett, Thomas Pap, and Thomas Kamradt |
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40 |
Bone and immune system interaction in multiple myeloma-bone disease: The role of light |
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Isabella Gigante, Angela Oranger, Grazia Taurino, Teresa Mongelli, Giorgio Mori, Claudia Carbone, Anna Mestice, Bruna Daraia, Giuseppe Ingravallo, Anna Napoli, Rita Rizzi, Alberta Zallone, Sivia Colucci, Giorgina Specchia, Maria Grano, and Giacomina Brunetti |
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41 |
C1Q is absolutely required for disease development in experimental arthritis |
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Matthieu Ribon, Julie Mussard, Marina Botto, Marie-Christophe Boissier, and Patrice Decker |
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42 |
Cross talk between bone and the immune system: genes controlling bone remodeling are important for severity of Collagen Induced Arthritis |
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Samra Sardar, Alish Kerr, Daniëlle Vaatjes, and Åsa Andersson |
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43 |
Different culture conditions modulate immunological properties of adipose stem cells |
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Mimmi Patrikoski, Jyrki Sivula, Heini Huhtala, Mika Helminen, Fanny Salo, Bettina Mannerström, and Susanna Miettinen |
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44 |
Dynamics of bone marrow survival niches for long-lived plasma cells |
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Sandra Zehentmeier, Katrin Roth, Zoltan Cseresnyes, Özen Sercan, Raluca Niesner, Andreas Radbruch, and Anja E. Hauser |
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45 |
Dysregulated osteoclastogenesis is related to natural killer T cell dysfunction in rheumatoid arthritis |
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Yong-Wook Park, Seung-Jung Kee, and Nacksung Kim |
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46 |
Effects of teripatide on vertebral and femoral strength assessed by finite element analysis of clinical computed tomography scans in Rheumatoid arthritis patients |
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Kumiko Ono, Satoru Ohashi, Yuho Kadono, Tetsuro Yasui, Kazuya Isawa, Naoko Shoda, Toshiyuki Oka, and Sakae Tanaka |
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47 |
Fc-glycosylation determines osteoclastogenic activity of immune complexes |
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Ulrike Harre, René Pfeifle, Sabine Frühbeißer, Khaled Amara, Holger Bang, Anja Lux, Franziska Gröhn, Vivianne Malmström, Lars Klareskog, Gerhard Krönke, Roland Kocijan, Falk Nimmerjahn, René EM Toes, Yoann Rombouts, Martin Herrmann, Hans-Ulrich Scherer, and Georg Schett |
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48 |
Foreign body giant cells form actin rings but do not have the capacity to resorb bone |
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Bas Ten Harkel, Ton Schoenmaker, Teun J de Vries, and Vincent Everts |
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49 |
Frequency of CD8+ T cells determines bone fracture healing outcome |
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Claudia Schlundt, Simon Reinke, Sven Geissler, Hanna Schell, Hans-Dieter Volk, Georg N Duda, and Katharina Schmidt-Bleek |
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50 |
Glucocorticoids suppress inflammation in arthritis by the glucocorticoid receptor in non-hematopoietic cells and impair bone quality by distinct mechanisms |
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Ulrike Baschant, Stephan Culemann, Mascha Koenen, Martina Rauner, Markus Seibel, Lorenz Hofbauer, Hong Zhou, and Jan Tuckermann |
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51 |
Human mesenchymal stromal cells survive in vivo and play both direct and paracrine actions to improve bone regeneration |
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Nathalie Chevallier |
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52 |
Hypertension and experimental periodontitis change osteoblast phenotype in rats. In vivo and in vitro study. |
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Caril Constante Ferreira do Amaral, Thamine Landim de Barros, Victor G Balera, Antonio H Chaves-Neto, and Sandra HP Oliveira |
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53 |
Identification of a novel mutation in heritable osteonecrosis of the femoral head |
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Tracy Wang, Mah Wayne, Harvey Edward, Majewski Jacek, Rosenblatt David, and Séguin Chantal |
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54 |
Immune response during bone healing in a murine fracture model with osteomyelitis: role of biomechanical stability |
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Marina Sabaté Brescó, Katharina Kluge, Mario Ziegler, Geoff Richards, Liam O’Mahony, and Fintan Moriarty |
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55 |
LSD1-Mediated Demethylation of Histone H3 Lysine 9 Contributes to Interleukin 1-Induced Microsomal Prostaglandin E Synthase-1 Expression in Human Osteoarthritic Chondrocytes |
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Fatima Ezzahra El Mansouri, Salwa-Sarah Nebbaki, Mohit Kapoor, Hassan Afif, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Mohamed Benderdour, and Hassan Fahmi |
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56 |
Macrophage multinucleation by TLR ligands and TNF via cell cycle regulation |
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Antigoni Triantafyllopoulou, Laura Bergdolt, Indrajit Nanda, Thomas Haaf, and Philipp Henneke |
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57 |
Mechanical Stimulation of polycystin-1 in human osteoblastic cells potentiates the JAK/STAT signalling axis |
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Georgia Dalagiorgou, Christina Piperi, Konstantinos A Papavassiliou, Christos Adamopoulos, Athanassios G Papavassiliou, and Efthimia K Basdra |
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58 |
Mechanism of action of mesenchymal stromal stem cells in unison with calcium phosphate ceramic for bone regeneration |
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Anne Laure Gamlin, Meadhbh A Brennan, Audrey Renaud, Celine Charrier, Dominique Heymann, Valerie Trichet, and Pierre Layrolle |
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59 |
MFG-E8 is a novel regulator of osteoclast differentiation and function |
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Jieun Shin, Abe Toshiharu, Hosur Kavita, Udey C Mark, Chavakis Triantafyllos, and Hajishengallis George |
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60 |
Modulation of Sclerostin Expression by Estrogen via BMP-2 Signaling in Human Mesenchymal Stromal Cells and Osteoblasts |
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Soon Jung Hwang |
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61 |
Novel small molecule inhibitors of human RANKL that targe its trimerization |
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Vagelis Rinotas, Foteini Violitzi, Polyxeni Alexiou, Fotini Liepouri, Anna Maranti, Katerina Tsiliouka, Alexandros Strongilos, Thanos Papakyriakou, Christos Papaneophytou, George Kontropidis, Elias Couladouros, Elias Eliopoulos, and Eleni Douni |
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62 |
Osteogenic and osteoclastic differentiation of human mesenchymal stem cells and monocytes in a miniaturized three-dimensional culture with mineral granules |
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Anne Laure Gamblin, Audrey Renaud, Céline Charrier, Philippe Hulin, Guy Louarn, Dominique Heymann, Valérie Trichet, and Pierre Layrolle |
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63 |
Osteoimmunological analysis in transgenic mice overexpressing human RANKL |
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Maria Papadaki, Vagelis Rinotas, and Eleni Douni |
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64 |
Osteoimmunological concerns and exogenous nitrates: A discussion of invitro and invivo envirotoxicological research findings. |
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Catherine Zeman, Lisa Beltz, Alison Beharka, and Junu Shrestha |
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65 |
Pasteurella multocida Toxin requires mTOR activity for osteoclast differentiation |
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Bianca Kloos and Katharina F Kubatzky |
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66 |
Potential role of danfer-associated molecular patterns in aortic valve calcification |
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Xianzhong Meng, Lihua Ao, and David A Fullerton |
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67 |
Protein Kinase Inhibitor Y reciprocally regulates osteoblast and adipocyte differentiation by downregulating Leukemia Inhibitory Factor |
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Xin Chen, Bryan S Hausman, Guangbin Luo, Guang Zhou, Shunichi Murakami, Janet Rubin, and Edward M Greenfield |
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68 |
Quorum Sensing is required for Acinetobacter to Impair Osseointegration of Orthopaedic Implants in Mice |
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Hyonmin Choe, Ashley N Rettew, Bryan S Hausman, Sona Haku, Hani A Essber, Steve H Marshall, Ozan Akkus, Phillip N Rather, Robert A Bonomo, and Edward M Greenfield |
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69 |
RANKL+ neutrophils in the bone marrow are guided by tumor educated T cells: cooperation in the pre-metastatic niche |
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Triciana Gonçalves-silva, Ana Carolina Monteiro, Ana Carolina Mercadante, Suellen Perobelli, Wallace Mello, Alex Balduino, and Adriana Bonomo |
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70 |
Regulation of bone metabolism by Semaphorin 3A |
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Mikihito Hayashi, Tomoki Nakashima, and Hiroshi Takayanagi |
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71 |
Relaxin induces osteoblast differentiation and accelerates bone remodeling in mice |
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Carolina L Duarte Puerto, Yukiho Kobayashi, Tatsuo Kawamoto, and Keiji Moriyama |
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72 |
Role of new generation osteoporosis-preventive selective estrogen receptor modulators in B cell development and function |
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Angelina Bernardi, Annica Andersson, Louise Grahnemo, Merja Nurkkala-Karlsson, Hans Carlsten, and Ulrika Islander |
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73 |
Single nucleotide polymorphisms at the Smad3 and NFATc2 genes and their role in the Rheumatoid Arthritis |
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Agnieszka Paradowska-Gorycka, Anna Felis-Giemza, Katarzyna Romanowska-Próchnicka, Barbara Raszkiewicz, Malgorzata Mańczak, and Marzena Olesinska |
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74 |
The effectos of SRC-family kinase inhibitors on osteoclast development |
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Daniel Csete, Dávid Győri, Bálint Tél, Tibor Vántus, György Kéri, Csaba SzántaI-Kis, and Attila Mócsai |
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75 |
The interaction of traumatic brain injury and fracture healing: in vivo analysis of the posttraumatic levels of insulin and osteocalcin in a combined trauma model in mice. |
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Serafeim Tsitsilonis, Ricarda Locher, Anja Garbe, Frank Graef, Schmitt-Bleek Katharina, Christian Kleber, and Klaus-Dieter Schaser |
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76 |
The role of neutrophil-derived MRP-14 in implant-associated infection |
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Ulrike Alexandra Dapunt, Thomas Giese, Sabine Stegmaier, Volker Ewerbeck, and Gertrud Maria Hänsch |
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77 |
The tissue selective estrogen complex efficiently inhibits experimental arthritis and inflammation-induced bone loss without uterine side effects |
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Annica Andersson, Angelina Bernardi, Alexandra Stubelius, Merja Nurkkala-Karlsson, Louise Grahnemo, Hans Carlsten, and Ulrika Islander |
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78 |
Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation |
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Hyunsoo Kim, Seoung Hoon Lee, and Yongwon Choi |
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79 |
Wnt5a-Ror2 signal regulates function of osteoclasts through Daam2-Rho pathway |
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Shunsuke Uehara, Akihiro Ishihara, Kazuhiro Maeda, Teruhito Yamashita, Takashi Nakamura, Shigeaki Kato, Akira Kikuchi, Michiru Nishita, Yasuhiro Minami, Nobuyuki Udagawa, Naoyuki Takahashi, and Yasuhiro Kobayashi |
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80 |
Epigenetically regulated genes by RANKL in osteoclastogenesis |
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Haruhiko Nakamura, Tomoki Nakashima, Mikihito Hayashi, Hiroshi Takayanagi, and Sakae Tanaka |
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81 |
Conditional OSTM1 mice demonstrate cell autonomous function in osteoclast |
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Monica Pata and Jean Vacher |
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| |
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