3rd International Conference on Model Hosts

Preliminary Program

Thursday, September 17

 

 

 

6:00 PM

 

Conference Registration

 

 

 

8:00 PM

 

Welcome Reception / Dinner

 

 

 

Friday, September 18

 

 

 

7:30 AM

 

Breakfast

 

 

 

9:00 AM

 

Welcome and Opening Remarks

 

 

 

Session I

 

Modeling of microbial pathogenesis and virulence 1

Chairs: Michael Gilmore and Kimberly Kline

9:05 AM

1

Probing bacterial social behaviors during polymicrobial infection

Marvin Whiteley

9:35 AM

2

Host defense through symbiosis: Ants, agriculture, and antibiotics

Cameron Currie

10:05 AM

3

Modeling polymicrobial wound infections

Kendra Rumbaugh

10:35 AM

4

Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection

Apollo Stacy

11:05 AM

5

Modulation of cellular processes of macrophages and amoeba by the AnkB effector of Legionella pneumophila

Yousef Abu Kwaik

 

 

 

11:35 AM

 

Coffee Break

 

 

 

Session II

 

Modeling of microbial pathogenesis and virulence 2

Chairs: Marvin Whiteley and Gary Dunny

12:00 PM

6

Fungal interactions with soil phagocytic predators could facilitate mammalian virulence

Arturo Casadevall

12:30 PM

7

“Smart TnSeq” and other new tools for assessing competitive fitness and virulence of Enterococcus faecalis in model hosts.

Gary Dunny, Jennifer Dale, Aaron Barnes, Kerryl Greenwood-Quaintance, Kenneth Beckman, Robin Patel and Purna Kashyap

1:00 PM

8

Reverse Koch's postulates indicate Escherichia coli alleviates Pseudomonas aeruginosa intestinal colonisation and disease

Theodoulakis Christofi and Yiorgos Apidianakis

1:30 PM

9

In-host evolution of antibiotic resistant Enterococcus faecalis during an extended hospital outbreak

Daria Van Tyne, Abigail McGuire, Mark Huycke, Jose Saavedra, Jenna Wurster, Ashlee Earl and Michael Gilmore

 

 

 

2:00 PM

 

Lunch and Informal Discussions

 

 

 

7:30 PM

 

Dinner and Informal Discussion

 

 

 

Saturday, September 19

 

 

 

7:30 AM

 

Breakfast

 

 

 

Session III

 

The C. elegans immune response

Chairs: Danielle Garsin and Alejandro Aballay

9:00 AM

10

Organismal control of defense responses and recovery from infections in C. elegans

Alejandro Aballay

9:30 AM

11

Sesamin prolongs lifespan of Caenorhabditis elegans through regulation of genes related to caloric restriction

Yumiko Nakatani, Yukie Yaguchi, Noriko Kashima, Tomomi Komura, Eriko Kage-Nakadai, Keiji Terao and Yoshikazu Nisikawa

10:00 AM

12

Aversion response of Caenorhabditis elegans to Gram negative and Gram Positive bacteria is driven by odor and chemosensory neural circuits

Varsha Singh, Shravani Prakhya, Madhumanti Dasgupta and Anjali Gupta

10:30 AM

13

How C. elegans fights fungal infection

Nathalie Pujol

11:00 AM

14

Modeling interactions between Enterococcus faecalis and Candida albicans in C. elegans

Danielle A Garsin, Carrie E Graham, Melissa R Cruz and Michael C Lorenz

 

 

 

11:30 AM

 

Coffee Break

 

 

 

Session IV

 

The plant immune response

Chairs: Frederick Ausubel and Xinnian Dong

12:00 PM

15

Pathogen-encoded Proteases activate an immune response in plants

Frederick Ausubel and Zhenyu Cheng

12:30 PM

16

Redox rhythm reinforces the circadian clock to gate immune response

Mian Zhou, Wei Wang, Sargis Karapetyan, Musoki Mwimba, Jorge Marques, Nicolas Buchler and Xinnian Dong

1:00 PM

17

Mechanisms of pathogenesis and the evolution of virulence in Mycosphaerella fungal plant pathogens: New models for fungal host-microbe interactions?

Ioannis Stergiopoulos

1:30 PM

18

Signaling mediated by cell-wall derived damage-associated molecular patterns in Arabidopsis thaliana

Giulia De Lorenzo, Felice Cervone, Manuel Benedetti, Daniela Pontiggia, Ilaria Verrascina, Benedetta Mattei and Simone Ferrari

 

 

 

2:00 PM

 

Lunch and Informal Discussions

 

 

 

7:30 PM

 

Dinner and Informal Discussion

 

 

 

Sunday, September 20

 

 

 

7:30 AM

 

Breakfast

 

 

 

Session V

 

Yellow biotechnology 1

Chairs: Andreas Vilcinskas and Dominique Ferrandon

9:00 AM

19

Insects as models to study host-pathogen-coevolution

Andreas Vilcinskas

9:30 AM

20

Galleria mellonella – a model for infection studies, toxicity testing and drug development

Olivia Champion, Richard Titball and Sariqa Wagley

10:00 AM

21

The role of Drosophila melanogaster gut microbiota in host health and disease

Nichole Broderick

10:30 AM

22

Enterocyte purge and rapid recovery is a fast resilience reaction of the Gut Epithelium to Toxin or Xenobiotics exposure

Kwang-Zin Lee, Matthieu Lestradet, Stefanie Schirmeier, Antonin Schmitz, Caroline Spenle, Olivier Lefebvre, Céline Keime, Samuel Liegeois, Wennida Yamba, Richard Bou Aoun, Yannick Schwab, Frédéric Dalle, Patricia Simon-Assmann and Dominique Ferrandon

 

 

 

11:00 AM

 

Coffee Break

 

 

 

Session VI

 

Yellow biotechnology 2

Chairs: Nichole Broderick and Yiorgos Apidianakis

11:30 AM

23

High baseline of intestinal stem cell mitosis associates with extreme regenerative inflammatory signaling and tumorigenesis in Drosophila

Yiorgos Apidianakis, Chrysoula Pitsouli, Myrofora Panagi, Vasileia Tamamouna, Antria Theophanous, Maria Demosthenous, Maria Michail and Markella Papadopoulou

12:00 PM

24

Cell culture of Drosophila melanogaster as an experimental model for studying of recombination in Wolbachia pipientis

Irina Goryacheva, Boris Andrianov, Tatiana Gorelova and Ilia Zakharov

 

 

 

12:30 PM

 

Lunch and Informal Discussions

 

 

 

3:30 PM

 

City Tour

 

 

 

7:30 PM

 

Dinner and Informal Discussion

 

 

 

Monday, September 21

 

 

 

7:30 AM

 

Breakfast

 

 

 

Session VII

 

Hosts, models, and resistance in guiding drug discovery

Chairs: Nathalie Pujol and Elisa Borghi

9:00 AM

25

Characterizing novel small molecule inhibitors of M tuberculosis

Samantha Wellington, Partha Nag, Raymond  Nietupski, Michael  Fitzgerald, Stewart  Fisher, Stuart Schreiber and Deborah Hung

9:30 AM

26

Potential effects of Acetylcholine in the pathogenesis, biofilm formation and outcome of Candida Albicans experimental infections

Monica Falleni, Ranjith Rajendran, Delfina Tosi, Federica Perdoni, Giulia Morace, Gordon Ramage, Christopher Nile and Elisa Borghi

10:00 AM

27

Virulence strategies of Enterococcus faecalis

Kimberly Kline

 

 

 

10:30 AM

 

Coffee Break

 

 

 

Session VIII

Mammals and model hosts: from evolution to the lines of juxtaposition

Chairs: Arturo Casadevall and Daniel Kalman

11:00 AM

28

A multi-host approach for the systematic analysis of virulence factors of 1201 signature-tagged deletion mutants of Cryptococcus neoformans

A Desalermos, X Tan, R Rajamuthiah, M Arvanitis, Y Wang, D Li , TK Kourkoumpetis, BB Fuchs and Elefterios Mylonakis

11:30 AM

29

A family of commensal-derived molecules regulates damage tolerance in worms flies and mammals

Daniel Kalman, Robert  Sonowal and Alyson Swimm

12:00 PM

30

Use of the wax moth, Galleria mellonella, as a model to investigate the co-evolutionary arms race between insects and microbial pathogens. 

Ivan Dubovskiy, Vadim Kryukov, Ekaterina Grizanova, Miranda Whitten, Krishnendu Mukherjee, Andreas Vilcinskas, Viktor Glupov and Tariq Butt

12:30 PM

31

Chemokine-dependent protection against systemic candidiasis: from the bench to the bedside

Michail Lionakis

1:00 PM

32

Screening in Planarians identifies MORN2 as a key component in LC3-associated Phagocytosis and resistance to bacterial infection

Eric Ghigo

 

 

 

1:30 PM

 

Closing Remarks

 

 

 

1:40 PM

 

Lunch and Informal Discussions

 

 

 

8:00 PM

 

Farewell Dinner

 

 

 

Tuesday, September 22

 

 

 

7:30 AM

 

Breakfast

 

 

 

9:00 AM

 

Departure