12th International Conference on Innate Immunity

Program

Friday, June 19

 

 

 

6:00 PM

 

Conference Registration

 

 

 

8:00 PM

 

Welcome Reception/Dinner

 

Saturday, June 20

 

 

 

8:00 AM

 

Breakfast

 

 

 

8:45 AM

 

Welcome and Opening Remarks

 

 

 

Session 1

 

Innate immune cells

Chairs: Mantovani and Chavakis

9:00 AM

1

Functional diversity of macrophage/monocyte subsets

Shizuo Akira

9:25 AM

2

Chromatin remodeling and autocrine TNFα control interleukin-6 expression in human neutrophils

Marco Cassatella, Maili Zimmermann and Nicola Tamassia

9:50 AM

3

Ribonucleoprotein assemblies as determinants of macrophage activation states

Yiota Kafasla, Orzalia Hazapis, Antonis Skliris, Margarita Chatzimike, Eleni Christodoulou-Vafeiadou, Niki Lourou and Dimitris Kontoyiannis

10:15 AM

4

The Interleukin-13 Receptor-alpha 1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4

Raymond Donnelly, Faruk Sheikh, Harold Dickensheets, Thirumalai Ramalingam, Laura Helming and Siamon Gordon

10:30 AM

5

Role of Lactosylceramide-enriched lipid rafts in innate immune response of human phagocytes

Kazuhisa Iwabuchi and Hitoshi Nakayama

10:45 AM

6

Sphingolipids regulate the activation of dendritic cells upon virus infections or TLR stimulation

Young-Jin Seo, Curtis Pritzl and Bumsuk Hahm

 

 

 

11:00 AM

 

Coffee break and poster viewing

 

 

 

Session 2

 

Host-microbe interactions

Chairs: Murray and Van Dyke

12:00 PM

7

Metabolic control of innate and adaptive immunity against Tuberculosis

Giuseppe Matarese

12:25 PM

8

Cellular energy metabolism and regulation of immune responses to severe infections

Mihai Netea

12:50 PM

9

TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages

Bjarte Bergstrøm, Marie Aune, Jane Awuh, June Kojen, Liv Ryan, Trude Flo, Tom Mollnes, Jørgen Stenvik and Terje Espevik

1:15 PM

10

The Gal-lectin adhesin of Entamoeba histolytica binds macrophage and activates the inflammasome as a pathogenicity sensor for invasive ameba

Leanne Mortimer, France Moreau and Kris Chadee

1:30 PM

11

Efferocytosis promotes the escape of intracellular Staphylococcus aureus from macrophages leading to dissemination of infection

Joanna Koziel, Danuta Bryzek, Magdalena Widziolek, Izabela Glowczyk, Katarzyna Maresz, Agnieszka Maciag-Gudowska and Jan Potempa

1:45 PM

12

NIH Innate Immune Funding Opportunities

Thomas Palker

 

 

 

2:10 PM

 

Lunch/Informal Discussions

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

 

Sunday, June 21

 

 

 

8:00 AM

 

Breakfast

 

 

 

Session 3

 

Regulation of innate immunity

Chairs: Akira & Cassatella

9:00 AM

13

Dynamic Programming of Innate Leukocytes

Liwu Li

9:25 AM

14

DEL-1: A homeostatic regulator of leucocyte function Triantafyllos Chavakis, Ioannis Mitroulis, Rashim Pal Singh, Lan-Sun Chen, Eun Young Choi, Jong-Hyung Lim, Jindra Chmelar, Kyoung-Jin Chung, Ben Wielockx and George Hajishengallis

9:50 AM

15

PTX3 in the interplay between the cellular and the humoral arm of innate immunity Alberto Mantovani

10:15 AM

16

Self extracellular RNA as new alarm signal and inflammatory factor in cardiovascular diseases

Klaus Preissner, Hector Cabrera-Fuentes and Silvia Fischer

10:40 AM

17

Lessons learned from gain- and loss-of-function mutations in complement C3: functional hot spots, disease triggers and therapeutic consequences.

Daniel Ricklin, Georgia Sfyroera, Edimara Reis, Hui Chen, Emilia Wu, Yiannis Kaznessis, Kristina Nilsson-Ekdahl, Bo Nilsson and John Lambris

11:05 AM

18

Interleukin-3 induces emergency myelopoiesis and is a potential therapeutic target in sepsis

Georg Weber, Benjamin Chousterman, Shun He, Ashley Fenn, Manfred Nairz, Atsushi Anzai, Thorsten Brenner, Florian Uhle, Yoshiko Iwamoto, Clinton Robbins, Lorette Noiret, Sarah Maier, Tina Zönnchen, Nuh Rahbari, Sebastian Schölch, Anne Klotzsche-von Ameln, Triantafyllos Chavakis, Jürgen Weitz, Stefan Hofer, Markus Weigand, Matthias Nahrendorf, Ralph Weissleder and Filip Swirski

 

 

 

11:20 AM

 

Coffee break and poster viewing

 

 

 

Session 4

 

Immunomodulation and therapeutic intervention

Chairs: Dempsey & Ricklin

12:00 PM

19

Compstatin Cp40: an immune modulator on a journey from disease models to clinical development

John Lambris, Alexandra Primikyri, Sophia Koutsogiannaki, Yiannis Sarigiannis, Malvina Papanastasiou, Sotirios Koutsopoulos, Jihyoun Seong, Hongbin Wang, Chen Gang, Markus Huber-Lang, Martijn van Griensven, Bo Nilsson, Kristina Nilsson-Ekdahl, Alireza Biglarnia, Richard Smith, George Hajishengallis, Despina Yancopoulou, Antonio Risitano and Daniel Ricklin

12:25 PM

20

Targeted intervention approaches to treat inflammatory bone loss

George Hajishengallis, Tomoki Maekawa, Toshiharu Abe, Evlambia Hajishengallis, Kavita Hosur, Triantafyllos Chavakis and John Lambris

12:50 PM

21

Combinatorial Targeting of TSLP, IL-25, and IL-33 in Type 2 Cytokine-driven Inflammation and Fibrosis

Thomas Wynn

1:15 PM

22

Microtubule Disruption Synergizes with Oncolytic Virotherapy by Inhibiting Interferon Translation and Potentiating Bystander Killing

Jean-Simon Diallo

1:30 PM

23

DNA Nanotubes as Intracellular Delivery Vehicles in vivo

Sabine Sellner, Samet Kocabey, Tim Liedl and Markus Rehberg

1:45 PM

24

Commercialization - TBA

Charles Baltic

 

 

 

2:10 PM

 

Lunch/Informal Discussions

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

 

Monday, June 22

 

 

 

8:00 AM

 

Breakfast

Session 5

 

Mechanisms of Inflammation

Chairs: Caligiuri & Akassaglou

9:00 AM

25

Neutrophil-Vessel wall interactions in vivo: Mode, Mechanisms and Pathogens

Sussan Nourshargh

9:25 AM

26

E-selectin-triggered release of MRP8/14 induces TLR-4 dependent beta 2 integrin activation during neutrophil recruitment in vivo

Markus Sperandio

9:50 AM

27

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

Constantinos Mikelis and Silvio Gutkind

10:15 AM

28

Systems Elucidation of Novel Signaling and Epigenetic Mechanisms for Inflammation Control

Xian Chen, Ling Xie, Cui Liu and Li Wang

10:40 AM

29

Matricellular protein CYR61/CCN1 paves the way for the recruitment of monocytes and neutrophils to the site of inflammation

Yalin Emre and Beat Imhof

10:55 AM

30

Scavenger protein CD5L acts as a pro-oncogenic factor in hepatocytes

Gemma Aran, Lucía Sanjurjo, Marina Simon, Isabel Ojanguren, Margarita Sala, Ramon Planas, Carolina Armengol and Maria-Rosa Sarrias

 

 

 

11:10 AM

 

Coffee break and poster viewing

 

 

 

Session 6

 

Inflammation and Disease

Chairs: Sperandio and Nourshargh

12:00 PM

31

Liver cancer, at the crossroads of diet, genetics, metabolism and inflammation

Jesse Riordan and Joseph Nadeau

12:25 PM

32

How and Why the Heart is a Target for Dysfunction after Polymicrobial Sepsis

Peter Ward, Fatemeh Fattahi, Markus Bosmann, Jose Jalife and Hector Valdivia

12:50 PM

33

Regeneration of the adult zebrafish brain: an essential, positive role for inflammation

Michael Brand

1:15 PM

34

Resolution of Inflammation, Periodontitis and Cardiovascular Disease

Thomas Van Dyke, Alpdogan Kantarci, Hatice Hasturk and James Hamilton

1:40 PM

35

Combined inhibition of complement and CD14 improved survival in porcine polymicrobial sepsis

Espen Skjeflo, Caroline Sagatun, Knut Dybwik, Sturla Aam, Sven Urving, Miles Nunn, Hilde Fure, Corinna Lau, Ole-Lars Brekke, Terje Espevik, Andreas Barratt-Due, Erik Nielsen and Tom Mollnes

 

 

 

1:55 PM

 

Lunch/Informal Discussions

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

 

Tuesday, June 23

 

 

 

8:00 AM

 

Breakfast

 

 

 

Session 7

 

Regulatory interactions in the immune system

Chairs: Ward & Netea

9:00 AM

36

Control points in innate and adaptive immunity mediated by amino acid metabolism

Peter Murray

9:25 AM

37

Blood in the Brain: Vascular mechanisms linking innate and adaptive immunity

Katerina Akassoglou

9:50 AM

38

Synergy in the chemokine system: a new model for tuning chemokine activities

Mariagrazia Uguccioni

10:15 AM

39

The steroid hormone DHEA limits inflammatory cell recruitment via regulating endothelial Del-1 expression

Athanasios Ziogas, Vasileia Alexaki, Tomoki Maekawa, Johannes Wiessner , Achilleas Gravanis , Markus Sperandio, George Hajishengallis and Triantafyllos Chavakis

10:30 AM

40

Gigingipains, proteases from Porphyromonas gingivalis effectively triggers NETs with compromised bactericidal activity

Danuta Bryzek, Izabela Glowczyk, Jan Potempa and Joanna Koziel

10:45 AM

41

NLRP3 recognizes Helicobacter pylori CagA protein to induce IL-1beta response

Akinori Takaoka

 

 

 

11:00 AM

 

Coffee break and poster viewing

 

 

 

Session 8

 

NK Cells

Chairs: Wynn & Mollnes

 

 

 

12:00 PM

42

Biology and clinical applications of human NK cells

Lorenzo Moretta, Daniela Pende, Mariella Della Chiesa, Maria Cristina Mingari, Alessandro Moretta and Franco Locatelli

12:25 PM

43

TBA

Michael Caliguiri

12:50 PM

44

Regulation of Natural Cytotoxicity Receptor expression on NK cells

Andrea De Maria, Federica Bozzano and Francesco Marras

1:15 PM

45

TBA

Antal Rot

1:40 PM

46

Inflammation and Metabolism Nexus in Macrophage Biology

Shankar Subramaniam

2:05 PM

47

Aicardi Goutières syndrome: Lupus-like autoimmune disease caused by inappropriate intracellular nucleic acid sensing.

Björn Hiller, Katrin Peschke, Tina Schuman, Martin Kleefisch, Alexander Hennig, Rayk Behrendt and Axel Roers

 

 

 

2:25 PM

 

Closing Remarks

 

 

 

2:30 PM

 

Lunch/Informal Discussions

 

 

 

8:00 PM

 

Farewell Dinner

 

Wednesday, June 24

 

 

 

8:00 AM

 

Breakfast

 

 

 

 

 

Departure

 

 

POSTERS

48

A common genetic variant is associated with altered major histocompatability complex classII expression and pyrehroid pesticide exposure in Parkinson’s desease George Kannarkat, Darcie Cook, Jae-Kyung Lee, Jianjun Chang, Jaegwon Chung, Elizabeth Sandy, Kimberly Paul, Beate Ritz, Jeff Bronstein, Stewart Factor, Jeremy Boss and Malu Tansey

49

A Novel Cyclic Helix B Peptide Inhibits Dendritic Cell Maturation during the Amelioration of Acute Kidney Graft Rejection through Jak-2/STAT3/SOCS1

Cheng Yang

50

A Novel Opsonin Facilitating the Phagocytic-mediated Killing of Staphylococcus aureus

Mutaib Mashraqi and Prof Wilhelm Schwaeble

51

A novel role of alpha-synuclein as a proinflammatory factor in DSS colitis model.

Athanasia Apostolou, Panagiotis Giannogonas, Kostas Vekrellis and Katia Karalis

52

A population of natural killer (NK) cells with increased antibody-dependent cellular cytotoxic (ADCC) activity and lacking the signaling protein FcRγ is expanded in HIV-infected individuals.

Jingling Zhou, Marit Kramski, Anna Hearps, Fathiah Amran, Tom Angelovich, Esther Leong, Patricia Price and Anthony Jaworowski

53

Alteration of cytocine pattern of lipopolysacharide-stimulated peripheral blood mononuclear cells from patients with total hip arthroplasty with mild and severe periprostheric osteolysis

Zuzana Čapková, Tereza Dýšková, Petra Schneiderová, Regina Fillerová, Jiří Gallo and Eva Kriegová

54

An Essential Role for Interferon-beta_x0002_ in the Induction of Interferon-Stimulated Gene (ISG) Expression by Lipopolysaccharide in Macrophages

Raymond Donnelly, Faruk Sheikh, Harold Dickensheets, Ana Gamero and Stefanie Vogel

55

Antibody-dependent NK Cell Activation by Non-Neutralizing Immune Sera to Dengue Virus

Peifang Sun, Charmagne Beckett, Zhaodong Liang, Kevin Porter and Maya Williams

56

Antimicrobial peptides as effector molecules of innate immune system

Tatiana Ovchinnikova, Sergey Balandin, Ilia Bolosov and Pavel Panteleev

57

BH3 interacting-domain death agonist dependent apoptosis and toll-like receptor 7-stimulated tumor necrosis factor α cause extramedullary hematopoiesis in systemic lupus erythematosus (SLE)

Haoyang Zhuang, Shuhong Han, Yuan Xu and Westley Reeves

58

Binding of CXCL8 / IL-8 by Mycobacterium tuberculosis – an identification of the tubercule bacilli putative “IL-8 receptor”

Bozena Dziadek, Anna Brzostek, Marcin Grzybowski, Marek Fol, Agnieszka Krupa, Jakub Kryczka, Anna Kurdowska and Jaroslaw Dziadek

59

Binding of oxLDL to CD69 induces regulatory responses and ameliorates atherosclerosis

Katerina Tsilingiri, Hortensia De la Fuente, Pilar Martín and Francisco Sánchez Madrid

60

Cellular crosstalk between the complement and coagulation system in polytrauma patients

Rebecca Wiegner, Felix Hoenes, Miriam Kalbitz, Manfred Weiss, Florian Gebhard, Markus Huber-Lang and Stephanie Denk

61

Central role of complement in sepsis-induced Neutrophil dysfunction

Stephanie Denk, Rebecca Wiegner, Miriam Neher, Manfred Weiss and Markus Huber-Lang

62

Competitive Binding of WRKY Proteins to a Conserved Double W-box in the CaWRKY40 Promoter Regulates Its Synergistic Response to Pathogen and Heat

Zhiqin liu, sheng yang, lanping shi and shuilin he

63

Could Prolactin assume a supporting role to conventional drug treatment during the acute phase of Chagas’ disease?

Marina Filipin, Cássia Da Costa, Fabricia Santello, Vânia Brazão, Miriam Alonso Toldo and José Do Prado Júnior

64

Developmental endothelial locus-1 attenuates lung fibrosis via regulation of TGF-beta activation

Dong-Young Kim, Seung-Hwan Lee and Eun Choi

65

Different expression pattern regulation of activating and inhibitory NK cell receptors results in aGVHD prevention in cd69-/- mice

Katerina Tsilingiri, Raquel Sánchez-Díaz, Sandra Lasarte, Marta Relaño and Pilar Martín

66

Dimorphism of KIR3DL1 Allotype Recognition of HLA based on Bw4 Motif Subtype.

Phillip Pymm, Philippa Saunders, Geraldine O’Connor, Julian Vivian, Daniel McVicar, Andrew Brooks and Jamie Rossjohn

67

Dissection of Zigzag Evolution between Phytophthora capsici Pathopoiesis and Capsicum annuum Immunity Mediated by CAP1A, CAP2A, CaSRC2 and CaSGT1

Zhiqin liu and shuilin he

68

Does zinc supplementation during Trypanosoma cruzi infection exerts an enhancing action on the innate immune response in pregnant Wistar rats?

Cássia Bronzon da Costa, Marina Filipin, Fabricia Santello, Vânia Brazão, Miriam Alonso Toldo, José Do Prado Júnior and Ana Amélia Abrahão

69

Effects of Toll-Like Receptor Ligands on Phagocytosis of Candida albicans by RAW 264.7 Macrophages

Lynette Sigola, Ana-Lucia Fuentes, Len Millis, Jacqueline Vapenik and Armstrong Murira

70

Evaluation of different conjugations for P0 antigen in bovines against a Brazilian Rhipicephalus microplus (Acari:Ixodidae) tick strain.

Pedro Encinosa Guzmán, Gervasio Bechara, Gustavo Sanches, Patricia Evora, Breno Cruz, Gilson Oliveira, Alvimar da Costa, Mario Estrada, Eulogio Vásquez and Alina Rodriguez

71

Evaluation of Different Bacteria phagocytosis by RAW 264.7 Macrophages

Nur Balci, Adile Salehli, Esat Bugrahan Toksoz, Metin Cetin, Sevda Er

72

Grouper voltage dependent anion selective channel protein 2 affects NNV infection through ATP transportation and apoptosis of mitochondria

Jui-Shin Chang and Shau-Chi Chi

73

HIV-1 Nef and HCV Core hijack TRAF signaling in macrophages.

Wasim Abbas, Amit Kumar and Georges Herbein

74

IFNɑ engages a sustained antiviral response depending on STAT2/IRF9 but not ISGF3

Katarzyna Blaszczyk, Hanna Nowicka, Joanna Wesoly and Hans Bluyssen

75

Implication of combined PD-L1/PD-1 signaling blockade with Cytokine-induced killer cells as a synergistic immunotherapy for metastatic unresectable cancers

Congqi Dai and Jin Li

76

Innate Immunity and Atherosclerosis

Alexander Orekhov

77

Innate immunity is critical for the initiation of protective immunity in rabies

Zhen Fu

78

Innate microenvironment at site of infection is crucial for generation of memory T cells

RAJESH PARMAR, VISHAKHA BHURANI, HARDIK PATEL, ADITI MATHUR, NAVEEN YADAV and SARAT DALAI

79

MMP-9 regulates expression of sTREM-1 during secondary bacterial pneumonia

Gudrun Weiss, Cheryl Lai, Robert Snelgrove, Clare Lloyd and Tracy Hussell

80

Molecular cloning of atlantic salmon (S. salar) and trucha arcoiris (O. mykiss), toll-like receptors and expression analysis in vitro during Piscirikettsia salmonis infection

Jaime Figueroa, Adolfo Isla and Denise Haussmann

81

Morphological changes induced by P0 peptide in oocytes of Rhipicephalus sanguineus Brazilian strain ticks fed on vaccinated dogs

Gustavo Sanches, Alina Mallon, Patricia Evora, Mario Estrada and Gervasio Bechara

82

Muted neutrophil response to acute SIV infection is associated with altered mucosal immunity

Tiffany Hensley-McBain, Laura Richert-Spuhler, Thomas Vanderford, Jacob Estes, Brandon Keele, Brian Johnson and Nichole Klatt

83

NK cell activation and dysfunction, but not T cell or monocyte activation, persist for at least 12 months in HIV+ individuals following combination antiretroviral therapy.

Anna Hearps, Jingling Zhou, Michelle GIles, Julian Elliott, Fathiah Amran, Patricia Price and Anthony Jaworowski

84

NK cell biomarkers are associated with time to castration resistance and overall survival in patients with metastases at prostate cancer diagnosis

christine pasero, gwenaelle gravis, samuel granjeaud, mathilde guerin, jeanne thomassin, palma rocchi, jochen walz, naji salem and daniel olive

85

Oxidative stress decreases interferon-induced antiviral responses.

Mohammed Selman, Paula Ou and Jean-Simon Diallo

86

BTN3A molecules improve Vγ9Vδ2T cells-based immunotherapy in Acute Myeloid Leukemia

audrey benyamine, aude leroy, julie gertner-dardenne, celine castanier, emilie mamessier, remy castellano, yves collette, norbert vey and daniel olive

87

Phenotype of innate immune cells in the brain after neonatal hypoxia-ischemia

Carina Mallard, Nina Erkenstam, Pete Smith, Henrik Hagberg and Karin Sävman

88

Phenotype, activation and expansion patterns of circulating NK cells in response to H. Pylori antigens

Karolina Rudnicka, Anthony Moran and Magdalena Chmiela

89

Reconstructing the TIR side of the Myddosome

Laurens Vyncke, Celia Bovijn, Ewald Pauwels, Tim Van Acker, Elien Ruyssinck, Jan Tavernier and Frank Peelman

90

Regnase-1 as a regulator of the hyposensitivity in the epithelium.

Ewelina Dobosz, Beata Bugara, Jolanta Jura, Jan Potempa and Joanna Koziel

91

Relationship between innate immunity, inflammatory soluble markers and metabolic-clinical parameters in ART treated HIV positive patients with undetectable viral load

Chiara Dentone, Daniela Fenoglio, Alessio Signori, Giovanni Cenderello, Alessia Parodi, Federica Bozzano, Michele Guerra, Pasqualina De Leo, Valentina Bartolacci, Eugenio Mantia, Milena Zoppi, Giancarlo Orofino, Francesca Kalli, Francesco Marras, Paolo Fraccaro, Mauro Giacomini, Giovanni Cassola, Bianca Bruzzone, Giuseppe Ferrea, Claudio Viscoli, Gilberto Filaci, Andrea De Maria and Antonio Di Biagio

92

Role of chicken innate immunity in vaccine-induced protection against Marek’s disease virus

Mohammad Heidari

93

Role of galectin-1 in Neospora caninum invasion/infection models

Isabel Cristina Vigato Ferreira, Luiz Pereira, Cássia Da Costa, Maraísa Verri and Ana Yatsuda Natsui

94

Role of mycobacterial proteins binding CXCL-8 / IL-8 in modulating innate immune response to infection with Mycobacterium tuberculosis

Agnieszka Krupa, Marek Fol, Bozena Dziadek, Anna Kurdowska and Jaroslaw Dziadek

95

Role of Toll-like receptor 4 in emotional responses and the dopamine system.

Teresa Femenia, Tim Arentsen, Qian Yu, Hans Forssberg and Rochellys Diaz Heijzt

96

S100A proteins, koebnerisin and psoriasin - novel mediator of systemic inflammation in psoriasis?

Aleksandra Batycka-Baran, Eva Hattinger Hattinger, Burkhard Summer Summer, OM Zack Howard Howard, Jörg Prinz and Ronald Wolf

97

Self extracellular RNA as new alarm signal in innate immunity and as an inflammatory factor in cardiovascular diseases and vascular remodeling

Klaus Preissner, Hector Cabrera-Fuentes, Silvia Fischer and Elisabeth Deindl

98

The Effects of a Viral Infection in The Immune Innate Response in Salmo salar with IPNv and the effect of Prolactin as immune stimulant

Denise Haussmann, Teresa Cardenas, Felipe Cardenas, Morales Paulina, Lorenza Soto, Alejandro Yañez and Jaime Figueroa

99

The epidermal danger-signal psoriasin regulates NALP-1 inflammasome activity and IL-1β release in autoinflammatory psoriasis

Stephanie Zwicker, Eva Hattinger, Daniela Bureik, Aleksandra Batycka-Baran, Andreas Schmidt, Simon Rothenfusser, Michel Gilliet, Thomas Ruzicka and Ronald Wolf

100

The immune response in the brain of groupers after immunization with inactivated betanodavirus and following viral infection

Yuan-Kai Cheng and Shau-Chi Chi

101

The mechanism of Mx protein for eliminating betanodavirus RNA-dependent RNA polymerase

Yu-Chi Wu, Li-Chung Hsu and Shau-Chi Chi

102

The production of interleukin (IL)-1β and tumor necrosis factor (TNF)-α cause neuronal death in betanodavirus infection

Yu-Hui Chiang and Shau-Chi Chi

103

The role of host soluble inflammatory mediators induced by the  BCG vaccine for the initiation of in vitro monocyte apoptosis and T-cell profile in healthy Brazilian volunteers

Carlos Ponte, Jéssica Lima, Mariana Siqueira, Thaíze Pedro, Leandro Peres, Suellen Marinho, Paula De-Luca, Cynthia Cascabulho, Luiz Castello-Branco and Paulo Antas

104

The role of the D0 domain; the structure of the atypical Killer Cell Immunoglobulin-like Receptor, KIR2DL4

Shoeib Moradi, Richard Berry, Phillip Pymm, Andrew Brooks, Jamie Rossjohn and Julian Vivian

105

The role of the oxygen sensor PHD2 in innate immune cells during rheumatoid arthritis in mice

Kristin Franke, Sundary Sormendi, Rashim Singh, Triantafyllos Chavakis and Ben Wielockx

106

The role of the transcription factor Ror-alpha in macrophage function

Rachel Bermingham, Emily Hams and Padraic Fallon

107

The synergistic effects of iNOS and arginase gene expression in the rodent macrophage are linked to resistance against intracellular pathogens

Zhao-Rong Lun

108

TRIM33 deficiency in myeloid cells impairs resolution of inflammation in colitis model

Vanessa Petit, Aude Parcelier, Vilma Barroca, Federica Ferri, Gault Nathalie, Daniel Lewandowski and Paul-henri Romeo

109

Type 1 innate lymphoid cells contribute to the pathogenesis of chronic hepatitis B

Zhiqiang Tian, Yuzhang Wu and Bing Ni

110

UVB-triggered IL-1 beta activation is attenuated by the innate antimicrobial peptide koebnerisin in skin keratinocytes

Stephanie Zwicker, Eva Hattinger, Daniela Bureik, Thomas Ruzicka and Ronald Wolf

111

Zinc therapy: Antigens presenting cells and apoptosis profiles in pregnant rats during Trypanosoma cruzi infection

Cássia Mariana Da Costa, Marina Filipin, Fabricia Santello, Vânia Brazão, Inara Fernanda Gallo, José Do Prado Júnior and Ana Amélia Abrahão