4th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets

Program

 

Sunday, June 5

 

 

 

 

 

 

 

6:00 PM

 

Conference Registration

 

 

 

 

 

8:00 PM

 

Welcome Reception/Dinner

 

 

 

 

 

Monday, June 6

 

 

 

 

 

 

 

7:30 AM

 

Breakfast

 

 

 

 

 

 

 

8:30 AM

 

Welcome and Opening Remarks

 

 

 

 

 

 

 

Session I

 

Tumor Immunology and Immunotherapy I: Basic mechanisms & preclinical research

Chair: Costas Koumenis

 

 

8:35 AM

1

Reprogramming the immunologic microenvironment through radiation and axl targeting

Todd A Aguilera, Marjan R Rafat, Laura Castellini, Mihalis S Kariolis, Rie von Ebyen, Edward E Graves, and Amato J Giaccia

 

 

9:00 AM

2

Antiviral signaling regulates response to conventional cancer therapy and immune checkpoint blockade

Andy Minn

 

 

9:25 AM

3

Alternative splicing as a mechanism of resistance to immunotherapy

Andrei Thomas-Tikhonenko

 

 

9:50 AM

4

Mechanisms of immunosuppression within the tumor microenvironment

Serge Fuchs

 

 

 

 

 

 

 

10:15 AM

 

Coffee Break/Poster Viewing

 

 

 

 

 

 

 

Session II

 

Tumor Immunology and Immunotherapy II: Clinical research and practice

Chair: Amato Giaccia

 

 

10:50 AM

5

Ablative radiation therapy and immune checkpoint inhibition:  Where do we go from here?

Stephen Hahn

 

 

11:15 AM

6

RADVAXTM: A stratified phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic cancers

Amit Maity

 

 

11:40 AM

7

Radiation and Immune Modulation: Where are we now and what's next?

Ramesh Rengan

 

 

12:05 PM

8

Precision medicine in oncology: The MD Anderson Cancer Center Initiative

Apostolia-Maria Tsimberidou

 

 

Session III

 

Imaging of the tumor and its microenvironment

Chair: Michael Hay

 

 

 

 

 

 

 

12:30 PM

9

Deep tissue optoacoustic assessment of tumor microenvironment

Vasilis Ntziachristos

 

 

12:55 PM

10

Imaging the tumour microenvironment using clinically applicable approaches: pros and cons

Michael Horsman, Ane Iversen, and Morten Busk

 

 

1:20 PM

11

A novel PARP inhibitor PET tracer for ovarian carcinoma

Lilie Lin

 

 

1:45 PM

12

Multimodality imaging of tumour vasculature and the effects of therapy

Sean Johnson, Ollie Ogunlade, Paul Beard, Mark Lythgoe, Simon Walker-Samuel, and Barbara R Pedley

 

 

1:55 PM

13

Tumor microenvironment modulates the anticancer benefits of esomeprazole

Silvana Papagerakis, Eleftheria Mavridou, Ngya Nguyen, Li Zhengl, and Petros Papagerakis

 

 

 

 

 

 

 

2:10 PM

 

Lunch/Informal Discussions

 

 

 

 

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

Buses depart from the hotel lobby at 7:30 PM

 

 

 

 

 

 

 

Tuesday, June 7

 

 

 

 

 

 

 

7:30 AM

 

Breakfast

 

 

 

 

 

 

 

Session IV

 

Tumor hypoxia I: effects on gene expression, cell fate

Chair: Ester Hammond

 

 

8:30 AM

14

Assessment of tumor hypoxia: Facts and fallacies

Peter Vaupel and Arnulf Mayer

 

 

8:55 AM

15

Hypoxia-induced replication stress: causes and consequences

Ester M Hammond

 

 

9:20 AM

16

Phosphorylation-dependent interactions mediate distinct nuclear and cytoplasmic/non-transcriptional functions of hypoxia-inducible factor-1α

Ilias Mylonis, Maria Kourti, and George Simos

 

 

9:45 AM

17

Hypoxia-regulated non-coding RNA species

Kevin Bennewith

 

 

10:10 AM

18

HIF-dependent repression of CPT1A drives the clear-cell phenotype of clear cell renal cell cCarcinoma

Scott Welford, Weinan Du, Charles Hoppel, Laura Herrero, and Dolors Serra

 

 

10:35 AM

19

Tumor cell fate regulation by the hypoxic tumor Microenvironment

Qun Lin, Hoon Kim, and Zhong Yun

 

 

10:45 AM

20

WSB-1 regulates the metastatic potential of ER- and PR-negative breast cancer

Flore-Anne Poujade, Lisa Eigleman, Aarren Mannion, Andrew Theodosi, Christopher Cawthorne, and Isabel Pires

 

 

 

 

 

 

 

10:55 AM

 

Coffee Break/Poster Viewing

 

 

 

 

 

 

 

Session V

 

Tumor hypoxia II: impact on tumor metabolism & tumor targeting

Chair: Barbara Pedley

 

 

11:30 AM

21

Heterogenic hypoxia induced populations defined by CAIX expression display metabolic symbiosis

Adrian Harris, Kate Feldinger, Ioanna  Ledaki, and Simon Wigfield

 

 

11:55 AM

22

Regulation of intermediate metabolism by the tumor microenvironment

Tereza Golias, Ioanna Papandreou, Megan Miller, Wendi  O’Neill, Ramon Sun, and Nicholas Denko

 

 

12:20 PM

23

Fumarate hydratase (FH)-dependent metabolic adaptation to hypoxia

Marianne Koritzinsky

 

 

12:45 PM

24

Lipid droplet proteins can modulate cellular metabolism and malignant progression

Ioanna Papandreou

 

 

1:10 PM

25

Dual targeting of hypoxia and low extracellular pH in the tumour microenvironment

Michael Hay, Hong Shin, Way-Wua Wong, Benjamin Dickson, Kevin Hicks, and William Wilson

 

 

1:35 PM

26

Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling

Jing Chen

 

 

2:00 PM

27

Hypoxia and glucose/energy depletion: regulators of the tumour vascular disrupting actions of combretastatin A-4 phosphate

Chryso Kanthou, Toby Holmes, Andrew Brown, and Gillian Tozer

 

 

 

 

 

 

 

2:10 PM

 

Lunch/Informal Discussions

 

 

 

 

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

Buses depart from the hotel lobby at 7:30 PM

 

 

 

 

 

 

 

Wednesday, June 8

 

 

 

 

 

 

 

7:30 AM

 

Breakfast

 

 

 

Session VI

 

Tumor-Stroma interactions and impact on angiogenesis/vasculogenesis

Chair: Zhong Yun

 

 

8:30 AM

28

Heterogeneity of tumor stroma: Implications for stroma-targeted therapies

Ellen Puré

 

 

8:55 AM

29

The biology and function of exosomes

Raghu Kalluri

 

 

9:20 AM

30

Intertwined Functional Regulation of Angiogenesis, Invasion and Immunity in Cancer

Gabriele Bergers

 

 

9:45 AM

31

MET/AXL upregulation as a mechanism of resistance to antiangiogenic therapy

Eric Jonash

 

 

10:10 AM

32

The role of endothelial-derived Thrombospondin-1 in tumor growth and chemotherapeutic resistance

Dong Ha Bhang, Joo-Hyeon Lee, Bang-Jin Kim, Kwan-Hyuck Baek, Keri Schadler, Carla Kim, and Sandra Ryeom

 

 

10:35 AM

33

Transformation of tumor endothelial cells to mesenchymal stem cell-like cells

Menggui Huang and Yi Fan

 

 

11:00 AM

34

Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment

Hongyu Tian

 

 

 

 

 

 

 

11:10 AM

 

Coffee Break/Poster Viewing

 

 

 

 

 

 

 

Session VII

 

Stress resistance & cancer I: Targeting organelle-specific stress responses

Chair: Bradly Wouters

 

 

11:50 AM

35

Autophagy Prevents Fatal Nucleotide Pool Depletion in Ras-driven Cancer Cells

Eileen White

 

 

12:15 PM

36

Targeting the lysosome in cancer

Ravi Amaravadi

 

 

12:40 PM

37

Ubiquitin ligases in melanoma development and resistance to therapy

Hyungsoo Kim, Yan Li, Ali Khateb, Yongmei Feng, and Ze’ev Ronai

 

 

1:05 PM

38

Golgi stress and secretory stress signaling

Jan Reiling

 

 

1:30 PM

39

Downregulation of carbonic anhydrase IX impairs ECM degradation and affects actin regulatory proteins during invadopodia formation

Michaela Debreova, Lucia Csaderova, Olga Sedlakova, Silvia Pastorekova, and Eliska Svastova

 

 

1:40 PM

40

Matrix Metalloproteinase-2 Modulates Inflammation And Melanoma Progression Via TLR-2

Mansi Saxena, Luciana Muniz-Bongers, and Nina Bhardwaj

 

 

1:50 PM

41

Novel multi-faceted brain metastasis therapy

Manuel Sarmiento Soto, James Larkin, Kleopatra Andreou, and Nicola Sibson

 

 

 

 

 

 

 

2:00 PM

 

Lunch/Informal Discussions

 

 

 

 

 

 

 

3:30 PM

 

City Tour

Buses depart from hotel lobby at 3:30 PM

 

 

 

 

 

 

 

7:30 PM

 

Dinner/Informal Discussions at a local Greek Restaurant

Please note buses do not pick-up at the hotel prior to dinner.

Dinner proceeds right after the tour.

 

 

 

 

 

 

 

Thursday, June 9

 

 

 

 

 

 

 

7:30 AM

 

Breakfast

 

 

 

 

 

 

 

Session VIII

Stress resistance & cancer II: ER stress and the Unfolded Protein Response

Chair: Marianne Koritzinsky

 

 

8:30 AM

42

Oncogenic Stress overrides the circadian clock through UPR-dependent micro-RNA regulation

Yiwen Bu, Chi Van Dang, Costas Koumenis, Serge Fuchs, and Alan Diehl

 

 

8:55 AM

43

The C/EBPdelta transcription factor is a signaling hub for promotion of cancer cell stemness and is regulated by the unfolded protein response

Kuppusamy Balamurugan, Namratha Sheshadri, Shikha Sharan, and Esta Sterneck

 

 

9:20 AM

44

Genome-wide CRISPR screens identifies novel modulators of cell fate during ER stress

Constantinos Koumenis, Souvik Dey, and Lauren Brady

 

 

9:45 AM

45

IRE1-dependent immune surveillance in glioblastoma

Eric Chevet

 

 

10:10 AM

46

The unfolded protein response promotes tolerance to hypoxia through maintenance of mitochondrial and ER homeostasis through ULK1

Dan Cojocari, Ravi Vellanki, Marianne Koritzinsky, and Bradly Wouters

 

 

10:35 AM

47

PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Pre-malignant Granule Cell Precursor Apoptosis

Wensheng Lin

 

 

 

 

 

 

 

10:45 AM

 

Coffee Break/Poster Viewing

 

 

 

 

 

 

 

Session IX

 

Stress resistance & cancer III: Oncogenic stress and signaling

Chair: Esta Sterneck

 

 

11:30 AM

48

Translation initiation factor eIF2α serine 51 phosphorylation couples with the mammalian target of rapamycin (mTOR) to determine cell fate and tumorigenesis under stress

Antonis Koromilas

 

 

11:55 AM

49

The potential of MK2 inhibition in cancer therapy

Lenka Munoz

 

 

12:20 PM

50

Inhibition of EGFR palmitoylation creates EGFR signaling dependency

Eric Witze, Kristin Runkle, Akriti Kharbanda, Xing-Jun Cao, and Ewa Stypulkowski

 

 

12:45 PM

51

Atr inhibition induces DNA damage and apoptosis in medulloblastoma and attenuates tumorigenesis

Patrick Lang, Jaclyn Wu, Jing Gao, Duhyeong Hwang, Alexander Kabanov, Marina Sokolsky-Papkov, and Timothy Gershon

 

 

12:55 PM

52

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas

Yari Ciribilli, Prashant Singh, Reinhard Spanel, Alberto Inga, and Jürgen Borlak

 

 

1:05 PM

 

Crosstalk between p53 family and hypoxia inducible factor in cancer

Ivano Amelio and Gerry Melino

 

 

 

 

 

 

 

 

Session X

 

Meet the experts

Chair: Ravi Amaravadi

 

 

1:15 PM

52

P01 -Multidisciplinary Coordinated Research Program at the National Cancer Institute: Current Status and Future Trends

Konstantin Salnikow

 

 

1:40 PM

53

Getting published in the Nature journals: an Editor’s perspective

Alexia Zaromytidou

 

 

 

 

 

 

 

2:05 PM

 

Closing Remarks

 

 

 

 

 

 

 

2:10 PM

 

Lunch/Informal Discussions

 

 

 

 

 

 

 

8:00 PM

 

Farewell Dinner

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Friday, June 10

 

 

 

 

 

 

7:30 AM

 

Breakfast

 

 

 

 

 

9:00 AM

 

Departure

 

 

 

             

 

 

 

POSTERS

54

A cyclic peptide derived of urokinase receptor generates a potent inhibitor of the growth and invasion  in a mouse model of chondrosarcoma

Domenica Rea and Claudio Arra

55

A metabolomic discovery approach for identification of metabolic changes associated with MET inhibition and DNA damaging agents in MET-addicted and non-MET-addicted cellular systems

Michaela Poliakova, Nicola Zamboni, Aebersold Daniel, Michaela Medova, and Yitzhak Zimmer

56

A novel role for the complement cascade in the resistance of oesophageal adenocarcinoma to chemoradiation therapy

Niamh Lynam-Lennon, Danica Lavin, Becky Bibby, Stephen Maher, John Reynolds, and Jacintha O'Sullivan

57

Aberrant actin stress fibre formation and extracellular milieu modifications prevent local invasion and metastasis formation in response to novel estrone analogues in breast- and cervical cancer cells

Anne Theron, Laurence Lafanechère, Renaud Prudent, and Annie Joubert

58

Association of ascorbate and hypoxia inducible factor-1 in samples from breast cancer patients

Elizabeth Campbell, Gabi Dachs, Helen Morrin, Bridget Robinson, and Margreet Vissers

59

Cancer therapy by promoting differentiation of cancer stem cells

Daniela Pankova

60

Crosstalk between the mutational landscape of an innate immune system pathway and tumor hypoxia

Monica Olcina, Nikolas Balanis, Ryan Kim, Edward LaGory, AJ Venkatakrishnan, David Hewings, Thomas Graeber, and Amato Giaccia

61

Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer

Sabrina Bimonte, Antonio Barbieri, Giuseppe Palma, Antonio Luciano, Claudio Arra, and Francesco Izzo

62

Development of immunomonitoring assays for dendritic cell-based lung cancer immunotherapy

Ondřej Palata, Lenka Sadílková, Naďa Hradilová, Irena Vančurová, Dagmar Myšíková, Hana Mrázková, Robert Lischke, Radek Špíšek, and Irena Adkins

63

Distinct immune status in patients with adenocarcinoma and squamous cell carcinoma: implication for immunotherapy of non-small cell lung cancer

Nada Hradilova, Ondrej Palata, Lenka Sadilkova, Dagmar Mysikova, Hana Mrazkova, Robert Lischke, Radek- Spisek, and Irena Adkins

64

Epigenetic determinants of immunotherapy response

Navneet Singh, Vishnu Modur, Vakul Mohanty, Gang Huang, and Kakajan Komurov

65

ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells

Iman Khan, Byong Yoo, Olivier Masson, Sylvain Baron, Dale Corkery, Graham Dellaire, Laura Attardi, and Kirill Rosen

66

Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines

Kamila Kloudova, Simona Partlova, Anna Fialova, Radek Spisek, and Tomas Brtnicky

67

GCN2 and cell-cycle progression

Cathrine Bøe, Tine Håland, Erik Boye, Randi Syljuåsen, and Beata Grallert

68

Genetic alterations of the siah-1 gene in hepatocellular carcinomas

Neung Hwa Park

69

HGF-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

Deborah Morena, Nicola Maestro, Francesca Bersani, Paolo Forni, Marcello  Lingua, Valentina Foglizzo, Petar Šćepanović, Silvia Miretti, Alessandro Morotti, Jack Shern, Javed Khan, Ugo Ala, Paolo Provero, Valentina Sala, Tiziana Crepaldi, Patrizia Gasparini, Michela Casanova, Andrea Ferrari, Gabriella Sozzi, Roberto Chiarle, Carola Ponzetto, and Riccardo Taulli

70

Human CYP1B1 activates uPAR signaling pathway to promote cancer progression and metastasis in human breast cancer cells

Young-Jin Chun

71

Hypoxia and macrophages modulate cancer cell responses to chemotherapy

Carine Michiels, Francois Clement, Marie Genin, Celine Tellier, Olivier Feron, and Martine Raes

72

Hypoxia in the tumor microenvironment: A formidable saboteur of the anti-tumor immune response

Tsolère Arakelian, Takouhie Mgrditchian, Guy Berchem, Salem Chouaib, and Bassam Janji

73

Identification of novel PGE2 Receptor Antagonists that modulate angiogenesis and inflammation in Oesophageal Adenocarcinoma

Anne-Marie Byrne, Mary-Clare Cathcart, Michelle Lowry, Breandan Kennedy, Nicholas Pullen, James Phelan, Niamh Clarke, John Reynolds, Jacintha Sullivan, and Graham Pidgeon

74

IGF-II mRNA-Binding Protein 3 (IMP3) contributes to glioma stem-like cell maintenance and contributes to chemo-radio resistance by increasing translation of RELA

Shruti Bhargava, Vikas Patil, Abhirami Visvanathan, Anuj Kumar, Shwetha Shivayogi, Alangar Hegde, Bangalore Chandramouli, Arimappamagan Arivazhagan, Saumitra Das, Vani Santosh, and Kumaravel Somasundaram

75

IL-6 effects on expression cell surface molecules on K-562 cells

Vladimir Jurisic and Tatjana Srdic-Rajic

76

Inactivating mechanism of ATBF1 gene in hepatocellular carcinomas

Neung Hwa Park

77

Influence of tumor VEGF isoform expresson on response to a VEGF pathway inhibitor ± radiotherapy

Debayan Mukherjee, William English, Sarah-Jane Lunt, Matthew Fisher, Karina Bingham, Khairul Mohd Khatib, Chryso Kanthou, and Gillian Tozer

78

Inhibition of Flightless 1 reduces tumor growth and spread in a mouse colon cancer model

Noraina Zakuan, Dodie Pouniotis, Jessica Jackson, Zlatco Kopecki, Allison Cowin, and Ian Darby

79

Investigating the role of ATG4B in PDAC growth and survival

Paalini Sathiyaseelan, Steve Kalloger, Daniel Renouf, David Schaeffer, Christopher Hughes, Gregg Morin, and Sharon Gorski

80

Involvement of MET signaling in the HIF-1α pathway

Astrid Glück, Michaela Medová, Eleonora Orlando, Dominic Leiser, Daniel Aebersold, and Yitzhak Zimmer

81

Is there a role for ascorbate in regulating hypoxia factors in renal cell carcinoma?

Christina Wohlrab, Elisabeth Phillips, Helen Morrin, Margreet Vissers, Bridget Robinson, and Gabi Dachs

82

Ketogenic Diet is a potential adjuvant therapy for Neuroblastoma

Sepideh Aminzadeh-Gohari, Rene Feichtinger, Silvia Vidali, Felix Locker, Tricia Rutherford, Maura O'Donnel, Andrea Stöger-Kleiber, Johannes Mayr, Wolfgang Sperl, and Barbara Kofler

83

Magnetic nanoparticles with plasmid DNA encoding shRNA against Mcam for melanoma treatment

Lara Prosen, Samo Hudoklin, Gregor Sersa, Monika Stimac, Ursa Lampreht Tratar, Maja Ota, Janez Scancar, Rok Romih, and Maja Cemazar

84

Manipulating the tumour microenvironment using physiological or pharmacological doses of ascorbate

Gabi Dachs, Elizabeth Campbell, Bridget Robinson, and Margreet Vissers

85

Microfluidic anticancer drug screening with in vivo grown cancer xenografts

Bo Young Jung, Song Cheol Kim, and Chang Mo Hwang

86

MicroRNA-31 regulates chemosensitivity in malignant pleural mesothelioma via altered intracellular drug trafficking and localisation

Stephen Maher, Hannah Moody, and Michael Lind

87

Modulation of tumor microenvironment properties by manipulation with DNA damage response pathway

Oleg Demidov, Anastasia Goloudina, Frédéric Lirussi, Bogdan  Grigorash, Carmen Garrido, and Burhan Uyanik

88

New topoisomerase inhibitor for breast and pancreas cancer

Palma Giuseppe, Mariconda Annaluisa, Rea Domenica, Vitale Del Vecchio, Barbieri Antonio, Michela Falco, Agostino Casillo, Domenico Iacopetta, Maria Stefania Sinicropi, Longo Pasquale, Arra Claudio, and Saturnino Carmela

89

Novel small molecule inhibitors of 5-lipoxygenase are potential therapeutic targets in obesity-driven oesophageal adenocarcinoma

Zivile Useckaite, Emma Allott, Helen Sheridan , David Maloney, John Reynolds, and Graham Pidgeon

90

Predictive value of genetically engineered endogenous mouse models in preclinical therapeutic studies

Aayush Gupta, Evdokia Kalideris Kalideris, Marija Trajkovic-Arsic, Rickmer Braren, and Jens Siveke

91

Reprogramming the transcriptional response to hypoxia

Ishna Mistry and Ali Tavassoli

92

Ribonucleotide reductase favours the RRM2B subunit to maintain DNA replication in hypoxia

Iosifina Foskolou, Christian  Jorgensen, Katarzyna Leszczynska, Monica Olcina, Vincenzo  D’Angiolella, William Myers, Carmen Domene, Emily Flashman, and Ester Hammond

93

Skin based gene delivery for tumor treatment

Spela Kos, Maja Cemazar, Tanja Blagus, Urska Kamensek, Simona Kranjc, and Gregor Sersa

94

Strain analysis in the assessment of mouse model of cardiotoxicity by chemotherapy: sample for preclinical research

Domenica Rea and Claudio Arra

95

Synthesis and biological evaluation of a noval anticancer drug delivery system: Poly (L-γ-glutamyl- L-Carbocisteine)-Paclitaxel Nanoconjugate

Yiting Wang, Jing Wang, Lei Yu, Hui Peng, and Jianzhong Zhu

96

Synthesis, Characeration and biological evaluation of a nano carbon quantum

Lei Yu, Jing Wang, Yiting Wang, Hui Peng, and Jianzhong Zhu

97

The clinicopathological significance of monocarboxylate transporters (MCTs) and CD147 in germ cell tumors

Eduardo da Silva, Flavio Cárcano, Fátima Baltazar, Filipa Morais-Santos, Luiz Lopes, Cristovam  Scapulatempo-Neto, and CélinePinheiro

98

The role of ceramide galactosyltransferase (UGT8) and galactosylceramide (GalCer) in cellular stress response and multidrug-resistance of breast cancer cells

Bartlomiej Kocbach, Ida Szmigiel, Jaroslaw Suchanski, Pawel Pasikowski, Piotr Dziegiel, and Maciej Ugorski

99

The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells

Sabrina Bimonte, Antonio Barbieri, and Francesco Izzo

100

The role of miRNAs in the transcriptional program and aggressive tumor phenotype associated with hypoxia and lactic acidosis in cervical cancer

Heidi Lyng, Marte Jonsson, Anja Nilsen, Malin Forsberg, Gunnar Kristensen, and Cathinka Julin

101

The role of podoplanin expressed cancer-associated fibroblasts on the progression of breast cancer

Jarosław Suchański, Maciej Zacharski, Piotr Dzięgiel, and Maciej Ugorski

102

The role of Prolactin-Induced Protein (PIP) in apoptosis of breast cancer cells induced by doxorubicin

Anna Urbaniak, Jaroslaw Suchanski, Piotr Dziegiel, and Maciej Ugorski

103

The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

Antonio Barbieri, Sabrina Bimonte, Giuseppe Palma, Antonio  Luciano, Domenica Rea, Giosue Scognamiglio, Sisto Perdonà, Silvia Zappavigna, Paola Stiuso, Michele Caraglia, and Claudio Arra

105

Immunogenic Cell Death induction in melanoma cells: a valuable therapeutic approach in both wild type and oncogenic BRAF cells

Paola Giglio, Mara Gagliardi, Mauro Piacentini, and Marco Corazzari