Wednesday, September 27

6:00 PM

Conference Registration

8:00 PM

Welcome Reception and Dinner

Thursday, September 28

7:30 AM

Breakfast

8:25 AM

Welcome and Opening Remarks

SESSION I

Epigenetics

Chair: Marjorie Brand

8:30 AM

1

Molecular mechanisms for assembling and resolving human naïve Pluripotency

Jacob Hanna

8:55 AM

2

Epigenetic controls of cell plasticity and commitment

Tiziana Brevini, Elena Manzoni, Alessandro  Zenobi, and Fulvio Gandolfi

9:20 AM

3

Epigenetic histones modifications controlling cell fate in muscle regeneration

F Jeffrey Dilworth and Yuefeng Li

9:45 AM

4

Transcriptional and epigenetic mechanisms controlling blood lineage specification.

Catherine Porcher

10:10 AM

5

Activation and repression in reprogramming to pluripotency

Miguel Angel Esteban

10:35 AM

6

Transcriptional programming and re-programming of Cardiomyocyte fate

Zhihong Xue, Gizem Rizki, Wei-Chih Tsai, Vincent Butty, and Laurie A Boyer

11:00 AM

Coffee Break & Poster Viewing

SESSION II

Muscle Regeneration

Chair: Jeffrey Dilworth

11:30 AM

7

Regulation of the skeletal muscle stem cell niche

Shahragim Tajbakhsh

11:55 AM

8

Regulation of muscle stem cell function during tissue repair

Alessandra Sacco, Matthew Tierney, Michael Stec, Steffen Rulands, and Benjamin Simons

12:20 PM

9

Probing the satellite cell compartment

Michael Kyba

12:45 PM

10

Muscle stem cell regenerative decline with aging

Laura García-Prat, Antonio Serrano, Eusebio Perdiguero, and Pura Muñoz-Cánoves

1:10 PM

11

Role of stromal cells in homeostasis, regeneration and fibrosis

Hesham Soliman, Elena Groppa, Chihkai Chang, Wilder Scott, Michael Underhill, and Fabio Rossi

1:35 PM

12

Cross-talk between macrophages and satellite cells

Benedicte Chazaud

2:00 PM

Lunch and Informal Discussions

7:30 PM

Dinner and Informal Discussions

Friday, September 29

7:30 AM

Breakfast

SESSION III

Blood

Chair: Claudia Waskow

8:30 AM

13

Lymphocyte development and lineage commitment in the embryo

Ana Cumano, Claire Berthault, Cyrille Ramond, Odile Burlen-Defranoux, Rachel Golub, Paulo Vieira, and Pablo Pereira

8:55 AM

14

Bioactive SL-13R peptide expands human umbilical cord blood hematopoietic stem cells and maintains long-term reconstitution ability

Daisuke Sugiyama, Ayako Yumine, and Yoichi Nakanishi

9:20 AM

15

Tissue engineered disease models using human iPSC-derived myocardial cells for personalized medicine

Aylin Acun

9:30 AM

16

Cross-talk between embryonic and adult hematopoiesis  - embryo-derived macrophages regulate the dendritic cell pool size in the adult spleen

Claudia Waskow

9:55 AM

17

Regulation of mesenchymal stem cell differentiation by nanopatterning

Themis Kyriakides

10:05 AM

18

A novel model of human lymphomyeloid progenitor hierarchy based on single cell functional and transcriptional analysis 

Paresh Vyas

10:30 AM

19

Understanding cell fate decisions in erythropoiesis using quantitative mass spectrometry and single-cell mass cytometry

Marjorie Brand, Carmen Palii, Mark Gillespie, Daniel Sanchez-Taltavull, Theodore Perkins, Jeff Ranish, and Doug Higgs

11:00 AM

Coffee Break and Poster Session

SESSION IV

Disease

Chair: Michael Kyba

11:45 AM

20

Induction of pluripotent and multipotent stem cells

Hans Schöler

12:10 PM

21

HBL1 is a human-specific long non-coding RNA that modulates human cardiomyocyte development by counteracting MIR1

Juli Liu, Yang Li, Bo Lin, Yi Sheng, and Lei Yang

12:20 PM

22

Inducible and deterministic forward programming of human pluripotent stem cells into neurons, skeletal myocytes, and oligodendrocytes

Matthias Pawlowski, Daniel Ortmann, Alessandro Bertero, Joana Tavares, Roger Pedersen, Ludovic Vallier, and Mark Kotter

12:45 PM

23

Regenerative capacities of adipose stem cells in ischemia

Nagwa El-Badri, Ahmed El-Badawy, and Toka AbdelRahman

1:10 PM

24

Cellular reprogramming approaches for cardiovascular disease

Deepak Srivastava

1:35 PM

25

Gene editing of patient-specific iPS cells and therapeutic application in muscular dystrophies

Rita Perlingeiro

2:00 PM

Lunch and Informal Discussions

7:30 PM

Dinner and Informal Discussions

Saturday, September 30

7:30 AM

Breakfast

SESSION V

Niche/Signaling

Chair: Ondine Cleaver

8:30 AM

26

Applying niche concept in stem cell therapy

Ting Xie

8:55 AM

27

The Hippo pathway regulates epithelial proliferation via NFkB to coordinate pancreas morphogenesis

Ondine Cleaver and Caitlin Braitsch

9:20 AM

28

Diverse regenerative strategies of the intestinal epithelium

Ophir Klein

9:45 AM

29

Decoding cellular signals: irreversible commitment during hES cells differentiation

Alexandra Gunne-Braden, Rahuman Sheriff, Borzo Gharibi, Roy Wollman, and Silvia Santos

9:55 AM

30

Placental Cdx2 cells in cardiac regeneration

Sangeetha Vadakke Madathil, Amaresh Ranjan, Jesse Yoon, Joseph Tripodi, Koen Raedschelders, Sarah Parker, Vesna Najfeld, Jennifer  Van Eyk, Gina Larocca, and Hina Chaudhry

10:20 AM

31

Stem cell like self-renewal and aging mechanisms in macrophages

Michael Sieweke

10:45 AM

Coffee Break and Poster Session

SESSION VI

Reprogramming

Chair: Andras Nagy

11:30 AM

32

A solution for cell therapy safety; paving the way to the clinic

Andras Nagy

11:55 AM

33

Transposable elements refine human preimplantation embryogenesis

Zsuzsanna Izsvak, Manvendra Singh, Jose Luis García Pérez, and Laurence Hurst

12:20 PM

34

Systems Biology Approaches to Cellular Conversion

Antonio del Sol

12:45 PM

35

A Chemical Approach to Controlling Cell Fate 

Sheng Ding

1:10 PM

36

A chemical screen identifies a role for P300 and CBP in reprogramming

Tamer Onder

1:35 PM

37

Human pluripotent stem cells with improved functional pluripotency and interspecies chimera potential

Elias Zambidis

2:00 PM

Lunch and Informal Discussions

3:30 PM

City Tour

7:30 PM

Dinner and Informal Discussions

Sunday, October 01

7:30 AM

Breakfast

SESSION VII

Neuroscience

Chairs: Yechiel Elkabetz

8:30 AM

38

Building the mammalian embryo in vivo and in vitro

Magdalena Zernicka-Goetz

8:55 AM

39

Proneural genes maintain a neural stem cell pool through multilineage priming

Sisu Han, Grey Wilkinson, Saiqun Li, Lata Adnani, Satoshi Okawa, Vladimir Espinosa Angarica, Dawn Zinyk, Yaroslav  Ilnytskyy, Matthew Brooks, Daniel Dennis, Rajiv Dixit, eko Raharjo, Faizan Malik, Jung-Woong  Kim, Wei Wu, Waleed Rahmani, Jennifer Chan, Deborah Kurrasch, Anand Swaroop, Igor Kovalchuk, Antonio del Sol, Jeff Biernaskie, and Carol Schuurmans

9:20 AM

40

Tweaking the vertebrate neural stem cells for efficient neuroregeneration

Caghan Kizil

9:45 AM

41

Zika virus infection in neuroprogenitor (NPC) cells: What did we learn from twin studies?

Mayana Zatz

10:10 AM

42

Meaningful Modeling of Cortical Development and Microcephaly in Rosettes and Organoids Derived by Combined Pathway Inhibition

Yechiel Elkabetz

10:35 AM

43

Using stem cells to model neurological disease & advance personalized medicine

Evan Snyder

11:00 AM

Coffee Break

SESSION VIII

Disease

Chairs: Laurie Boyer

11:30 AM

44

In vitro modeling of aniridia-related Pax6 haploinsufficiency by the use of CRISPR/Cas9 on limbal epithelial cells

Daniel Aberdam

11:55 AM

45

Gene Editing of Stem Cells from Cystic Fibrosis Patients

Brian Davis

12:20 PM

46

Genetic rescue of mitochondrial and skeletal muscle impairment in an iPSCs model of coenzyme Q10 deficiency

Pablo Menendez Bujan

12:45 PM

47

From decellularized scaffolds to bioengineered organs

Yasar Murat Elcin

1:10 PM

48

iPSC for the Derivation of Motile Ciliated Cells and Applications for Lung Disease

Amy Firth

1:35 PM

49

Clinical Trials in Pluripotent Stem Cells

Alan Trounson

1:55 PM

Closing Remarks

2:00 PM

Lunch and Informal Discussions

8:00 PM

Farewell Dinner

Monday, October 2

8:00 AM

Breakfast

10:00 AM

Departure

50

Single-cell expression profiling reveals a dynamic state of embryonic cardiac multipotent cells

Ioannis Kokkinopoulos, Kenta Yashiro, Hidekazu Ishida, and Rie Saba

51

Hyaluronic acid-based nano sphere improves cardiac function in acute myocardial infarcted rat model

Ki Sung Hong

52

Epithelial plasticity control in tissue stem cells – lessons from skin and mammary gland

Xing  Dai

53

Safety of mesenchymal stem cells  therapy  – potential risk  of spontaneous transformation

Katarzyna Drela, Adam Nowakowski, Mikolaj Wrobel, Miroslaw Wielgos, and Barbara Lukomska

54

DNA methylation analysis of Sox2 regulatory regions during osteogenic differentiation of mouse embryonic stem cell

Sajida Batool

55

The role of progranulin on the human dopaminergic neuronal differentiation

Hsiao-Nan Hao, Haitao Pei, Jean Peiduzzi-Nilson, Peter Hao, and Jane Hao

56

Selected herbal extracts as potential stimulants for human mesenchymal stem cell proliferation

Vindya Udalamaththa, Udaya Samaratunga, Preethi  Soysa, Sumedha Wijeratne, and Preethi Udagama

57

Neuroregenerative properties of human Wharton’s jelly - mesenchymal stem cells cultured  in 3D fibrin scaffolds on post-ischemic organotypic hippocampal slices

Patrycja Obtulowicz, Marzena Zychowicz, Anna Figiel-Dabrowska, Hanna Winiarska, Leonora Buzanska, and Anna Sarnowska

58

A novel cardiovascular multipotent cell population isolated during ESCs differentiation based on VE-cadherin promoter activity

Violetta Maltabe, Eleonora Barka, Marianthi Kontonika, Simeon  Agathopoulos, Theofilos Kolettis , and Panos Kouklis

59

Towards in vitro modelling of early mouse development

Mehmet Girgin, Peter Baillie-Johnson, Alfonso Martinez-Arias, and Matthias Lutolf

60

Comparative studies of human pluripotent stem cell culture conditions for maximizing cell survival in maintenance, expansion and single cell cloning

Maria Mileikovskaia, Claudio Monetti, Huijan Yang, and Andras Nagy

61

Influence of different oxygen concentration and type of 3D microenvironment on human Wharton’s Jelly Mesenchymal Stem Cells

Wioletta Lech, Marzena Zychowicz, Patrycja Obtulowicz, Krystyna Domanska-Janik, and Leonora Buzanska

62

TAL1 interferes with the T cell regulatory function of BCL11B to mediate leukemic transformation in T-ALL

Carmen Palii, Alphonse Chu, Michelle Kelliher, Theodore Perkins, and Marjorie Brand

63

Optimization of human Induced pluripotent stem cell-derived cardiomyocytes for tissue engineering and disease modeling

Aylin Acun, Pinar Zorlutuna, and Trung Dung Nguyen

64

Zac1 is essential to maintain Muller glia in a quiescent stem cell state in the retina

Yacine Touahri, Nobuhiko  Tachibana,  Lata Adnani, Mary Chute, Rajiv Dixit,  Dawn Zinyk,  Miriam Reisenhofer, Volker Enzmann, Jeff Biernaskie, Laurent Journot, Yves Sauve, and  Carol Schuurmans

65

Verification of Wharton’s jelly mesechymal stem cells secretory responses to specific microenvironment in vitro

Anna Figiel-Dabrowska, Wioletta Lech, Marzena Zychowicz, Leonora Buzanska, Krystyna Domanska-Janik, and Anna Sarnowska

66

Wharton jelly mesenchymal stem cells from the human umbilical cord: isolation, characterization and their differentiation into functional endothelial cells

Kemal Baysal, Ozge Tezcan, Pinar  Ercetin, Pinar Akan, and Deniz Oztekin

67

The pathophysiological role of MicroRNAs in diabetic cardiac stem cells

Nima Purvis, Andrew Bahn, and Rajesh Katare

68

Novel serum-free,  xeno-free vitronectin-based culture system for hPSC

Sharon Daniliuc, Mira Genser-Nir, Yulia Miropolski, Maria Sharovetsky, Marina Tevrovsky, Roni Hasan Brill, and David Fiorentini

69

lysosomal signalling is essential for embryonic stem cell differentiation and human development

Florian Villegas and Joerg Betschinger