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Friday, September 21 |
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6:00 PM |
Conference Registration |
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8:00 PM |
Welcome Reception and Dinner |
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Saturday, September 22 |
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8:00 AM |
Breakfast |
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SESSION I |
Systems Metabolism and Functional Biomarkers in Health and Disease Chair: Amanda MacFarlane |
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9:00 AM |
1 |
Systems biology is the future of human nutrition Patrick Stover |
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9:25 AM |
2 |
Phenotypic noise in metabolic systems Joe Nadeau and Jesse Riordan |
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9:50 AM |
3 |
Fine-grained insight into an individual’s metabolic state by in vivo stable-isotope labeling. Karsten Hiller |
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10:15 AM |
4 |
Metabolomic analyses of indicators of cardiometabolic disease and associations with the gut microbiome and diet Clary Clish |
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10:40 AM |
5 |
Metabolic biomarkers of metabolic disease for population and patient stratification Julian Griffin |
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11:05 AM |
6 |
The fallacy of using arbitrary safety (uncertainty) factor of “100” to derive upper limits of safe intake for nutrients, such as L-amino acids Miro Smriga |
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11:20 AM |
Coffee Break |
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SESSION II |
Nutrition, gut, and microbiome Chair: Christian Metallo |
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12:00 PM |
7 |
The microbiome as a key component of precision nutrition Rob Knight |
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12:25 PM |
8 |
Diet, the gut microbiome, and its metabolome in health and disease Gary Wu |
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12:50 PM |
9 |
Sphingolipid production by gut microbiota regulates liver ceramide metabolism Stacey Heaver, Ruth Ley, and Elizabeth Johnson |
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1:15 PM |
10 |
A host gene-microbe interaction potentially relevant to personalized nutrition Angela Poole, Julia Goodrich, Nicholas Youngblut, Guillermo Luque, Jessica Sutter, Jillian Waters, Qiaojuan Shi, Mohamed El-Hadidi, Lynn Johnson, Haim Bar, Daniel Huson, James Booth, and Ruth Ley |
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1:40 PM |
11 |
Microbial systems ecology for identifying key functions driving host-microbiome-diet interactions Paul Wilmes |
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2:05 PM |
12 |
Prebiotic diet restores metabolism and reduces risk for Alzheimer’s disease by modulating gut microbiome in an APOE4 mouse model Lucille Yanckello, Jared Hoffman, Ishita Parikh, Jessie Hoffman, Stefan Green, George Chlipala, and Ai-Ling Lin |
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2:20 PM |
Lunch and Informal Discussions |
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7:30 PM |
Dinner and Informal Discussions Buses depart from the hotel lobby at 7:30 PM |
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Sunday, September 23 |
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8:00 AM |
Breakfast |
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SESSION III |
Biomarkers of Healthy Aging and Metabolic Disease Chair: Andrew Prentice |
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9:00 AM |
13 |
Improving metabolic health through precision dietetics David Threadgill |
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9:25 AM |
14 |
Lipidomics analysis identifies key regulatory enzymes in health and disease Michael Wakelam |
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9:50 AM |
15 |
Unbiased high-throughput screening approaches to combat mitochondrial and metabolic disease Joeva Barrow, Eduardo Balsa, Meghan Soustek, Francisco Verdeguer, Clint Tavares, Louis Hollingsworth IV, Mark Jedrychowski, Rutger Vogel, Jan Smeitink, Joao Paulo, Steven Gygi, John Doench, David Root, and Pere Puigserver |
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10:15 AM |
16 |
Cellular aging contributes to failure of cold-induced beige adipocyte formation Daniel Berry |
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10:40 AM |
17 |
Metabolic dysfunction and human disease phenotypes Ralph DeBerardinis |
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11:05 AM |
18 |
Endogenous synthesis of erythritol, a low calorie sweetener, in humans Lisa Schlicker, Jean-Pierre Trezzi, Christian Jaeger, Martha Field, Patricia Cassano, Patrick Stover, Karsten Hiller, and Katie Hootman |
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11:20 AM |
19 |
Enzyme promiscuity drives monomethyl branched-chain fatty acid synthesis in adipose tissues Martina Wallace, Courtney Green, Lindsay Roberts, Yujung Lee, Justin McCarville, Janelle Ayres, Daniel Nomura, Rohit Loomba, and Christian Metallo |
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11:35 AM |
Coffee Break |
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SESSION IV |
Etiology of Heterogeneity of Response to Nutrients and Diets Chair: Karsten Hiller |
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12:00 PM |
20 |
Endogenous production of erythritol and its association with weight gain Martha Field, Lisa Krämer, and Karsten Hiller |
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12:25 PM |
21 |
omics-based studies of nutritional needs and metabolic diseases in Chinese Xu Lin |
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12:50 PM |
22 |
Circadian dysregulation links nutrition stress and insulin resistance Chaodong Wu |
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1:15 PM |
23 |
Twin metabolomics: the key to unlocking complex phenotypes in nutrition research Aifric O’Sullivan |
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1:40 PM |
24 |
Implementing precision dietetics to predict metabolic health in a genetically heterogeneous mouse model Anna Salvador, William Barrington, and David Threadgill |
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1:55 PM |
25 |
Study of association of RS6923761 polymorphism in GLP1R gene with insulin and c-peptide level in patients with type 2 diabetes Maria Vulf, Daria Skuratovskaya, Elena Kirienkova, Pavel Zatolokin, and Larisa Litvinova |
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2:10 PM |
Lunch and Informal Discussions |
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7:30 PM |
Dinner and Informal Discussions Buses depart from the hotel lobby at 7:30 PM |
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Monday, September 24 |
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8:00 AM |
Breakfast |
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SESSION V |
Nutrients in Epigenetic Programming and Adaptation Chair: Martha Field |
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9:00 AM |
26 |
Nutritional influences on epigenetic programming of the very early human embryo Andrew Prentice |
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9:25 AM |
27 |
Epigenetic regulation of POMC as a metastable epiallele Peter Kuhnen |
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9:50 AM |
28 |
Using precision nutrition to target epigenetic readers, writers, and erasers: a BET/BRD9 acetyl switch on CCAR2 Roderick Dashwood |
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10:15 AM |
29 |
Characterizing the role of PKM2 in muscle progenitor cells Jamie Blum, Brandon Gheller, Henry Le, Seok Eun Jennie Yi, and Anna Thalacker-Mercer |
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10:30 AM |
30 |
microbial bioactives alter cellular metabolism Stefan Christen and Sofia Moco |
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10:45 AM |
31 |
The phytohormone N6-benzyladenosine phosphate is a direct activator of AMP-activated protein kinase Simona Bartova, Matthew Sanders, Prasad Chaskar, Yann Ratinaud, Denis Barron, Kei Sakamoto, and Sofia Moco |
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11:00 AM |
Coffee Break |
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SESSION VI |
Altered Metabolism and Conditional Nutrient Needs in Disease, Trauma and Tissue Regeneration Chair: Clary Clish |
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11:30 AM |
32 |
Metabolism and epigenetics: Novel approaches for epilepsy prevention Detlev Boison |
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11:55 AM |
33 |
The essentiality of serine and glycine for skeletal muscle regeneration Anna Thalacker-Mercer, Jamie Blum, and Brandon Gheller |
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12:20 PM |
34 |
(Non)essential amino acid dependencies in cancer Oliver Maddocks |
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12:45 PM |
35 |
Exploiting enzyme promiscuity via targeted nutrition to combat disease Christian Metallo |
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1:10 PM |
36 |
Towards IMP 2.0: the Integrated Multi-omics Pipeline refactored using the conda framework for HPC-based applications Deepti Mittal, Yohan Jarosz, Shaman Narayasamy, Susana Martinez Arbas, Cedric Laczny, Anna Heinzt-Buschart, Patrick May, and Paul Wilmes |
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1:25 PM |
37 |
Alzheimer’s disease and APOE genotype associated with metabolites related to metabolic syndrome, mitochondrial dysfunction, and kidney dysfunction Tyler Hammond, Ishita Parikh, Peter Nelson, Scott McCulloch, and Ai-Ling Lin |
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1:40 PM |
38 |
Effects of Impaired One Carbon Metabolism on Peripheral Neuropathy in a Mouse Model of Type 2 Diabetes Eunice B Awuah, Martha S Field, and Patrick J Stover |
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1:55 PM |
Lunch and Informal Discussions |
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3:30 PM |
City Tour |
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Buses depart from hotel lobby at 3:30 PM |
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8:00 PM |
Dinner and Informal Discussions Please note that buses do not pick-up at the hotel prior to dinner. Dinner proceeds right after the tour |
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Tuesday, September 25 |
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8:00 AM |
Breakfast |
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SESSION VII |
Precision Nutrition and Enabling Technologies and Comp Modeling Chair: Patrick Stover |
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9:00 AM |
39 |
Metabolomics, biobanking, quality control and metabolism research Thomas Illig |
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9:25 AM |
40 |
TBD Corrado Priami |
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9:50 AM |
41 |
Automatic methods for nutritional assessment, and a case study with soccer players Dag Johansen, Haavard Johansen, and Lars Brenna |
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10:15 AM |
42 |
Capturing global responses to nutrient stimuli with quantitative proteomics Nate Vacanti |
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10:40 AM |
43 |
Shmt1 knockout in HeLa cells induces upregulation of salvage dTMP synthesis, dUTPase, and repair James Chon, Martha Field, Jabez Gondokusumo, Asante Quintana, and Patrick Stover |
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10:55 AM |
44 |
Personalized lifestyle intervention for improving functional health outcomes: LIFE-HOUSE protocol utilizing a tent-umbrella-bucket design Joseph Lamb, Michael Stone, Deanna Minich, Nikky Contractor, Brent Eck, and Jeffrey Bland |
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11:10 AM |
Coffee Break |
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SESSION VIII |
Systems Approaches and Challenges in Establishing Nutrient and Dietary Requirements in Heterogeneous Populations Chair: Ann Yaktine |
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11:45 AM |
45 |
Integrating chronic disease into the DRI model: challenges and options Ann Yaktine |
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12:10 PM |
46 |
Human metabolic phenotypes assessed by plasma metabolomics Daniel Hannelore |
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12:35 PM |
47 |
The role of metabolomics and phenotyping in delivering Precision Nutrition Lorraine Brennon |
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1:00 PM |
48 |
The Role of Agriculture in Precision Nutrition Pam Starke-Reed |
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1:25 PM |
49 |
From population to personalized nutrition: A paradigm shift for developing recommendations for optimal health Amanda MacFarlane |
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1:50 PM |
50 |
Spermicidal efficacy of iodine exposure on male reproductive system: Future perspectives to be explores as non-hormonal male contraceptive Arijit Chakraborty and Kiran Singh |
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2:05 PM |
Closing Remarks |
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2:15 PM |
Lunch and Informal Discussions |
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8:00 PM |
Farewell Dinner |
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Wednesday, September 26 |
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8:00 AM |
Breakfast |
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Departure |