Friday, October 11, 2019
7:30 – 8:00 Breakfast
Immune Dysfunction and Precision Modulation in Trauma and Sepsis (IFSS – China Shock) (Auditorium)
Chairs: Yong-Ming Yao, China / Timothy Billiar, USA
08:00 - 08:20 Host immunosuppression and its precision regulation in postburn sepsis (Y.-M. Yao, China)
08:20 - 08:40 Caspase-11-mediated pyroptosis promoted DIC in sepsis (B. Lu, China)
08:40 - 09:00 Copy number variation of DEFA1/DEFA3: how genetic background impacts sepsis development and its precision treatment (X.-M. Fang, China)
09:00 - 09:20 Endotoxin inhibition of neutrophil chemotaxis: increased autocrine ATP signaling enhances myosin light chain phosphorylation (B.-W. Sun, China)
09:20 - 09:30 Functional immune monitoring in severely injured patients - a pilot study (R. Halbgebauer, Germany)
09:30 - 09:40 A novel insight into agmatine: multitasking in post-traumatic immunodysfunction, systemic inflammatory response and sepsis (H. Liang, China)
09:40 - 09:50 Metabolic rewiring of airway epithelial cells modulates inflammatory responses to the bacterial component flagellin (I. Ramirez-Moral, Netherlands)
09:50 - 10:00 Immunomodulatory therapy of necrotizing pancreatitis with beta-D-glucan (N. Koliakos, Greece)
10:00 – 10:30 Coffee Break
Hermes: Sepsis / Trauma Around the World
(IFSS – Latin America) (Auditorium)
Chairs: Reinaldo Salomao, Brazil / Stefanie Flohe, Germany
10:30 - 10:50 Sepsis in low and middle income countries: how to reduce the inequalities?
(R. Salomao, Brazil)
10:50 - 11:10 Sepsis in Europe (M. Bauer, Germany)
11:10 - 11:30 Is multi-organ failure protective? (M. Singer, United Kingdom)
11:30 - 11:40 Pathogen- and damage-associated molecular patterns are immune modified by apoptotic cell adjuvant therapy for acute sepsis in a cecal ligation and puncture mice model, avoids multi-organ failure and improves survival (D. Mevorach, Israel)
11:40 - 11:50 Inhibition of TLR4/MyD88/TAK1/NF-κB/COX-2 pathway activation contributes to protective effect of bexarotene, a RXR agonist, against lipopolysaccharide-induced inflammatory hyperalgesia (S. Senol, Turkey)
11:50 - 12:00 Mitochondrial respiration and circulating mtDNA levels may help improve early diagnosis of sepsis in burn patients (David Burmeister, USA)
12:00 - 12:10 Immune modulation and CMV reactivation in sepsis-induced immunosuppression (G. Lambe, India)
12:10 - 12:20 Rational designed endogenous antimicrobial peptides in the treatment of sepsis (G. Luo, China)
12:20 - 12:30 A spleen-liver axis drives TNF-alpha production in endotoxemia (A. Steiner, Brazil)
12:30 – 13:30 Lunch
13:30 - 14:30 General Assembly ESS (Auditorium)
Markus Huber-Lang, Germany / Evangelos Giamarellos-Bourboulis, Greece / Inge Bauer, Germany / Marcin Osuchowski, Austria
European Collaborative Shock Research (Auditorium)
Chairs: Karim Brohi, UK / Federico Aletti, USA
14:30 - 14:45 INTRIN / London (K. Brohi, UK)
14:45 - 15:00 CRC1149 Trauma (A. Ignatius, Germany)
15:00 - 15:15 Network Trauma Research (NTF) (B. Relja, Germany)
15:15 - 15:30 TREAT (K. Horst, Germany)
15:30 - 15:45 EGIS (European Group for Immunology of Sepsis) (J. Mermejo-Martin, Spain)
15:45 - 16:00 Center TBI (M. Maegele, Germany)
16:00 - 16:15 Hellenic Institute for the Study of Sepsis (E. Giamarellos-Bourboulis, Greece)
16:15 - 16:30 EU – Shockomics (F. Aletti, USA)
16:30 – 17:00 Coffee Break
ESS 2030 / IFSS 2030: Hades or Olymp?
Past – Presence - Future (Auditorium)
Chairs: Inge Bauer, Germany / Heinz Redl, Austria
17:00 - 17:10 Past ESS (J.-M. Cavaillon, France / H. Redl, Austria)
17:10 - 17:20 Present ESS (I. Bauer, Germany)
17:20 - 17:30 Future ESS - Quo vadis? (M. Huber-Lang, Germany)
17:30 - 17:40 Past IFSS (I. Chaudry, USA)
17:40 17:50 Present IFSS (S. Bahrami, Austria)
17:50 - 18:00 Future IFSS - Quo vadis? (Y.M. Yao, China)
18:00 - 18:10 Discussion
18:10 - 18:20 Special Honors
18:20 - 18:30 Closing remarks (E. Giamarellos-Bourboulis, Greece)
20:00 – 23:45 Farewell Dinner
Parallel Session (Seminar Room)
Friday, October 11, 2019
Hellenic Sepsis Study Group Meeting (English)
Chairs: Iraklis Tsangaris, Greece / Charalombos Gogos, Greece
08:00 - 08:15 Platelets and anti-platelets in sepsis (K. Akinisoglou, Greece)
08:15 - 08:40 New antimicrobials to combat resistance (G. Dimopoulos, Greece)
08:40 - 09:00 The interaction between the immune response and the vascular endothelium in septic shock: a two-way street? (J. Bermejo-Martin, Spain)
09:00 - 09:20 How early vascular endothelium informs of the advent of sepsis? The PROUD study (E. Giamarollos-Bourboulis, Greece)
09:20 - 09:35 A randomized prospective clinical trial to assess the role of procalcitonin-guided antimicrobial therapy to reduce long-term infections sequelae: Results of the PROGRESS trial
(E. Kyriazopoulou, Greece)
09:35 - 09:50 Personalized immunotherapy in sepsis: how to study? (E. Giamarellos-Bourboulis, Greece)
09:50 - 10:00 Institutional anticoagulation protocol for septic DIC is associated with differences in in-hospital mortality: J-SEPTIC DIC study (a nation-wide registry study) (K. Tanaka, Japan)
10:00 – 10:30 Coffee Break
IFSS - Russian Shock SSSR (Russian – English translation)
Chair: Vladimir Pisarev, Russia
10:30 - 10:55 Perfluorancarbones in critical care (V. Moroz, Russia)
10:55 - 11:20 Shock: clinical and anatomical analysis (A. Golubev, Russia)
11:20 - 11: 45 Septic shock: problems of pathogengesis, diagnosis, and treatment
(V. Kulabuchov, Russia)
11:45 - 11:55 Nosocomial pneumonia: role in septic shock development (A. Kuzovlev, Russia)
11:55 - 12:05 Metabolic alterations in traumatic shock: correction by deferoxamin (V. Dolgih, Russia)
12:05 - 12:15 Microbiota as an organ and the role of its total dysfunction in septic shock (N. Beloborodova, Russia)
12:15 - 12:25 #120 Young scientist study: Specificity of gut microbiota in critically ill patients: quantity, quality and function (E. Chernevskaya, Russia)
12:25 - 12:30 Closing remarks (V. Pisarev, Russia)
12:30 – 13:30 Lunch
Friday, October 11, 2019
IFSS- Russian Shock SSSR (Russian – English translation)
Chairs: Artem N. Kuzovlev, Russia
14:30 - 14:55 Genetic and immune regulation biomarkers in sepsis and shock patients
(V. Pisarev, Russia)
14:55 - 15:20 Endotoxicosis as a course of shock development (A. Lodiagin, Russia)
15:20- 15:45 Critical illness in acute poisoning with narcotic drugs (G. Livanov, Russia)
15:45 - 15:55 Endotoxic shock in acute poisoning with the cauterizing substances
(B. Batocirenov, Russia)
15:55 - 16:05 Strategy of prevention of the intra-surgery massive hemorrhage in children
(E. Spiridonova, Russia)
16:05 - 16:15 Cardiogenic shock at a prehospital stage: management and prevention
(A. Zakcharova, Russia)
16:15 - 16:25 Young scientist study: Microvascular alterations in rat skin during hemorrhagic shock and after resuscitation with autologous blood and crystalloids (I. Ryzhkov, Russia)
16:20 - 16:30 The prescription of phosphocreatine in patients with septic shock improves parameters of hemodynamics and reduces the degree of hypoxia (V. Slepushkin, Russia)