Saturday May 14, 2022
7:00 pm Conference Registration
8:00 pm Welcome Reception and Dinner
Sunday May 15, 2022
8:00 am Breakfast
Chair: Joseph Lorenzo/ Natalie Sims
9:00 am: “Innate and adaptive immune responses in the bone marrow – live and in color”
Matthias Gunzer
University Duisburg-Essen, Germany
9:40 am “A stem cell basis for osteoblast versus adipocyte lineage commitment”
Matthew B. Greenblatt
Weill Cornell Medical College, USA
10:20 am: “Parathyroid hormone receptor signaling in osteoblast lineage support of hematopoiesis”
Joy Wu
Stanford Medicine, USA
11:00 am Coffee Break
11:30 am “Inspiration by non-canonical models for skeletal biology”
Andrei Chagin
Karolinska Institute, Sweden
Short Talks
12:10 pm "IL-23 induced GDF15 contributes to trabecular bone loss, but does not affect skin, gut or joint inflammation"
Renee Van der Cruyssen
Ghent University, Belgium
12:30 pm "Supplementation with a single Bifidobacterium accelerates bone repair in aged mice"
Joseph Roberts
Emory University, USA
12:50 pm "Bone-specific alterations in tumour-intrinsic immune signalling in metastatic prostate cancer"
Katie Owen
Peter MacCallum Cancer Institute, Australia
1:10 pm "Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation"
Gowrishankar Muthukrishnan
University of Rochester Medical Center, USA
1:30 pm "Utilizing microbe-derived agents to modulate inflammation and skew osteogenesis in ceramic-based bone substitutes"
Nada Rahmani
University Medical Center Utrecht, Netherlands
1:50 pm Lunch and Informal Discussion
7:30 pm Dinner and Informal Discussion
Monday May 16, 2022
8:00 am Breakfast
Chair: Yongwon Choi/ Georg Schett
9:00 am: “Joint pain: a conversation between nerves, bone, and immune cells?”
Anne Marie Malfait
Rush Medical College, USA
9:40 am “Elucidating the Osteoimmunology of S. aureus Bone Infection and Development of a Vaccine”
Edward Schwarz
University of Rochester Medical Center, USA
10:20 am: “Parsing the paradoxical pyroptotic and osteoclastogenic fates of macrophages”
Gabriel Mbalaviele
Washington University, USA
11:00 am Coffee Break
11:30 am “Pathways inducing resolution of inflammatory bone loss”
Aline Bozec
University of Nuremberg-Erlangen, Germany
Short Talks
12:10 pm "Phosphatidylserine exposure and caspase activation regulate osteoclast fusion and bone homeostasis"
Brenda Krishnacoumar
Leibniz Institute for Analytical Sciences - ISAS, Germany
12:30 pm "Deletion of transferrin receptor 2 (Tfr2) promotes macrophage activation and aggravates inflammation in serum transfer-induced arthritis"
Maria G. Ledesma-Colunga
Department of Medicine III & Center for Healthy Aging, TU Dresden, Germany
12:50 pm "De novo steroidogenesis in tumor cells promotes osteoclastogenesis and bone metastasis formation"
David Gyori
Semmelweis University, Hungary
1:10 pm "Notch signal modulates phenotype and function of osteoclasts differentiated from common trilineage myeloid progenitor under inflammatory conditions"
Danka Grcevic
University of Zagreb, Croatia
1:30 pm "Longitudinal evaluation of Wnt inhibitors and comparison with others serum osteoimmunological biomarkers in osteolytic bone metastasis"
Emanuela Galliera
University of Milan, Italy
1:50 pm Lunch and Informal Discussion
7:30 pm Dinner and Informal Discussion
Tuesday May 17, 2022
8:00 am Breakfast
Chair: Lionel Ivashkiv/ Joseph Lorenzo
9:00 am: “Inflammatory regulation of bone and joint tissue repair”
Lionel Ivashkiv
Weill Cornell Medical College, USA
9:40 am “An osteoclast - S. aureus vicious cycle in osteomyelitis”
Deborah Veis
Washington University, USA
10:20 am: “Bone loss in inflammatory arthritis”
Iannis Adamopoulos
Harvard Medical School, USA
11:00 am Coffee Break
11:30 am “Inflammatory bone destruction- a translational view”
Georg Schett
University of Nuremberg-Erlangen, Germany
Short Talks
12:10 pm "Hematopoietic stem cell transplantation and its influence on the bone structure and marrow cells"
Radost Sass
Julius-Wolff Institut,Charité Universitätsmedizin Berlin, Germany
12:30 pm "Eosinophils control osteoclast-mediated bone loss via the secretion of eosinophil peroxidase"
Darja Andreev
University Erlangen-Nürnberg, Germany
12:50 pm "The availability of serine is critical for osteoclast differentiation"
Markus Kieler
Medical University of Vienna, Austria
1:10 pm "Maxillo-mandibular Osteoimmunology - Hidden Fatty Degeneration in Jawbone Marrow as Interface to Systemic Inflammation?"
Johann Lechner
Praxisklinik Integrative Dentistry, Germany
1:30 pm "Cellular Heterogeneity and Cell-Cell Communication of Multinucleated Giant Cell Precursors"
Melanie Hofmann
Medical University of Vienna, Austria
1:50 pm Lunch and Informal Discussion
3:30 pm City Tour
7:30 pm Dinner and Informal Discussion
Wed May 18, 2022
8:00 am Breakfast
Chair: Natalie Sims/Yongwon Choi
9:00 am: “MALPs: a master regulator of bone marrow environment”
Ling Qin
University of Pennsylvania, USA
9:40 am “New roles for G-CSF and neutrophils in controlling bone structure”
Natalie Sims
St. Vincent's Institute, Australia
10:20 am: “Studies of osteoclast lineage development in health and disease”
Joseph Lorenzo
University of Connecticut, USA
11:00 am Coffee Break
11:30 am “Identification of pathogenic tissue-resident macrophages visualized by intravital multiphoton imaging technology”
Masaru Ishii
Osaka University, Japan
Short Talks
12:10 pm "Mimicking S. aureus response with combinational synthetic TLR-agonists for MSC osteogenesis in vitro"
Paree Khokhani
University Medical Centre, Utrecht , Netherlands
12:30 pm "Regulatory T cells - the role of phenotypical properties during bone healing and regeneration"
Ann-Kathrin Mess
Julius Wolff Institute,Charité University Medicine Berlin, Germany
12:50 pm "Reduction of mature B cells and immunoglobulins results in increased trabecular bone"
Engdahl Cecilia
University of Gothenburg, Sweden
1:10 pm "ERa signaling in CXCL12-abundant reticular cells regulates trabecular bone in mice"
Julia Scheffler
University of Gothenburg, Sweden
1:30 pm "The influence of the early B cell protein lamda5 on bone homeostasis and aging"
Mohamed Khass
University of Alabama at Birmingham, USA
1:50 pm Lunch and Informal Discussion
8:00 pm Farewell Dinner
Thur May 19, 2022
8:00 am Breakfast
12:00 pm Departure