Among the topics to be covered at this meeting are:

• Hypoxia, migration and metastasis
• HIF-dependent pathways as therapeutic targets in oncology
• Tumor Metabolism
• Unfolded Protein Response and Integrated Stress Response
• Autophagy, and Apoptotic resistance and non-canonical cell death pathways
• Epigenetic regulation and non-coding RNAs in the TME
• Interactions between tumor, the immune system and stroma
• Neoangiogenesis/vasculogenesis-pathways and targets
• Influence of the TME in clinical modalities