5th International Conference on Model Hosts

Program

Saturday, September 28

     

7:00 PM

 

Conference Registration

     

8:00 PM

 

Welcome Dinner / Reception

     

Sunday, September 29

     

8:00 AM

 

Breakfast

     

8:55 AM

 

Welcome and Opening Remarks - Nathalie Pujol

     

SESSION I

 

Keynote Speaker

Chair: Arturo Casadevall

9:10 AM

1

Evolution of Fungal Pathogens

Joseph Heitman

     

SESSION II

 

Molecular traits at the host/microbe interface

Chair: Michael Gilmore

9:40 AM

2

Metabolic regulation of surface penetration by the non-motile pathogen Enterococcus faecalis 

Diana Morales

10:00 AM

3

CRISPR-Cas defense against conjugative antibiotic resistance plasmids in enterococci

Breck Duerkop and Kelli Palmer

10:20 AM

4

Identifying and developing antimicrobial compounds that target IMPDH

Shen Yu, Terence Moy, Rhonda Feinbaum, Laurence Rahme, Nathanial Sherden, Brent Cezairliyan, and Frederick Ausubel

10:40 AM

5

Using S. aureus gene expression data from human infections to inform experimental models

Marvin Whiteley

11:00 AM

6

Probing host-pathogen interactions with defined mucus models

Kelsey Wheeler, Gerardo Carcamo-Oyarce, Bradley Turner, Julia Co, Sylvain Lehoux, Sheri Dellos-Nolan, Richard Cummings, Daniel Wozniak, and Katharina Ribbeck

11:20 AM

7

Diversification of Enterococci as Host Habitats Evolve

Michael Gilmore and Ashlee Earl

11:40 AM

8

Galleria mellonella as a novel in vivo immune modulation platform

Vanessa Francis, Richard Titball, Olivia Champion, and Amy Housden

     

12:00 PM

 

Coffee Break

     

SESSION III

 

In vivo imaging of host response to infection

Chair: Nathalie Pujol

12:20 PM

9

Imaging different routes of pathogen neuroinvasion in zebrafish

Valerio Laghi, Emma Colucci, and Jean-Pierre Levraud

12:40 PM

10

C. elegans as a tractable host to study natural infections by oomycetes

Michael Fasseas, Manish Grover, Florence Drury, and Michalis Barkoulas

1:00 PM

11

Sensing damage in the C. elegans epidermis

Nathalie Pujol

1:20 PM

12

A toxin-antitoxin system modulates the virulence of Pseudomonas aeruginosa in its Drosophila host in distinct models of infection

Jing Chen, Guiying Lin, Zi Li, Xiaoxue Wang, Samuel Liegeois, and Dominique Ferrandon

1:40 PM

13

C. elegans microbiota-mediated protection from pathogen infection

Kohar Kissoyan and Katja Dierking

2:00 PM

14

The role of the bZIP transcription factor ZIP-1 in the intracellular pathogen response of C. elegans

Vladimir Lazetic, Fengting Wu, Lianne Cohen, Kirthi Reddy, and Emily Troemel

     

2:20 PM

 

Lunch and Informal Discussions

     

7:30 PM

 

Dinner and Informal Discussions

     

Monday, September 30

     

8:00 AM

 

Breakfast

     

SESSION IV

Insect Biotechnology

Chair: Andreas Vilcinskas

9:00 AM

15

Antimicrobial peptides of Galleria mellonella

Agnieszka Zdybicka-Barabas, Aneta Sowa-Jasilek, Sylwia Staczek, Katarzyna Grygorczuk-Planeta, Pawel Mak, Bożena Pawlikowska-Pawlega, Rafal Luchowski, Wieslaw Gruszecki, and Malgorzata Cytrynska

9:20 AM

16

Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella

Ivan Dubovskiy, Krishnendu Mukherjee, Ekaterina Grizanova, Rüdiger Lehmann, and Andreas Vilcinskas

9:40 AM

17

Biological pest control with insect pathogens

Kwang-Zin Lee, Tessa Carrau, Nils Hiebert, and Andreas Vilcinskas

10:00 AM

18

Galleria model for UPEC pathogenesis

Miriam Kalsy, André Billion, Ulrich Dobrindt, Andreas Vilcinskas, and Krishnendu Mukherjee

10:20 AM

19

Drosophila melanogaster as a model to study host-pathogen interactions in the context of nutrition

Anika Wagner

10:40 AM

20

Pathogens associated with invasive or introduced insects threaten the health and diversity of native species

Andreas Vilcinskas

     

11:00 AM

 

Coffee Break

     

SESSION V

 

Model hosts in drug and probiotic discovery and development

Chairs: Frederick M. Ausubel and Eleftherios Mylonakis

11:30 AM

21

Chemical screening for anti-infectives in zebrafish reveals a novel role for iGluRs in innate immunity

Anne Clatworthy, Margarita Parada-Kusz, Senya Combs, Jenny Lee, Susumu Tomita, and Deborah Hung

11:50 AM

22

Chemical dissection of host-microbe interactions

Howard Hang

12:10 PM

23

Neuronal OLRN-1 promotes intestinal immune homeostasis to ensure evolutionary fitness

Read Pukkila-Worley

12:30 PM

24

Membrane-targeting antimicrobial compounds with activity against persistent methicillin-resistant Staphylococcus aureus identified using a Caenorhabditis elegans infection screen

Eleftherios Mylonakis

12:50 PM

25

Targeting pyoverdine-dependent virulence in multidrug resistant clinical isolates of pseudomonas aeruginosa

Natalia Kirienko

1:10 PM

26

Indoles from commensal microbiota regulate healthspan

Daniel Kalman

     

1:30 PM

 

Lunch and Informal discussions

     

7:30 PM

 

Dinner and Informal Discussions

     

Tuesday, October 1

     

8:00 AM

 

Breakfast

     

SESSION VI

 

The diversity of host systems

Chair: Arturo Casadevall

9:00 AM

27

Accidental and paradoxical macrophage response to an amoeba host-adapted Legionella effector

Yousef Abu-Kwaik

9:20 AM

28

Microbiome as modulator: exploring virulence in the Drosophila melanogaster model

Nichole Broderick

9:40 AM

29

Low virulence Candida species induce trained innate immunity against polymicrobial sepsis with a diverse spectrum of activity

Paul Fidel and Mairi Noverr

10:00 AM

30

High fat diet induces microbiota-dependent silencing of enteroendocrine cells in zebrafish

John Rawls, Lihua Ye, Rodger Liddle, and Olaf Mueller

10:20 AM

31

Taking a Pythagorean View of Host-Microbe interactions.

Arturo Casadevall

     

10:40 AM

 

Coffee Break

     

SESSION VII

Roles of ROS in Host Response

Chairs: Danielle A. Garsin and Ransome van der Hoeven

11:10 AM

32

Nucleolar function in innate immunity

Adam Antebi

11:30 AM

33

NOX-ROS networks and intestinal disease

Ulla Knaus

11:50 AM

34

EntV, a bacteriocin, is a novel inhibitor of fungal virulence in multiple models

Michael Lorenz, Armand Brown, Carrie Graham, Yasmin Chebaro, Melissa Cruz, and Danielle Garsin

12:10 PM

35

Activation of immune and stress responses by mitis group streptococci

Ali Naji, Caroline Rog, Ali  Al Hatem, Patrick  Scholl, and Ransome van der Hoeven

12:30 PM

36

New Regulators of SKN-1/Nrf Identified in the Caenorhabditis elegans Infection Model

Ozgur Karakuzu and Danielle Garsin

     

12:40 PM

 

Lunch and Informal discussions

     

3:00 PM

 

City Tour

     

7:30 PM

 

Dinner and Informal Discussions

     

Wednesday, October 2

     

8:00 AM

 

Breakfast

     

SESSION VIII

Whole animal responses to microbial infections

Chair: Alejandro Aballay

9:00 AM

37

Neuronal control of epithelial host defense against enteric infection

Javier Irazoqui

9:20 AM

38

Cultivating relationships: host genetics shape microbiome form and function in C. elegans

Adrien Assié, Fan Zhang, Jessica L Weckhorst, and Buck S Samuel

9:40 AM

39

the octopaminergic immunoinhibitory pathway in C. elegans

Durai Sellegounder, Chung-Hsiang Yuan, Phillip Wibisono, Yiyong  Liu, and Jingru Sun

10:00 AM

40

Bacteria from the human microbiome differentially regulate neurodegeneration in C. elegans

Lesley MacNeil

10:20 AM

41

A novel role for CXCR2 in the mucosal response to microbes

Manuela Raffatellu

10:40 AM

42

Intestinal infection regulates behavior and learning via neuroendocrine signaling

Jogender Singh and Alejandro Aballay

     

11:00 AM

 

Coffee Break

     

SESSION IX

 

Novel insights from Model-Host Systems-II

Chair: Javier Irazoqui

11:20 AM

42

Resources and funding support provided by the US National Institute of Allergy and Infectious Diseases (NIAID/NIH)

Kentner Singleton

11:40 AM

43

A computational framework to evaluate bacterial infection models using transcriptomic data

Daniel Cornforth and Marvin Whiteley

12:00 PM

44

Importance of molecular motors in Salmonella virulence

Ziyan Fang, Stéphane Meresse, and Jean-Pierre Gorvel

12:20 PM

45

Insects as models to study the impact of antibiotics and microbiota therapies on the human gut microbiome: reducing the use of mammals in research

Harriet Gooch, Marjorie Labédan, Anthony Maxwell, and Lindsay Hall

12:40 PM

46

Exploring fungal virulence using C. elegans

Xing Zhang, Benjamin Harding, Shizue Omi, Jérôme Belougne, Nathalie Pujol, and Jonathan Ewbank

1:00 PM

47

Dystrophic changes in chronic inflammatory type IV collagen col4a1 Drosophila mutants

Nikoletta Somlyai-Popovics, Andras A. Kiss, Zsolt Boldogkoi, Matyas Mink

1:20 PM

48

Drosophila melanogaster-based evaluation of phage therapy against Pseudomonas aeruginosa

You-Hee Cho

1:40 PM

49

Primary innate immune system activation in temperature-sensitive col4a1 Drosophila melanogaster mutants A. A. Kiss Institute of Medical Biology, University of Szeged, Somogyi B. u. 4, H-6720 Szeged, Hungary

András Kiss

     

2:00 PM

 

Closing Remarks

     

2:05 PM

 

Lunch and Informal discussions

     

8:00 PM

 

Farewell Dinner

     

Thursday, October 3

8:00 AM

 

Breakfast

     
   

Departure