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Thursday, October 03 |
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6:00 PM |
Conference Registration |
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8:00 PM |
Welcome Reception / Dinner |
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Friday, October 04 |
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SESSION I |
ORGANOGENESIS (Chairs- Jefferey Dilworth and Jette Lengefeld) |
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8:30 AM |
1 |
The molecular and signalling foundation of human naïve pluripotency Jacob Hanna |
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8:55 AM |
2 |
Safe and Allo-accepted Pluripotent Stem Cell Line: A Global Source for Off-the-Shelf Therapeutic Cell Products Andras Nagy |
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9:20 AM |
3 |
Making blood before a blood stem cell Jackie Lillis, Kate Fegan, Kathleen McGrath, and James Palis |
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9:55 AM |
4 |
Renewal and plasticity in oral epithelia Ophir Klein |
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10:20 AM |
5 |
Antagonism between Young and Old transposable elements mediates intra-organism selection in the early human embryo Manvendra Singh… and Zsuzsanna Izsvák |
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10:45 AM |
Coffee Break and Poster Viewing |
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11:30 AM |
6 |
Single-cell phenotyping reveals heterogeneity among macrophage precursors during embryogenesis Elvira Mass … and Frederic Geissmann |
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11:45 AM |
7 |
MAPK/ERK activity regulates kidney size and nephron number via multiple cellular functions Anneliis Ihermann-Hella… and Satu Kuure |
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SESSION III |
AGING (Chairs Claudia Waskow and Antonio del Sol) |
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12:00 PM |
8 |
B. |
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12:25 PM |
9 |
Dietary control of stem cells in physiology and disease Omer Yilmaz |
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12:50 PM |
10 |
Understanding muscle stem cell aging Pura Muñoz-Cánoves |
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1:15 PM |
11 |
Cell size determines stem cell potential during aging Jette Lengefeld |
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1:30 PM |
12 |
Aging-associated decline of energy metabolism limits rejuvenation potential of metformin treatment. Espada Lilia… and Maria Ermolaeva |
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1:55 PM |
Lunch and Informal Discussions |
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Saturday, October 05 |
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SESSION IV |
Hematopoietic Stem Cells (Chairs Marjorie Brand and Elvira Mass) |
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8:30 AM |
13 |
Regulation of dormant hematopoietic stem cells Nina Cabezas-Wallscheid |
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8:55 AM |
14 |
Translational control in the regulation of hematopoietic stem cell fate and function Kristin Hope |
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9:20 AM |
15 |
New Insights from Experimental Models of De Novo Human Leukemogenesis Connie Eaves |
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9:45 AM |
16 |
Hematopoietic stem cell response to acute thrombocytopenia requires signaling through distinct receptor tyrosine kinases Beáta Ramasz… and Tatyana Grinenko |
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10:00 AM |
17 |
Absolute quantification of transcription factors in human erythropoiesis reveals principles of transcriptional regulation Marjorie Brand |
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10:25 AM |
18 |
Enhancing hematopoiesis from embryonic stem cells through MLL1-induced activation of a Rac/Rho/integrin signaling axis Patricia Ernst |
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10:50 AM |
Coffee Break |
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SESSION V |
Stem Cell Niche (Chairs – Jefferey Dilworth and Tatyana Grinenko) |
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11:20 AM |
19 |
Pathophysiology of muscle stem cell environment Bénédicte Chazaud |
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11:45 AM |
20 |
Dlp-Mediated Hh and Wnt Signaling Interdependence Is Critical in the Niche for Germline Stem Cell Progeny Differentiation Renjun Tu, Bo Duan, Xiaoqing Song, and Ting Xie |
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12:10 PM |
21 |
Regulation of the mouse skeletal muscle stem cell niche during homestasis and regeneration Shahragim Tajbakhsh |
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12:35 PM |
22 |
Embryonic origin of osteoclasts Gulce Percin… and Claudia Waskow |
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12:50 PM |
23 |
A functional niche for hematopoietic stem cells from mice and human Claudia Waskow |
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Sunday, October 06 |
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SESSION VI |
Neural Stem Cells (Chairs - Marjorie Brand and Laura Kerosuo) |
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8:30 AM |
26 |
SWI/SNF complex control of neural progenitor cell differentiation Fangjian Gao… and Diana Hargreaves |
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8:55 AM |
27 |
Sex and age dependent activation of resident neural precursor cells to promote self-repair of the injured nervous system. Cindi Morshead |
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9:20 AM |
28 |
Efficacy of Human iPSC-derived Interneuron Precursor Cell Grafts for Alleviating Spontaneous Seizures and Related Co-morbidities in a Model of Chronic Temporal Lobe Epilepsy Ashok Shetty… and Su-Chun Zhang |
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9:35 AM |
29 |
Neurog2 and Ascl1 co-expression defines a population of Notch ligand-expressing niche cells that control the timing of embryonic cortical neurogenesis Sisu Han, … and Carol Schuurmans |
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10:00 AM |
30 |
Human brain organoid models of neural development and disease Jenny Hsieh |
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10:25 AM |
31 |
Multiple roles of Fibro/Adipogenic progenitors in homeostasis and regeneration Fabio Rossi.. and Chihkai Chang |
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10:50 AM |
Coffee Break and Poster Viewing |
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SESSION VII |
iPS cells (Chairs - Ondine Cleaver and Satu Kuure) |
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11:45 AM |
32 |
TBD Ondine Cleaver |
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12:10 PM |
33 |
A chromatin-focused CRISPR screen identifies SETD2, a Histone H3K36 methyltransferase, as a barrier to human somatic cell reprogramming Burcu Özçimen, …and Tamer Onder |
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12:25 PM |
34 |
Self-organisation of the mouse and human embryo Magdalena Zernicka-Goetz |
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12:50 PM 1:05 PM |
35 |
Single cell-based computational approach for subpopulation cellular conversion Antonio del Sol Dissecting the formation and maintenance of the neural crest stem cell niche |
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1:20 PM |
37 |
Induced pluripotent stem cell derived basal cells provide a novel source of multi lineage airway epithelial cells Amy Ryan (Firth)… and Jinghui Gao |
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1:30 PM |
38 |
Direct reprogramming of iPSCs into glutamatergic neurons: Reconstruction of transcriptional events and integration of epigenetic changes Muhammad Kaiser Abdul Karim… and Mark Kotter |
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1:45 PM |
Lunch and Informal Discussions |
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3:30 PM |
City Tour |
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7:30 PM |
Dinner and Informal Discussions |
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Monday, October 07 |
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SESSION VIII |
Disease (Chairs Gulce Percin and Dan Robinson) |
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8:30 AM |
39 |
Using stem cells to uncover the molecular pathophysiological mechanisms underlying complex neurological disorders Evan Snyder |
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8:55 AM |
40 |
Gene correction of LGMD2A patient-specific iPS cells for targeted autologous cell therapy Rita Perlingeiro |
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9:20 AM |
41 |
Stem cell-based modelling of complex diseases Agota Apati |
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9:45 AM |
42 |
Gene Editing of Cystic Fibrosis Airway Basal Stem Cells Shingo Suzuki… and Brian Davis |
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10:00 AM |
43 |
Dysregulation of the epithelial stem cell factor p63 initiates the development of Sjögren’s syndrome Filipa Pinto… and Makoto Senoo |
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10:15 AM 10:30 AM |
Business Meeting Coffee Break and Poster Viewing |
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SESSION IX |
Muscle Regeneration (Chairs Julia von Maltzhan. and Marc Kotter) |
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11:25 AM |
44 |
Two Critical Checkpoints During Early Activation of Adult Muscle Satellite Cells Zhenguo Wu |
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11:50 AM |
45 |
Metabolites Regulating Muscle Stem Cell Biology Vittorio Sartorelli |
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12:15 PM |
46 |
Dynamics of muscle stem cells during tissue growth and regeneration MJ Stec… and Alessandra Saccoa |
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12:40 PM |
47 |
Fibroadipogenic progenitors in a mouse model for facioscapulohumeral muscular dystrophy Michael Kyba |
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1:05 PM |
48 |
Maturation of hiPSC-derived cardiac cell types Laurie Boyer |
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1:30 PM |
49 |
Promoter-proximal stalling of RNA-Polymerase II is required for repopulation of the satellite cell niche after muscle injury. F. Jeffrey Dilworth |
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1:55 PM |
Closing Remarks – Kursad Turksen |
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2:15 PM |
Lunch and Informal Discussions |
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8:00 PM |
Farewell Dinner |
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Tuesday, October 08 |
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8:00 AM |
Breakfast |
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10:00 AM |
Departure |
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POSTERS |
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51 |
Generation and characterization of MafA-GFP reporter lines in a induced pluripotent stem cells background for Islet cell research. SHAILESH GUPTA, Christian Honoré, Björn Magnusson, Marcello Maresca, Ryan Hicks, and Jacob Sjölin |
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52 |
Fgf and Wnt signaling pathways intersect in the mesenchymal niche of the hair follicle to regulate the hair cycle clock Sarina Harshuk-Shabso, Hila Dressler, Emil Aamar, and David Enshell-Seijffers |
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53 |
An Engineered Multicellular Stem Cell Niche for the 3D Derivation of Human Myogenic Progenitors from iPSCs Omid Mashinchian |
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54 |
Autologous mesenchymal/stromal stem cells therapy modulates immune response in multiple sclerosis patients Maryna Zafranskaya, Alexander Fedulov, Alexei Borisov, Mariya Yurkevich, Svetlana Krivenko, and Darya Nizheharodava |
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55 |
Multipotent mesenchymal stromal cells migration on rotenone-induced rat model of Parkinson's disease Darya Nizheharodava, Natallia Aleinikava, Tatsiana Kuznetsova, Marharyta Vanslau, Alexandr Boika, Tatsiana Ihnatovich, Vladimir Ponomarev, and Maryna Zafranskaya |
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56 |
Expression of Fibrogenesis Markers after Mesenchymal Stem Cell Therapy for Experimental Liver Cirrhosis and Acute Kidney Injury Maryna Zafranskaya, Tatsiana Ihnatovich, Mikalai Halabarodzka, Tatsiana Savitskaya, and Darya Nizheharodava |
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57 |
Treatment with human induced pluripotent stem cell-derived neural precursors has a beneficial effect on changes in metabolic spectra after focal brain ischemia in rats. Nataliya Romanyuk, Daniel Jirak, Natalia Ziolkowska, Karolina Turnovcova, Kristyna Karova, and Pavla Jendelova |
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58 |
Early erythroid differentiation is closely associated with the progression through S phase Petr Páral, Martin Báječný, Tomáš Heizer, Luděk Šefc, and Emanuel Nečas |
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59 |
Lack of evidence for active role of hematopoietic stem cells in intensive bone marrow regeneration Kateřina Faltusová, Tomáš Heizer, Martin Báječný, and Emanuel Nečas |
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60 |
Lin-Sca-1+c-Kit+ (LSK) cells are altered myeloid progenitors in regenerating bone marrow Emanuel Nečas, Kateřina Faltusová, Chia-Ling Chen, Martin Báječný, Tomáš Heizer, Petr Páral, and Filipp Savvulidi |
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61 |
Human mesenchymal stromal cells derived from different tissues as sources for cell and cell-free therapy, with a focus on neuroregenerative potential Irena Vackova, Milada Chudickova, Yuriy Petrenko, Karolina Turnovcova, Kristyna Kekulova, and Sarka Kubinova |
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62 |
Neural differentiation and gene expression of human amniotic fluid stem cells derived from healthy and foetus Down syndrome pregnancies Aistė Zentelytė, Deimantė Žukauskaitė, Veronika Borutinskaitė, and Rūta Navakauskienė |
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63 |
In vitro modelling of cardiac differentiation in DiGeorge syndrome Tünde Berecz, Andrea Molnár, Brigitta Szabó, Irén Haltrich, László Homolya, Sian Harding, János Réthelyi, Béla Merkely, Gábor Földes, and Ágota Apáti |
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64 |
MGF and IGF-I have a neuroprotective effect at high glucose concentrations during the time of injury by increasing the proliferation of NSCs Tuğba Gürbüz, Selçuk Sözer Tokdemir, Burcu Sarya Tunç, and Kenan Ateş |
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65 |
Dissecting the formation and maintenance of the neural crest stem cell niche Laura Kerosuo, Ceren Pajanoja, Jenny Hsin, and Andrew Schiffmacher |
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66 |
Programming cell identity: Enabling the next generation of human cell models Tüzer Kalkan, Thomas Moreau, Imbisaat Geti, Michael D'Angelo, Fabian Bachinger, Patrick Rericha, Giacomo Borsari, and Mark Kotter |
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67 |
Stimulation of Human skin derived mesenchymal stromal cell proliferation using a herbal distillate: a pilot study Praneeth Ratnayake, Udaya Samaratunga, Jayamini Seneviratne, and Preethi Udagama |
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68 |
New molecular and cellular insights into the myovascular niche of skeletal muscle satellite cells: role of the sympathetic innervation Alessio Rotini, Juliette Berthier, Romain Gherardi, Frederic Relaix, and Peggy Lafuste |
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69 |
Deciphering the role of human-specific genes in the development of the human neocortex Fabio Marsoner, Ammar Jabali, Elina Nürnberg, Miriam Wandres, Andrea Rossetti, Thorsten Lau, Mathias Hafner, Philipp Koch, and Julia Ladewig |
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70 |
aberrant splicing of the stem cell factor p63 increases susceptibility to tumorigenesis in epithelia Keshia Pitt, Filipa Pinto, and Makoto Senoo |
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71 |
Generation of Lacrimal Gland from Induced Pluripotent Stem Cells Sinan Guven, Melis Asal, and Canan Yildirim |
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72 |
Deciphering the role of Neurog2-Ascl1 co-expression in the retina Yacine Touahri, Sisu han, Jiayi Zhao, Hibo Rijal, Matthew Brooks, Anand Swaroop, and Carol Schuurmans |
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73 |
Treatment efficacy of human amniotic stem cells for the kidney damages in type 2 diabetic nephropathy Xue-Yuan Bai |
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74 |
Human mesenchymal stem cell-derived extracellular vesicles attenuate inflammation evoked by focal brain injury in rats Barbara Lukomska, Sylwia Dabrowska, Anna Andrzejewska, and Miroslaw Janowski |