2nd International Conference on the Long and the Short of Non-Coding RNAs

Program

Friday, June 9

     

6:00 PM

 

Conference Registration

     

8:00 PM

 

Welcome Reception and Dinner

     

Saturday, June 10

     

7:30 AM

 

Breakfast

     

8:25 AM

 

Welcome and Opening Remarks

     

SESSION I

 

Systems biology of ncRNAs

Chair: Howard Chang

8:30 AM

1

Genome regulation by long noncoding RNAs

Howard Chang

9:00 AM

2

Truncated proteins generated from intronic polyadenylation inactivate tumor suppressor genes

Christine Mayr

9:30 AM

3

A new role for Argonaute phosphorylation in microRNA-mediated silencing

Joshua Mendell

10:00 AM

4

New evidence for Piwi association with specific sites in the Drosophila genome

Nils Neuenkirchen, Na Liu, Mei Zhong, and Haifan Lin

10:15 AM

5

Noncanonical function of DGCR8 controls mESC exit from pluripotency

Daniel Cirera-Salinas

10:30 AM

6

Deciphering target-induced miRNA degradation

Paulina Pawlica and Joan Steitz

     

10:45 AM

 

Coffee Break and Poster Session

     

SESSION II

 

microRNA biogenesis and regulation

Chair: David Bartel

11:45 AM

7

MicroRNAs and mRNAs

David Bartel

12:15 PM

8

RNA regulation in stem cells and disease

Richard Gregory

12:45 PM

9

Tudor-SN-mediated endonucleolytic decay of human-cell microRNAs promotes G1/S phase transition

Lynne Maquat

1:15 PM

10

Endogenous transcripts control miRNA levels and activity in mammalian cells by a target-induced miRNA degradation mechanism (TIMD)

Francesco Ghini, Matteo Marzi, and Francesco Nicassio

1:30 PM

11

A nucleoplasmic post-transcriptional control of microRNA-mediated silencing

Silvia Bottini, Emanuela Repetto, and Michele Trabucchi

1:45 PM

12

Functional complicity of the oncogene, CSDE1 at multiple layers of miRNA mediated gene regulation 

Pavan Kumar Kakumani and Martin Simard

     

2:00 PM

 

Lunch and Informal Discussions

     

7:30 PM

 

Dinner and Informal Discussions

Buses depart from the hotel lobby at 7:30 PM

     

Sunday, June 11

     

7:30 AM

 

Breakfast

     

SESSION III

Genome editing and RNA therapeutics

Chair: Beverly Davidson 

8:30 AM

13

Advancing therapies for dominant neurogenetic diseases

Beverly Davidson

9:00 AM

14

Cancer modeling in the CRISPR age

Andrea Ventura

9:30 AM

15

Knocking out a circRNA in mouse and reconstructing an embryo from single-cell sequencing data

Nikolaus Rajewsky

10:00 AM

16

An Arabidopsis circRNA regulates splicing of its cognate mRNA through R-loop formation

Vanessa Conn, Veronique Hugouvieux, Aditya Nayak, Stephanie Conos, Giovanna Capovilla, Gokhan Cildir, Agnes Jourdain, Vinay Tergaonkar, Markus Schmid, Chloe Zubieta, and Simon Conn

10:15 AM

17

Analysis of circular RNAs biogenesis and function in neuronal and skeletal muscle cells

Mariangela Morlando, Lorenzo Errichelli, Stefano Dini Modilgiani, Ivano Legnini, Gaia Di Timoteo, Rebecca Scarfò, Francesca Rossi, Alessio Colantoni, Pietro Laneve, Davide Capauto, and Irene Bozzoni

10:30 AM

18

Remodelling the spliceosome for therapy using modified U1 core spliceosomal RNA particles

Franco Pagani

     

10:45 AM

 

Coffee Break and Poster Session

     

SESSION IV

mRNA metabolism 1

Chair: Javier Caceres

11:45 AM

19

Global biological consequences of the regulation of Alternative splicing by Pol II elongation rate

Javier Caceres

12:15 PM

20

Alternative splicing and immune responses

Matthew Thompson and Kristen Lynch

12:45 PM

21

Alternative lifestyles of messenger RNAs

Andrei Thomas-Tikhonenko

1:15 PM

22

Regulation of translation initiation by miRNAs and RNA-binding proteins

Daniel Peter, Ramona Weber, Dipankar Bhandari, Lara Wohlbold, Eugene Valkov, Oliver Weichenrieder, Cátia  Igreja, and Elisa Izaurralde

     

1:45 PM

 

Lunch and Informal Discussions

3:00 PM  

SPECIAL SESSION: Meet the Editors

Anke Sparmann (Nature Structural & Molecular Biology)
Anne Nielsen (EMBO Journal)
Andrew Cosgrove (Genome Biology)
Sabi Lall (Cell Reports)

 

7:30 PM

 

Dinner and Informal Discussions

Buses depart from the hotel lobby at 7:30 PM

     

Monday, June 12

     

7:30 AM

 

Breakfast

     

SESSION V

 

lncRNAs in development & disease

Chair: David Corey

8:30 AM

23

The nucleus as a target for controlling expression by duplex RNAs

David Corey

9:00 AM

24

Elucidating the functions of the non-coding genome

Reuven Agami

9:30 AM

25

DNA:RNA triple helices guide lncRNAs to specific genomic loci

Ingrid Grummt

10:00 AM

26

lncRNA Meg3 choreographs the epigenetic landscape of postmitotic motor neuron cell fate and subtype identity

Ya-Ping Yen and Jun-An Chen

10:15 AM

27

Tumor-associated macrophages enhance glycolysis of Breast cancer via exosome-transmitted LncRNA

Chen Fei, Su Shicheng, and Song Erwei

10:30 AM

28

A long non-coding RNA modulate alternative splicing in plants

Natali Romero-Barrios, Federico Ariel, Aurélie Christ, Celine Charon, Daniel Gautheret, Thomas Blein, and Martin Crespi

     

10:45 AM

 

Coffee Break and Poster Session

     

SESSION VI

mRNA metabolism 2

Chair: Judy Lieberman

11:45 AM

29

RNA methylation in gene expression regulation

Chuan He

12:15 PM

30

Shooting the messenger: Rapid and global mRNA decay in apoptosis

Judy Lieberman

12:45 PM

31

Hidden lifestyles of messenger RNAs

Zissimos Mourelatos

1:15 PM

32

Regulation of transcription by microRNAs in lupus

Marianthi Kiriakidou

     

1:45 PM

 

Lunch and Informal Discussions

     

3:15 PM

 

City Tour

Buses depart from hotel lobby at 3:30 PM

     

7:30 PM

 

Dinner and Informal Discussions

Please note buses do not pick-up at the hotel prior to dinner.

Dinner proceeds right after the tour.

     

Tuesday, June 13

     

7:30 AM

 

Breakfast

     

SESSION VII

Long and short ncRNAs in cancer

Chair: Iannis Aifantis

8:30 AM

33

Diverse roles for novel lncRNAs in acute leukemia initiation and progression

Iannis Aifantis

9:00 AM

34

A miR-200-Quaking regulatory pathway coordinates widespread alternative splicing changes during EMT

Gregory Goodall

9:30 AM

35

Cancer cell addiction to lncRNAs

Chris Marine

10:00 AM

36

SAMMSON coordinates ribosome and mitoribosome biogenesis to promote tumor growth

Eleonora Leucci

10:15 AM

37

The long noncoding RNA KTN1-AS1 regulates B-cell lymphoma proliferation as an important downstream effector of c-MYC

Melanie Winkle, Agnieszka Dzikiewicz-Krawczyk, Niu Fubiao, Debora de Jong, Jasper Koerts, Klaas Kok, Anke van den Berg, and Joost Kluiver

10:30 AM

38

Investigating the oncogenic role of NONO RNA-binding protein binding to lncRNA NEAT1_v2 in high-risk neuroblastoma

Alina Naveed, Ruohan Li , Sue  Fletcher, Steve Wilton, Simon Kobelke, Jack Cooper, Charles Bond, Alistair Forrest, Tao Liu, and Archa Fox

     

10:45 AM

 

Coffee Break and Poster Session

     

SESSION VIII

Short RNAs in development & disease

Chair:  Martine Simonelig

11:45 AM

39

mRNA regulation by piRNAs and PIWI proteins in Drosophila

Martine Simonelig

12:15 PM

40

The miR-290/302 miRNA clusters regulate the timing of cellular differentiation and phasing of genes in the cell cycle

Robert Blelloch

12:45 PM

41

miR-34/449 miRNAs in ciliogenesis

Rui Song and Lin He

1:15 PM 43

FolamiRs: vehicle-free delivery of therapeutically relevant microRNAs 

Andrea Kasinski, Philip Low, Esteban Orellana, Loganathan Rangasamy, and Srinivasa Tenneti

     

1:40 PM

 

Closing Remarks

     

1:45 PM

 

Lunch and Informal Discussions

     

8:00 PM

 

Farewell Dinner

     
       

Wednesday, June 14

     

8:00 AM

 

Breakfast

10:00 AM

 

Departure


POSTERS

44

miR-200b targets actin cytoskeleton regulators and inhibits triple negative breast cancer metastasis

Chengfeng Yang, Brock Humphries, Yunfei Li, and Zhishan Wang

45

Autophagy mediated AUDLA1 lncRNA degradation promotes breast cancer metastasis

Chang Gong, Xin Jin, and Erwei Song

46

The emerging role of microRNAs in fetal alcohol spectrum disorders

Xiaopan Chen, Jie Liu, and Shao-yu Chen

47

The screening and identification of non-coding RNA related to the radioresistance of nasopharyngeal carcinoma

Yuanzheng Qiu, Yong Liu, Guo Li, Chao Liu, Shuling Ren, and Donghai Huang

48

Profiling of circular RNAs in postmortem brains and induced pluripotent stem cell-derived neuronal cultures from subjects with psychiatric disorders

Nikolaos Mellios, Jason Weick, Brian Rodriguez, Alexander Hafez, Brigham Hartley, Kristen Brennand, Stephen Haggarty, and Nora Perrone-Bizzozero

49

microRNA-223 suppresses inflammation by down regulating NF-kB activation in epithelial cells

Qing Deng

50

non coding RNAs as radiation dosimetry biomarkers for radiation injury

Moly Aryankalayil, Adeola Makinde, Iris Eke, Joel Levin, Uma Shankavaram, and Norman Coleman

51

lncRNA/DNA binding analysis reveals losses and gains and lineage specificity of genomic imprinting in mammals

Hao Zhu

52

microRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord 

Jun-An Chen

53

NKILA lncRNA promotes AICD of tumor-specific CTLs in breast cancer and contributes to tumor immune evasion

Di Huang, Shicheng Su, and Erwei Song

54

cis-acting complex-trait-associated lincRNA expression correlates with modulation of chromosomal architecture

Jennifer Tan, Adam Alexander Smith, Maria Ferreira da Silva, Cyril Matthey-Doret, Rico Rueedi, Reyhan Sönmez, David Ding, Zoltán  Kutalik, Sven Bergmann, and Ana Marques

55

OTP-AS1 is a new long noncoding RNA expressed specifically in many tumors

Yuliya Karnaukhova, Dmitry Polev, Larisa Krukovskaya , Andrey Makashov, and Andrey Kozlov

56

Therapeutic applications of SAMMSON lncRNA inhibition in uveal melanoma

Shanna Dewaele, Katrien Vanderheyden, Jo Vandesompele, and Pieter Mestdagh

57

long non-coding RNA PICSAR regulates expression of alpha2beta1 and alpha5beta1 integrins and migration of squamous carcinoma cells

Minna Piipponen, Jyrki Heino, Veli-Matti Kähäri, and Liisa Nissinen

58

microRNA sponges: High-throughput approach for in silico design and testing.

Tomas Barta, Lucie Peskova, and Ales Hampl

59

The altered microRNA expression profile of human cartilage endplate chondrocytes induced by intermittent cyclic mechanical tension

Xin Fan, Chencheng Feng, Minghan Liu, Minghui Yang, and Huan Liu

60

microRNAs as bile-based biomarkers in pancreatic biliary-tract cancers

Mireia Mato Prado, Adam Frampton, Niccola Funel, Elena Lopez-Jimenez, Leandro Castellano, Laura Meijer, Geert Kazemier, Long Jiao, Justin Stebbing, Elisa Giovannetti, and Jonathan Krell

61

A computational approach for identification of protein-RNA interactions uncovers direct binders of Xist lncRNA

Davide Cirillo

62

Improved expression of recombinant proteins from mammalian cells by utilizing non-coding RNAs: microRNA and siRNA           

Joseph Shiloach, Su Xiao, Eugene Buehler,Michael Betenbaugh, Myung Hee Park, and Scott Martin

63

Role of selective regulation of non-coding RNA by mammalian mRNA export complex TREX-2

Mayuko Shimoda, Kazuhiko Maeda, Shailendra Singh, Shizuo Akira, and Nobuo Sakaguchi

64

Role of long non-coding RNAs in ovarian teratocarcinoma

Sohini Chakraborty, Aritra Deb, and Zhumur Ghosh

65

UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq

Zhifu Sun, Asha Nair, Xianfeng Chen, Naresh Prodduturi, Junwen Wang, and Jean-Pierre Kocher

66

miRNA functions in single cells

Marcel Sauerbier, Sebastian Mackowiak, João Frade, Silvina Catuara, Luis Zapata Ortiz, Diego Bárcena Menéndez, Wenjing Kang, Simone Picelli, and Marc Friedländer

67

Elucidating BAP1-microRNA regulatory networks in models of BAP1-deficient mesothelioma

Zohra Butt, Jenna Kenyani, Joseph Sacco, and Judy Coulson

68

Splicing controls the ubiquitin response during DNA double-strand break repair

Chiara Pederiva, Stefanie  Böhm, and Marianne Farnebo

69

miRNA-mediated KHSRP silencing rewires distinct post-transcriptional programs during TGF-B-Induced Epithelial-to-Mesenchymal Transition

Margherita Puppo, Martina Rossi, Gabriele Bucci, Arfa Moshiri, Paola Briata, and Roberto Gherzi

70

A lincRNA Trincr1 represses FGF/ERK signaling and promotes the self-renewal of embryonic stem cells

Yangming Wang

71

NEAT1 drives metastatic program in prostate cancer

Dimple Chakravarty, Sujit Nair, and Mark Rubin

72

Microarray study of circulating mirna in blood plasma of lung cancer patients

Zaporozhchenko Zaporozhchenko, Evgeny Morozkin, Anastasia Ponomaryova, Nadezhda Cherdyntseva, Valentin Vlassov, and Pavel Laktionov

73

Characterization of miR-21 expression in locally invasive colon cancer cells

Boye Nielsen, Kirsten Knudsen, Jan Lindebjerg, Alexandra Kalmár, Béla Molnár, Flemming Sørensen, and Torben Hansen

74

The (lnc)RNA landscape of human αβ and γδ T cell development.

Matthias De Decker, Juliette Roels, Marieke Lavaert, Wouter Van Loocke, Pieter Van Vlierberghe, and Tom Taghon

75

PTENpg1 antisense RNA mediates PTEN suppression in vemurafenib resistance and predicts clinical outcome in melanoma patients

Linda Vidarsdottir, Alireza Azimi, Christian  Ingvar, Göran  Jönsson, Håkan Olsson, Johan Hansson , Marianne Frostvik Stolt, Dan Grandér, and Per Johnsson

76

Master and servant - The complex interplay of a long non coding RNA and its transcription factor

Stefanie Binder, Ivonne Zipfel, Tilo Buschmann, Kristin Reiche, and Friedemann Horn

77

The long non coding RNA STAiR18 and its pathophysiological role in glioblastoma cell invasion

Ivonne Zipfel, Stefanie Binder, and Friedemann Horn

78

Liquid biopsy - Non coding RNAs isolated from extracellular vesicles offer great potential as highly specific tools for cancer diagnostics and prognostics

Stefanie Ende, Stefanie Binder, and Friedemann Horn

79

JANOMIA - a java application for characterization non-miRNA reads in small RNA sequencing data

Xiangfu Zhong, Fatima Heinicke, Benedicte Lie, and Simon Rayner

80

piRNA biogenesis in testicular germ cells tumors

Sofia Kondratieva, Ildar  Gainetdinov, Yulia  Skvortsova, and Tatyana  Azhikina

81

microRNA induced by DNA damage response regulate the expression of FOXP1 and therapy response in CLL

Katerina Cerna, Jan Oppelt, Vaclav Seda, Katerina Musilova, Gabriela Pavlasova, Veronika Svobodova, Jiri Mayer, Sarka Pospisilova, and Marek Mraz

82

Down-regulated miRNAs in papillary thyroid cancer open new treatment and diagnostic perspectives

Manuel Saiselet, Alice Augenlicht, Marie Quiriny, Maxime Tarabichi, David Gacquer, Vincent Detours, Guy Andry, and Carine Maenhaut

83

Identification of apoptomiRs and associated target gene regulatory networks to propose new tailored therapy for ovarian carcinoma

Mégane Vernon, Matthieu Meryet-Figuière, Bernard Lambert, Emilie  Brotin, Nicolas Vigneron, Pascal Gauduchon, Laurent Poulain, and Christophe Denoyelle

84

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in colorectal cancer cells by binding to Matrin 3

Ashish lal and Ritu Chaudhary

85

Characterization of Notch-dependent mRNAs and miRNAs that control human TCR-gamma/delta T cell development

Anne-Catherine Dolens, Kaat Durinck, Joni Van der Meulen, Inge Van de Walle, Katrien De Mulder, Pieter-Jan Volders, Jelle De Medts, Peter  Pipelers, Katleen De Preter, Annelynn Wallaert, Gert Van Peer, Nadine Van Roy, Bruce  Poppe, Maté Ongenaert, Jo Vandesompele, Olivier  Thas, Pieter Rondou, Pieter Mestdagh, Pieter Van Vlierberghe, Frank Speleman, and Tom Taghon

86

miR-214 and miR-34a activate TP53 but suppress the expression of RELA, CTNNB1 and STAT3 in human cervical and colorectal cancer cells

Devarajan Karunagaran, Karthik Chandrasekaran, and Anusha Sathyanarayanan

87

Identification of functional lncRNAs involved in melanoma progression and metastasis by CRISPR screening

Jochen Imig, Andreas Kloetgen, Kathryn Hockemeyer, Yixiao Gong, Palaniraja Thandapani, Nikos Kourtis, Eric Wang, Aristotelis Tsirigos, Eva  Hernando, and Iannis Aifantis

88

Differential expression of long non-coding RNA GAS5 in post-traumatic stress disorder

Guia Guffanti, Aliza Wingo, Tanja Jovanovic, Charles Nemeroff, Amanda  Myers, and Kerry Ressler

89

Fast identification of statistically significant lncRNA-RNA interactions in a transcriptome-wide search

Ivan Antonov, Andrey Marakhonov, Maria Zamkova, Mikhail Skoblov, and Yulia Medvedeva

90

The role of the long non-coding RNA WiNTRLINC1 in homeostasis and carcinogenesis

Pantelis Hatzis

91

DeepLearning-based miRNA target prediction through whole mature miRNA analysis

Albert Pla Planas, Xiangfu Zhong, Fatima Heinicke, and Simon Rayner

92

DPF-3, dipeptidyl peptidase activity in the miRNA pathway

Rajani Gudipati, Sarah Carl, Kathrin Kunzer, Daniel Hess, Jan Seebacher, Iskra Katic, and Helge Grosshans

93

lncRNA regulation of Th17 development

Marcin Mycko, Alexander Dobin, Maria Cichalewska, Hanna Cwiklinska, Thomas Gingeras, and Krzysztof Selmaj

94

Control of cell division by long noncoding RNAs

Lovorka Stojic

95

Toward the absolute quantification of Cryptococcus neoformans small RNAs

Shannon Fullbrook, Kate Reddington, and Thomas Barry

96

Identification of a miRNAs family involved in mammary stem cells regulation

Chiara Tordonato, Matteo Marzi, Francesco Nicassio, and Pier Paolo Di Fiore

97

Down-regulation of circulating microRNA-223 in patients with Alzheimer’s disease or mild cognitive impairment

Roberta Mancuso, Simone Agostini, Ambra Hernis, Raffaello Nemni, and Mario Clerici

98

lncRNAs: emerging players in CFTR gene regulation

Jessica Varilh, Alexandra Pommier, Michel Koenig, Mireille Claustres, and Magali Taulan-Cadars

99

Long non-coding RNAs (lncRNAs) and stem cells properties in breast cancer

Matteo Marzi, Chiara Tordonato, Ines Simeone, Pier Paolo Di Fiore, and Francesco Nicassio

100

miRNA profiling identifies a RNA-BP as a novel CF regulator

Alexandra Pommier, Jessica Varilh, Michel Koenig, Mireille Claustres, and Magali Taulan-Cadars

101

Increased BACE1-AS long noncoding RNA and β-amyloid levels in ischemic heart failure

Simona Greco, Germana Zaccagnini, Paola Fuschi, Lorenzo Menicanti, and Fabio Martelli

102

Multifunctional nanoparticles delivering non-coding RNAs for triple negative breast cancer therapy

Nadia Ayat, Amita Vaidya, Zhanhu Sun , Da Sun, Laura Hertz, Siyuan  He, and Zheng-Rong Lu

103

Identification of splicing regulators using retroviral vectors carrying intron-containing expression cassettes

Mukta Asnani, Elena Sotillo, Asen Bagashev, Ophir Shalem, and Andrei Thomas-Tikhonenko

104

A novel long noncoding RNA regulates the cAMP dependent pathway in human brown adipocytes

Soren Nielsen, Cecilie Bus, Sarah Heywood, Therese Larsen, Naja Jespersen, Bente Pedersen, and Camilla Scheele

105

A diversity of functionally critical arginine methylation in endogenous RNAi

Ryan Bell, Nancie Mooney, Peter Jackson, and Andrew Fire

106

Epigenetic prerequisites for the production of distinct types of small RNAs in the Drosophila germline

Natalia Akulenko, Sergei Ryazansky, Chantal Vaury, Alla Kalmykova, and Silke Jensen

107

Functional in vivo screening to identify microRNAs driving metastatic dissemination of prostate cancer cells to different sites

Tina Catela Ivkovic, Helena Cornella, Margareta Persson, Robert Rigo, Sofia Gruvberger-Saal, Lao Saal, and Yvonne Ceder

108

Genome-wide analysis of lncRNA expression patterns in Drosophila

Henry Krause, Ronit Wilk, and Jack Hu

109

Mechanisms involved in DICER1 downregulation and cell transformation in thyroid cancer

Julia Ramírez-Moya, León Wert-Lamas, and Pilar Santisteban

110

Functional dissection of lincRNAs by systematic mapping of their genetic interactions

Antonis Kirmizis, Dimitris Kyriakou, Emmanouil Stavrou, Panayiota Demosthenous, Georgia Angelidou, Bryan-Joseph San Luis, Charlie Boone, and Vasilis Promponas

111

Mammalian PNLDC1 deadenylase is specifically expressed during early development and affects the expression of long non-coding and piRNAs

Ilias Skeparnias, Dimitrios Anastasakis, Athanasios-Nasir Shaukat, Katerina Grafanaki, Athanasios Papakyriakou, and Constantinos Stathopoulos

112

Adenoviral miRNAs and the change of the cellular/viral targetome during infection

Florian Bellutti, Maximilian Kauer, and Reinhard Klein

113

Specific inhibition of eIF4A-dependent viral mRNA translation by Silvestrol as a potent antiviral approach

Arnold Grünweller, Christin Müller, Falk Schulte, Kerstin Lange-Grünweller, Martin Schlitzer, Nadine Biedenkopf, Stephan Becker, John Ziebuhr, and Roland Hartmann

114

Function of PIWI proteins and piRNAs in bovine oocytes

Minjie Tan, Helena van Tol, Tom Stout, and Bernard Roelen

115

Investigate the unique role of non-coding RNAs during Endothelial Cells differentiation through cell reprogramming as novel treatments for diabetic complications and cardiovascular disease

Magdalini Eleftheriadou

116

Identification of non-canonical miRNA targets functioning in mature miRNA degradation

Yuluan Wang, Charlotte Soneson, Anna  Malinowska, Ugo Pradère, Jochen Imig, Mark Robinson, and Jonathan Hall

117

Circular RNAs in Cancer

Marjan Askarian-Amiri, Debina Sarkar, Herah Hansji, Euphemia Leung, Stefan Bohlander, Kaveesha Bodiyabadu, Graeme Finlay, and Bruce Baguley

118

Oligonucleotide-addressed covalent 3’-terminal derivatization of small RNA strands for enrichment and visualization

Aleksandr Osipenko, Alexandra Plotnikova, Viktoras  Masevicius, Saulius Klimasauskas, and Giedrius Vilkaitis

119

TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs 

Dmytro Ustianenko, Josef Pasulka, Zuzana Feketova, Lukas Bednarik, Dagmar Zigackova, Andrea Fortova, Mihaela  Zavolan, and Stepanka Vanacova

120

Role of miR-182 in neoplastic progression of colorectal cancer

Lisa Perilli, Angela Grassi, Sofia Tessarollo, Donato Nitti, Marco Agostini, Edoardo D'Angelo, Stefania Bortoluzzi, Efrem Brunetti, Massimo Rugge, Laura Albertoni, Matteo Fassan, and Paola Zanovello

121

Polymorphism in miRNAs involved in the risk of pediatric acute lymphoblastic leukemia

Angela Gutierrez-Camino, Idoia Martin-Guerrero, Aurora Navajas, Itziar Astigarraga, and Africa García-Orad

122

New markers of vincristine-induced peripheral neurotoxicity in children with acute lymphoblastic leukemia: SNPs in microRNAs

Umerez Maitane, Angela Gutierrez-Camino, Idoia Martin-Guerrero, Nagore Garcia de Andoin, Ana Sastre, Itziar Astigarraga, and Africa Garcia-Orad

123

14q32 miRNA cluster involved in the risk of Osteosarcoma

Idoia Martin-Guerrero, Angela Gutierrez-Camino, Javier Uriz, and Africa Garcia-Orad

124

Silencing of the long noncoding RNA SPTY2D1-AS1 contributes to thyroid tumorigenesis by derepressing oncomiRs activity

León Wert-Lamas, Alice Fletcher, Laura Ruiz-Cañas, Adrian Acuña, Garcilaso Riesco-Eizaguirre, and Pilar  Santisteban

125

Enhancing miRNA therapeutic efficacy through combinatorial targeting

Esteban Orellana, Alexa Lisevick, and Andrea Kasinski

126

The ARK5:PP1β:PNUTS complex controls nucleolar IGS lncRNAs in MYC-driven tumors

Giacomo Cossa, Isabelle Röschert, Sebastian Letschert, Amit Kumar, Markus Sauer, Stefan Kempa, and Martin Eilers

127

Non-coding RNA as modulator of S.pneumoniae virulence

Alina Martynova

128

The impact of microRNA mediated genes in pre-eclampsia, a human-specific pregnancy disorder

Katarina Stevanovic, Zsuzsanna  Izsvak, and Ralf Dechend

129

A High-Throughput Approach to Profile RNA Structure

Riccardo Delli Ponti, Alexandros Armaos, Stefanie Marti, and Gian Gaetano Tartaglia