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Thursday, 27 June 2024 |
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18:00 PM |
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Conference Registration |
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20:00 PM |
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Welcome Reception - Dinner |
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Friday, 28 June 2024 |
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8:00 AM |
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Breakfast |
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9:00 AM |
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Welcome - Opening Remarks George Kollias |
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SESSION I |
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Chronic Inflammatory Disease |
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9:10 AM |
1 |
Inflammation, damage or pain: Fibroblasts decide Christopher Buckley |
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9:30 AM |
2 |
Regulators of fibroblast-mediated inflammation Michael Brenner |
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9:50 AM |
3 |
Fibroblast lineage structure in health and disease Matthew Buechler |
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10:10 AM |
4 |
Immunotherapeutical targeting of cardiac fibroblasts Burkhard Ludewig |
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10:30 AM |
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Coffee Break and Poster Viewing |
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11:30 AM |
5 |
TBA Allon Wagner |
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11:50 AM |
6 |
Single-cell characterisation of synovial fibroblasts in systemic sclerosis Celina Geiss |
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12:00 PM |
7 |
Regulation of synovial fibroblast activation and expansion in arthritis Fani Roumelioti |
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SESSION II |
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Fibrosis |
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12:10 PM |
8 |
Organ dependency on its surrounding (fascia) connective tissues Yuval Rinkevich |
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12:30 PM |
9 |
Immunotherapeutical targeting of mesenchymal cells in fibrotic disease Christian Stockmann |
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12:50 PM |
10 |
TBA Fiona Oakley |
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13:10 PM |
11 |
A possible profibrotic role of tissue iron in Systemic Sclerosis Nikolaos Vlachogiannis |
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13:20 PM |
12 |
Selective inhibition of myofibroblast phenotype by blood pressure drug telmisartan CheMin Lee |
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13:30 PM |
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Lunch |
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15:00 PM |
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Informal Discussions |
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19:30 PM |
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Dinner and Informal Discussions (Buses Depart from Hotel Lobby) |
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Saturday, 29 June 2024 |
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8:00 AM |
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Breakfast |
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SESSION III |
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ECM and mechanotransduction |
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8:30 AM |
13 |
THE EMBO LECTURE: Cell and tissue mechanoadaption: molecular mechanisms and physiopathological relevance Miguel Angel del Pozo |
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8:50 AM |
14 |
Role of the YAP/TAZ mechanotransducers in aging and cancer. A tissue-level perspective Stefano Piccolo |
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9:10 AM |
15 |
Mechanisms maintaining lymph node structure and function Sophie Acton |
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9:30 AM |
16 |
Mechanosensitive and metabolic pathways regulate plasma membrane ATP synthase trafficking in mouse embryonic fibroblasts Aleksandra Norczyk Simón |
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9:40 AM |
17 |
Metabolic reprogramming of Lymph node FRCs govern their proliferation, and function Lalit Dubey |
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SESSION IV |
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Contextually-specified stromal niches |
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9:50 AM |
18 |
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling Roni Nowarski |
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10:10 AM |
19 |
Fibroblast driven causalities in chronic inflammation George Kollias |
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10:30 AM |
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Coffee break and poster viewing |
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11:50 AM |
20 |
Genetic and epigenetic activation of synovial fibroblasts in rheumatoid arthritis Caroline Ospelt |
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12:10 PM |
21 |
Mesenchymal engagements in Psoriatic Arthritis Maria Armaka |
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12:30 PM |
22 |
Fibroblast diversity within human Gut-Associated Lymphoid Tissues in health and inflammatory bowel disease William W. Agace |
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12:50 PM |
23 |
Lymphatic dysfunction of the skin and immune dysregulation Theresa Lu |
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13:10 PM |
24 |
IL-33-mediated fibroblast-myeloid cell crosstalk controls intestinal granuloma formation Angelina De Martin |
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13:20 PM |
25 |
SEPTIN 8 regulates mitochondrial function in fibroblasts Huan Liu |
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13:30 PM |
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Lunch |
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15:00 PM |
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Informal Discussions |
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19:30 PM |
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Dinner and Informal Discussions (Buses Depart from Hotel Lobby) |
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Sunday, 30 June 2024 |
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8:00 AM |
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Breakfast |
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SESSION V |
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Lymphoid organs and Immunity |
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8:30 AM |
26 |
Neuroimmune interactions in lymphoid tissues Scott Mueller |
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8:50 AM |
27 |
Unravelling stromal cell regulation of the humoral response in lymphoid tissue and beyond Alice Denton |
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9:10 AM |
28 |
Multi-tier coordination of antiviral immunity by fibroblasts Natalia Pikor |
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9:30 AM |
29 |
Characterization of fibroblast subsets within secondary lymphoid organs Sanjiv Luther |
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9:50 AM |
30 |
Linking lymphatics to mesenchymal cells in the developing lymph node Christopher Mueller |
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10:10 AM |
31 |
Spatially resolving fibroblast-tumour interactions in melanoma metastatic lymph nodes Harry Horsnell |
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10:20 AM |
32 |
Pericardial fat-associated lymphoid clusters control T cell activation and differentiation during autoimmune myocarditis Nadine Cadosch |
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10:30 AM |
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Coffee break and poster viewing |
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SESSION VI |
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Stem Cell function and Tissue Regeneration |
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11:30 AM |
33 |
Mesenchymal regulation of intestinal epithelial self-renewal Ramesh A Shivdasani |
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11:50 AM |
34 |
Parallels between wound healing and cancer: A fibroblast perspective Sabin Werner |
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12:10 PM |
35 |
Dietary control of intestinal stem cells in physiology and disease Omer Yilmaz |
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12:30 PM |
36 |
Age-related stromal change drive tumor progression Sheila Stewart |
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12:50 PM |
37 |
Multiple facets of androgen receptor signaling in fibroblast senescence and pro-tumorigenic functions Gian Paolo Dotto |
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13:10 PM |
38 |
Fibroblast diversification is an embryonic process dependent on muscle contraction Lavi Coren |
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13:20 PM |
39 |
Heparan sulfate regulates amphiregulin signaling towards reparative lung mesenchymal cells during influenza A infection Nicholas Arpaia |
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13:30 PM |
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Lunch |
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15:00 PM |
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Guided Tour of Old Town Chania (Buses Depart from Hotel Lobby) |
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19:30 PM |
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Dinner and Informal Discussions (Buses do not return to the hotel prior to dinner) |
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Monday, 01 July 2024 |
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8:00 AM |
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Breakfast |
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SESSION VII |
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From Fibroblast States to Tumor Programs |
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8:30 AM |
40 |
Evolution of mesenchymal cell in carcinomas Ruth Scherz-Shouval |
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8:50 AM |
41 |
Stromal and immune plasticity shape the metastatic microenvironment Neta Erez |
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9:10 AM |
42 |
Development and underlying mechanisms of fibroblastic states within the antigen-presenting cell landscape in cancer Maria Tsoumakidou |
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9:30 AM |
43 |
Mechanisms and consequences of pancreatic cancer stromal evolution Mara Sherman |
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9:40 AM |
44 |
Cancer-associated fibroblasts influence Treg cell dynamics in lung cancer Olivia Ringham |
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9:50 AM |
45 |
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma Alan Ramsay |
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SESSION VIII |
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Molecular Basis of Fibroblast-Dependent Tumor Processes |
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10:00 AM |
46 |
Functional Role of Tissue Damage & Regenerative Response in Cancer Progression & Metastasis Raghu Kalluri |
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10:20 AM |
47 |
Identifying conserved, targetable pathways of immune suppression in the tumour microenvironment Anne Fletcher |
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10:40 AM |
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Coffee break and poster viewing |
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SESSION VIII |
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Molecular Basis of Fibroblast-Dependent Tumor Processes |
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11:40 PM |
48 |
Dynamics of tumour immune microenvironments Mark Coles |
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12:00 PM |
49 |
Mesenchymal activation and functions in intestinal carcinogenesis Vassiliki Koliaraki |
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12:20 PM |
50 |
Cell plasticity in pathogenesis and therapy of colorectal cancer Florian Greten |
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12:40 PM |
51 |
High-fat Western diet supports colorectal cancer progression by promoting mucin secretion and infiltration of cancer-associated fibroblasts Stefania Vetrano |
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12:50 PM |
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Round table “The future of mesenchymal research” Laurie Dempsey – George Kollias – Maria Tsoumakidou – Gian-Paolo Dotto - Christopher Buckley – Scott Mueller – Ruth Scherz-Shouval |
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13:30 PM |
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Lunch |
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15:00 PM |
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Informal Discussions |
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20:00 PM |
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Farewell Dinner |
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Tuesday, 02 June 2024 |
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8:00 AM |
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Breakfast |
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Departure |